scholarly journals P3473Outcome following assessment for orthotopic heart transplant in adults with congenital heart disease

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
D Crossland ◽  
K Jansen ◽  
J J O'Sullivan ◽  
K E Best ◽  
G Parry ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplant ◽  
Congenital Heart ◽  
Orthotopic Heart Transplant

scholarly journals Outcome following heart transplant assessment in adults with congenital heart disease

Heart ◽  
2019 ◽  
Vol 105 (22) ◽  
pp. 1741-1747 ◽  
Author(s):  
David Steven Crossland ◽  
Katrijn Jansen ◽  
Gareth Parry ◽  
Andrew Harper ◽  
Gianluigi Perri ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplant ◽  
Congenital Heart ◽  
Conventional Surgery ◽  
Orthotopic Heart Transplant ◽  
Ventricular Assist ◽  
Systemic Right Ventricle ◽  
End Stage Heart Failure ◽  
End Stage

ObjectivesAdults with congenital heart disease (ACHD) are a growing group with end-stage heart failure. We aim to describe the outcomes of ACHD patients undergoing assessment for orthotopic heart transplant (OHT).MethodsCase notes of consecutive ACHD patients (>16 years) assessed for OHT between 2000 and 2016 at our centre were reviewed. Decision and outcome were reported as of 2017. Data were analysed in three groups: systemic left ventricle (LV), systemic right ventricle (RV) and single ventricle (SV).Results196 patients were assessed (31.8 years, 27% LV, 29% RV, 44% SV). 89 (45%) patients were listed for OHT and 67 (34%) were transplanted. 41 (21%) were unsuitable or too high risk and 36 (18%) were too well for listing. Conventional surgery was undertaken in 13 (7%) and ventricular assist device in 17 (9%) with 7 (4%) bridged to candidacy. Survival from assessment was 84.2% at 1 year and 69.7% at 5 years, with no difference between groups. Patients who were considered unsuitable for OHT (HR 11.199, p<0.001) and listed (HR 3.792, p=0.030) were more likely to die than those who were considered too well. Assessments increased over the study period.ConclusionsThe number of ACHD patients assessed for OHT is increasing. A third are transplanted with a small number receiving conventional surgery. Those who are unsuitable have a poor prognosis.

Heart Transplant in Grown Up Congenital Heart Disease.

2014 ◽  
Vol 98 ◽  
pp. 429
Author(s):  
D. Absi ◽  
Peradejordi M. Lastras ◽  
L. Favaloro ◽  
Lopez M. Rosetti ◽  
R. Favaloro ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplant ◽  
Congenital Heart

Outcome of Adults with Congenital Heart Disease Evaluated for Heart Transplant: A Multi-Center Study

2013 ◽  
Vol 32 (4) ◽  
pp. S165-S166
Author(s):  
D. Boucek ◽  
A.T. Yetman ◽  
E. Yeung ◽  
S. Miyamoto ◽  
A.G. Kfoury ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplant ◽  
Congenital Heart ◽  
Multi Center Study ◽  
Center Study

Abstract 18971: Heart Transplantation for Adult Patients With Congenital Heart Disease: Are the Outcomes Still Worse Than in the General Population in 2015?

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Diego Moguillansky ◽  
Biagio A Pietra ◽  
Frederick J Fricker ◽  
Mark S Bleiweis
Keyword(s):  
Congenital Heart Disease ◽  
Survival Analysis ◽  
Heart Disease ◽  
General Population ◽  
Heart Transplantation ◽  
Heart Transplant ◽  
Congenital Heart ◽  
Medium Term ◽  
General Group

Introduction: Short and medium term outcome after heart transplantation has steadily improved over the last few decades. Outcomes for adult patients with congenital heart disease (ACHD) who undergo transplantation are generally considered to be less favorable. Hypothesis: We hypothesized that the development of heart teams that specialize in ACHD would lead to improved outcomes after transplantation in this population. Methods: We reviewed the records of all patients undergoing first heart transplant at a university center with a dedicated ACHD team over the last 10 years. Patients undergoing re-transplantation were excluded. We looked at short (30 days) and medium term (1 year) survival after heart transplantation in ACHD patients. Results: Between 1/1/05 and 6/10/15, 258 patients underwent heart transplantation. Of the 258 patients, 17 were re-transplants and were excluded. Of the remaining 241 patients, 12 were ACHD patients and 229 were transplanted for other diagnosis (general group). In the general group 184 of 212 (86.8%) patients were alive at 1 year (the remaining 17 did not have sufficient follow up to be included in the 1-year survival analysis). In the ACHD group 9 of 9 patients (100%) were alive at 1 year. The remaining 3 ACHD patients with insufficient follow up to be included in the 1-year survival analysis were still alive 2.5-9.5 months after transplant, such that all 12 ACHD patients survived at least 30 days and were discharged home after heart transplant. At the end of the study period 160 of 229 (70%) patients were still alive in the general group, compared to 8 of 12 (66.7%) in the ACHD group. Conclusions: Short and medium term survival after heart transplantation appears to be no worse for selected ACHD patients compared to the general population. Larger studies with longer follow up are needed to confirm our findings and clarify the intermediate and long-term outcomes of ACHD patients undergoing heart transplantation in the modern era.

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