Surgery for supraventricular tachycardia and congenital heart defects: long-term efficacy of the combined approach in adult patients

A felnőttkorban operált veleszületett szívhibák között vezetnek az I. rekonstrukciós beavatkozások: a) frissen felismert betegségek, b) megelőzően inoperábilisnak ítélt kórképek, c) pulmonalis hypertonia, jobbkamra-elégtelenség miatt „elkésett” műtétek. Növekszik a II. REDO műtétek száma: a) residuumok korrigálása, b) kinőtt, diszfunkciós homograftok cseréje, c) műtéti/intervenciós korrigálás utáni recoarctatio (aneurysma, dissectio) sebészete, d) aorta valvulotomia/valvuloplastica, illetve társvitiumok (TGA) korrigálásának következményeként Ross-műtét, műbillentyű-beültetés . Betegek, eredmények: A 2001–2008 között végzett 4496 műtét közül 166 volt fiatal-felnőtt korú (16–52, átlagéletkor: 28 év) (Ia: 77, Ib: 15, Ic: 4, IIa: 11, IIb: 22, IIc: 9, IId: 28). Műtéti mortalitás nem volt, 1 beteg pulmonalis hypertoniás krízisben, 1 jobbkamra-elégtelenség miatti malignus ritmuszavarban, 2 többszerv-elégtelenségben halt meg. Konklúzió: A rizikófaktorokat a pulmonalis hypertonia és a jobbkamra-elégtelenség jelenti. A bonyolult sebészi megoldások a „congenitalis szívsebész” számára nem jelentenek problémát, de koraibb diagnózisok, terápiában az extracorporalis membránoxigenátor használata az eredményeket javíthatja.

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Electrophysiology assessment and radiofrequency ablation of arrhythmias in adult patients with congenital heart defects: The Christchurch experience

Heart Lung and Circulation ◽

10.1016/j.hlc.2014.04.183 ◽

2014 ◽

Vol 23 ◽

pp. e22

Author(s):

M. Daly ◽

K. Frankish ◽

J. Greenslade ◽

S. Denekamp ◽

J. Lainchbury ◽

...

Keyword(s):

Radiofrequency Ablation ◽

Congenital Heart Defects ◽

Congenital Heart ◽

Heart Defects ◽

Adult Patients

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Long-term Neurodevelopmental Outcomes of Children with Congenital Heart Defects

The Journal of Pediatrics ◽

10.1016/j.jpeds.2021.06.032 ◽

2021 ◽

Author(s):

Neil Derridj ◽

Romain Guedj ◽

Johanna Calderon ◽

Lucile Houyel ◽

Nathalie Lelong ◽

...

Keyword(s):

Congenital Heart Defects ◽

Congenital Heart ◽

Heart Defects ◽

Neurodevelopmental Outcomes

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Immediate and long-term outcomes in children with prenatal diagnosis of selected isolated congenital heart defects

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.3900 ◽

2007 ◽

Vol 29 (1) ◽

pp. 38-43 ◽

Cited By ~ 55

Author(s):

I. B. Fuchs ◽

H. Müller ◽

H. Abdul-Khaliq ◽

T. Harder ◽

J. W. Dudenhausen ◽

...

Keyword(s):

Prenatal Diagnosis ◽

Congenital Heart Defects ◽

Congenital Heart ◽

Heart Defects ◽

Long Term Outcomes

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Abstract 18284: Incidence of Epilepsy is Elevated in Children and Young Adults With Congenital Heart Defects Compared With the General Population: A Nationwide Cohort Study

Circulation ◽

10.1161/circ.132.suppl_3.18284 ◽

2015 ◽

Vol 132 (suppl_3) ◽

Author(s):

Morten Olsen ◽

Bradley S Marino ◽

Michelle Leisner ◽

Jessica G Woo ◽

Nicolas L Madsen

Keyword(s):

Young Adults ◽

Preterm Birth ◽

General Population ◽

Congenital Heart Defects ◽

Congenital Heart ◽

Heart Defects ◽

Birth Registry ◽

Registration System ◽

Children And Young Adults

Perioperative seizures related to surgery for congenital heart defects (CHD) are well described; however, few data exist on the long-term risk of epilepsy in patients with CHD. We aimed to estimate the incidence of epilepsy in children and young adults with CHD compared with the general population. Methods: Utilizing data from the Danish National Registry of Patients (DNRP) we identified all patients diagnosed with CHD before the age of 15 years between 1980 and 2010 who were born during the same period. The DNRP is a nationwide hospital discharge registry covering all Danish hospitals. Previously validated methodology using the DNRP was applied to measure the outcome, epilepsy, as well as presence of extra cardiac defects (ECD) and/or syndromes. We used the Danish Medical Birth Registry to identify preterm birth (gestational age<37 weeks). For each CHD subject, we identified 10 controls from the general population using the Danish Civil Registration System, matched by sex and birth year. A unique personal identifier assigned at birth and used in all Danish public registries enabled virtually complete follow up for migration, death, or epilepsy until January 1, 2013. We computed cumulative incidences and hazard ratios (HR) (split at 5 years of age to obtain proportional hazards) of time from CHD diagnosis (index date for controls) to epilepsy. Results: We identified 14,665 CHD subjects with a median age at diagnosis of 2 (IQR 19) months. By 15 years of age, the cumulative incidence of epilepsy was 4% among CHD subjects. The HR of epilepsy among CHD subjects compared with the control cohort was 3.7 (95% CI: 3.2-4.3) below 5 years of age, and 2.4 (95% CI: 2.1-2.7) from 5 to 33 years of age. In the older age group, HR for patients with severe CHD was 2.8 (95% CI: 2.3-3.5), and for mild and moderate CHD was 2.2 (95% CI: 1.8-2.6). After exclusion of all subjects with ECDs and/or syndromes and preterm birth, corresponding HRs were 2.2 (95% CI: 1.6-3.0) and 1.7 (95% CI: 1.3-2.2), respectively. Conclusion: The epilepsy risk was markedly increased in CHD subjects compared with the age and gender matched controls. These findings add evidence to support the importance of developing neuro-protective measures and potentially long-term epilepsy surveillance strategies in the CHD population.

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