scholarly journals P756 Paradoxycal restricted motion in diastole associated to mitral valve prolapse/dystrophy: a frequent finding

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
T Le Tourneau ◽  
C Cueff ◽  
M Marrec ◽  
N Piriou ◽  
R Capoulade ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Prolapse ◽  
Mitral Annulus ◽  
Valve Leaflet ◽  
Filamin A ◽  
Mitral Valve Leaflet ◽  
Frequent Finding ◽  
Valve Annulus ◽  
Leaflet Prolapse ◽  
Funding Acknowledgements

Abstract Funding Acknowledgements PHRCI mitral 2012 Background Filamin-A mitral valve prolapse/dystrophy (FLNA-MVP) phenotype associates moderate MVP and a paradoxical restricted motion in diastole. Purpose We aimed to assess the association of MVP with restricted motion in diastole in MVP patients (restricted MVP). Methods We prospectively enrolled 433 MVP probands (57 ± 16 years). Patients underwent a clinical examination and a comprehensive echocardiographic analysis of mitral valve apparatus. Results Among the 433 probands, 27 (6.2%, 95% CI 3.9-8.5) had both a MVP and a doming aspect in diastole. Patients with restricted MVP exhibited shorter posterior chordae tendinaes (24.8 ± 6.3 vs 27.2 ± 5.9 mm, P = 0.037), and a shorter distance between papillary muscle (PM) tips and mitral annulus (anterior PM: P = 0.0001; posterior PM: P = 0.009). Anterior mitral valve leaflet was lengthened (15.5 ± 2.4 vs 14.3 ± 2.6 mm/m², P = 0.018), but leaflet thickness, leaflet prolapse, and mitral valve annulus did not differ between the 2 groups. Bicuspid aortic valve was more frequent in patients with restricted phenotype (14.8 vs 2.9%, P < 0.05). Familial recurrence of restricted MVP was identified even in the absence of Filamin-A mutation. Conclusion Restricted MVP is a quite frequent finding in MVP patients and is associated with PM tips location closer to mitral annulus. Restricted MVP can be regarded as a third type of MVP beside myxomatous Barlow disease and fibro-elastic deficiency MVP.

P6490Paradoxycal restricted motion in diastole is a frequent finding in mitral valve prolapse/dystrophy patients

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
T Le Tourneau ◽  
C Cueff ◽  
N Piriou ◽  
R Capoulade ◽  
S Le Scouarnec ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Aortic Valve ◽  
Clinical Examination ◽  
Papillary Muscle ◽  
Mitral Valve Prolapse ◽  
Mitral Annulus ◽  
Filamin A ◽  
Familial Form ◽  
Frequent Finding ◽  
Valve Annulus

Abstract Background Filamin-A mitral valve prolapse/dystrophy (FLNA-MVP) phenotype associates MVP and a paradoxical restricted motion in diastole. Purpose We aim to assess the association of mitral valve prolapse to restricted motion in diastole in MVP patients (restricted MVP). Methods We prospectively enrolled 475 MVP probands (64±13 years) and controls relatives. Patients underwent a clinical examination and a comprehensive echocardiographic analysis of mitral valve apparatus. Results Among 475 consecutive probands, 48 (10.1%, 95% CI 7.7–13.3) had both a MVP and a doming aspect in diastole. Patients with restricted MVP exhibited shorted chordae tendinaes, and a shorter distance between papillary muscle tip and mitral annulus. Compared with controls, mitral valve leaflets were lenghtened, thickened and mitral valve annulus was enlarged. The prevalence of polyvalvular disease and bicuspid aortic valve was not increased in restricted MVP patients compared with conventional MVP. Familial form of restricted MVP was identified even in the absence of Filamin-A mutation. Conclusion Restricted MVP is a quite frequent finding in MVP patients and is associated with unique features of the MV apparatus. Restricted MVP can be regarded as a third type of MVP beside myxomatous Barlow disease and fibro-elastic deficiency MVP. Acknowledgement/Funding PHRC I Mitral, Fédération Française de Cardiologie, Fondation Coeur et recherche

scholarly journals Mitral valve repair in Barlow’s disease with bileaflet prolapse: the effect of annular stabilization on functional mitral valve leaflet prolapse†

2017 ◽  
Vol 26 (4) ◽  
pp. 559-565 ◽  
Author(s):  
Anton Tomšič ◽  
Yasmine L Hiemstra ◽  
Daniella D Bissessar ◽  
Thomas J van Brakel ◽  
Michel I M Versteegh ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Valve Leaflet ◽  
Valve Repair ◽  
Mitral Valve Leaflet ◽  
Barlow’S Disease ◽  
Leaflet Prolapse

Anterior Mitral Valve Leaflet Prolapse

2018 ◽  
pp. 139-151
Author(s):  
Narain Moorjani ◽  
Bushra S. Rana ◽  
Francis C. Wells
Keyword(s):  
Mitral Valve ◽  
Valve Leaflet ◽  
Mitral Valve Leaflet ◽  
Leaflet Prolapse

scholarly journals Criteria for adverse prognosis for mitral valve prolapse.

2019 ◽  
Vol 21 (4) ◽  
pp. 64-66
Author(s):  
Yu V Ovchinnikov ◽  
L R Gadzhieva ◽  
M V Palchenkova ◽  
N V Muracheva ◽  
S B Tkachenko
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Prolapse ◽  
Left Atrial ◽  
Poor Prognosis ◽  
Left Ventricular ◽  
Left Ventricular Cavity ◽  
Severe Mitral Regurgitation ◽  
Valve Leaflet ◽  
Ecg Monitoring ◽  
Mitral Valve Leaflet

On the basis of a survey of 151 patients, diagnostic criteria for an unfavorable prognosis of mitral valve prolapse were revealed according to echocardiography. Transthoracic and transesophageal echocardiography, daily Holter ECG monitoring were performed. Repeated echocardiography was performed in 12-18 months. Statistical analysis of the material allowed us to identify criteria for poor prognosis of mitral valve prolapse according to echocardiography: severe mitral regurgitation, mitral valve leaflet thickness in diastole 6 mm or more, dilatation of the left ventricular cavity, dilatation of the left atrial cavity, dilatation of the mitral ring.

scholarly journals Mitral degenerative valve leaflets suspected as primary valvular tumor: a case report

2021 ◽  
Author(s):  
Shiqiang Wang ◽  
Huaidong Chen ◽  
Ximing Qian ◽  
Fan He
Keyword(s):  
Heart Disease ◽  
Case Report ◽  
Mitral Valve ◽  
Rare Case ◽  
Clinical Symptoms ◽  
Clinical Decision ◽  
Valve Leaflet ◽  
Mitral Valve Leaflet ◽  
Valvular Tumor ◽  
Leaflet Prolapse

Introduction: Echocardiography plays an important role in the diagnosis of heart disease. However, sometimes misdiagnosis information is also provided. Methods and Results: We report a rare case of preoperative echocardiography misdiagnosed as a primary mitral valvular tumor with severe regurgitation. During the surgery procedure, the true lesion was found to be mitral valve leaflet prolapse due to degenerative mitral valve disease. Conclusions: For individual patient, it may need to combine clinical symptoms and wide use of echocardiography and CT or MRI to make the optimal clinical decision.

Posterior Mitral Valve Leaflet Prolapse

2018 ◽  
pp. 123-137
Author(s):  
Narain Moorjani ◽  
Bushra S. Rana ◽  
Francis C. Wells
Keyword(s):  
Mitral Valve ◽  
Valve Leaflet ◽  
Mitral Valve Leaflet ◽  
Leaflet Prolapse
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