scholarly journals Recruitment of galectin-3 during cell invasion and intracellular trafficking of Trypanosoma cruzi extracellular amastigotes

Glycobiology ◽  
2013 ◽  
Vol 24 (2) ◽  
pp. 179-184 ◽  
Author(s):  
F. C. Machado ◽  
L. Cruz ◽  
A. A. da Silva ◽  
M. C. Cruz ◽  
R. A. Mortara ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Cell Invasion ◽  
Intracellular Trafficking ◽  
Galectin 3 ◽  
Extracellular Amastigotes

scholarly journals ERM Proteins Play Distinct Roles in Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi

2017 ◽  
Vol 8 ◽  
Author(s):  
Éden R. Ferreira ◽  
Alexis Bonfim-Melo ◽  
Esteban M. Cordero ◽  
Renato A. Mortara
Keyword(s):  
Trypanosoma Cruzi ◽  
Cell Invasion ◽  
Erm Proteins ◽  
Extracellular Amastigotes

Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion

2017 ◽  
Vol 25 (21) ◽  
pp. 6049-6059 ◽  
Author(s):  
Marcelo Fiori Marchiori ◽  
Thalita B. Riul ◽  
Leandro Oliveira Bortot ◽  
Peterson Andrade ◽  
Getúlio G. Junqueira ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Cell Invasion ◽  
Galectin 3

scholarly journals Trypanosoma cruzi extracellular amastigotes selectively trigger the PI3K/Akt and Erk pathways during HeLa cell invasion

2019 ◽  
Vol 21 (10) ◽  
pp. 485-489 ◽  
Author(s):  
Bianca Lima Ferreira ◽  
Éden Ramalho Ferreira ◽  
Alexis Bonfim-Melo ◽  
Renato Arruda Mortara ◽  
Diana Bahia
Keyword(s):  
Trypanosoma Cruzi ◽  
Hela Cell ◽  
Cell Invasion ◽  
Extracellular Amastigotes

scholarly journals A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes

2018 ◽  
Vol 9 ◽  
Author(s):  
Pilar T. V. Florentino ◽  
Fernando Real ◽  
Cristina M. Orikaza ◽  
Julia P. C. da Cunha ◽  
Francisca N. L. Vitorino ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Host Cell ◽  
Cell Invasion ◽  
Carbohydrate Moiety ◽  
Host Cell Invasion ◽  
Extracellular Amastigotes

scholarly journals Human Galectin-3 Promotes Trypanosoma cruzi Adhesion to Human Coronary Artery Smooth Muscle Cells

2004 ◽  
Vol 72 (11) ◽  
pp. 6717-6721 ◽  
Author(s):  
Yuliya Y. Kleshchenko ◽  
Tapria N. Moody ◽  
Vyacheslav A. Furtak ◽  
Josiah Ochieng ◽  
Maria F. Lima ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Coronary Artery ◽  
Trypanosoma Cruzi ◽  
Smooth Muscle Cells ◽  
Muscle Cells ◽  
Human Cells ◽  
Human Coronary Artery ◽  
Dramatic Decrease ◽  
Galectin 3 ◽  
Initial Capacity

ABSTRACT Human galectin-3 binds to the surface of Trypanosoma cruzi trypomastigotes and human coronary artery smooth muscle (CASM) cells. CASM cells express galectin-3 on their surface and secrete it. Exogenous galectin-3 increased the binding of T. cruzi to CASM cells. Trypanosome binding to CASM cells was enhanced when either T. cruzi or CASM cells were preincubated with galectin-3. Cells stably transfected with galectin-3 antisense show a dramatic decrease in galectin-3 expression and very little T. cruzi adhesion to cells. The addition of galectin-3 to these cells restores their initial capacity to bind to trypanosomes. Thus, host galectin-3 expression is required for T. cruzi adhesion to human cells and exogenous galectin-3 enhances this process, leading to parasite entry.

scholarly journals Trypanosoma cruzi trypomastigotes induce cytoskeleton modifications during HeLa cell invasion

2011 ◽  
Vol 106 (8) ◽  
pp. 1014-1016 ◽  
Author(s):  
Maria Cecília Fernandes ◽  
Leonardo Rodrigues de Andrade ◽  
Norma Windsor Andrews ◽  
Renato Arruda Mortara
Keyword(s):  
Trypanosoma Cruzi ◽  
Hela Cell ◽  
Cell Invasion
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