scholarly journals Early graft failure after heart transplant: risk factors and implications for improved donor-recipient matching

2012 ◽  
Vol 15 (1) ◽  
pp. 57-62 ◽  
Author(s):  
C. Amarelli ◽  
L. S. De Santo ◽  
C. Marra ◽  
C. Maiello ◽  
C. Bancone ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Transplant ◽  
Graft Failure ◽  
Early Graft ◽  
Early Graft Failure

scholarly journals PVSS15. Risk Factors for Surgical Site Infections and Early Graft Failure Following Dialysis Access Procedures

2011 ◽  
Vol 53 (6) ◽  
pp. 10S-11S
Author(s):  
Dorian J. deFreitas ◽  
David Benkeser ◽  
Ravi Veeraswamy ◽  
Thomas Dodson ◽  
Joseph Ricotta ◽  
...  
Keyword(s):  
Risk Factors ◽  
Graft Failure ◽  
Surgical Site Infections ◽  
Dialysis Access ◽  
Early Graft ◽  
Early Graft Failure

scholarly journals Should Heart Transplant Recipients With Early Graft Failure Be Considered for Retransplantation?

2011 ◽  
Vol 92 (3) ◽  
pp. 923-928 ◽  
Author(s):  
Alexander Iribarne ◽  
Kimberly N. Hong ◽  
Rachel Easterwood ◽  
Jonathan Yang ◽  
Valluvam Jeevanandam ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Graft Failure ◽  
Transplant Recipients ◽  
Early Graft ◽  
Heart Transplant Recipients ◽  
Early Graft Failure

scholarly journals Rebubbling and graft failure in Descemet membrane endothelial keratoplasty: a prospective Dutch registry study

2021 ◽  
pp. bjophthalmol-2020-317041
Author(s):  
Suryan Dunker ◽  
Bjorn Winkens ◽  
Frank van den Biggelaar ◽  
Rudy Nuijts ◽  
Pieter Jan Kruit ◽  
...  
Keyword(s):  
Risk Factors ◽  
Endothelial Cell ◽  
Graft Failure ◽  
Surgical Complication ◽  
Multivariable Analysis ◽  
Registry Study ◽  
Recipient Age ◽  
Early Graft ◽  
Independent Risk Factors ◽  
Early Graft Failure

AimsTo identify risk factors for rebubbling, and early graft failure after Descemet membrane endothelial keratoplasty (DMEK).MethodsIn this prospective registry study, all consecutive DMEK procedures registered in the Netherlands Organ Transplant Registry were assessed (n=752). Univariable and multivariable analysis was performed using logistic regression. The effect of rebubbling on endothelial cell density was analysed using a linear mixed model.Results144 of 752 (19%) eyes underwent rebubbling. Rebubbling was successful in 101 eyes (70%). In eyes that underwent rebubbling, the graft failure rate was significantly higher than eyes that did not undergo rebubbling (30% vs 9%, respectively; OR: 4.28, 95% CI 2.72 to 6.73, p<0.001). In multivariable analysis, independent risk factors for rebubbling were surgical complication (OR: 2.28, 95% CI 1.20 to 4.33, p=0.012) and older recipient age (OR: 1.04 (per increase of 1 year), 95% CI 1.01 to 1.07, p=0.003). Risk factors for developing graft failure within 3 months were transplant before 2016 (OR: 3.32, 95% CI 1.87 to 5.90, p<0.001), and surgical complication (OR: 2.93, 95% CI 1.42 to 6.04, p=0.004). Throughout the study period, rebubbling and early graft failure were inversely related. Eyes that underwent rebubbling showed significantly lower endothelial cell densities at 3, 6 and 12 months compared with eyes that did not undergo rebubbling (all p<0.001).ConclusionsThis Dutch registry study identified independent risk factors for DMEK graft detachment leading to rebubbling, namely recipient age and surgical complication, and early graft failure, namely transplantation before 2016 and surgical complication. Rebubbling was associated with significantly higher endothelial cell loss in the first year after surgery.

scholarly journals Risk Factors for Early Graft Failure and Death After Kidney Transplantation in Recipients Older Than 70 Years

2019 ◽  
Vol 4 (5) ◽  
pp. 656-666 ◽  
Author(s):  
Mathilde Lemoine ◽  
Dimitri Titeca Beauport ◽  
Thierry Lobbedez ◽  
Gabriel Choukroun ◽  
Bruno Hurault de Ligny ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Transplantation ◽  
Graft Failure ◽  
Early Graft ◽  
Early Graft Failure

Platelet Adhesion in Polytetrafluoroethylene (PTFE) Vascular Grafts In Vivo and the Influence of Increased Intramuscular Pressure-An Experimental Model

1983 ◽  
Vol 50 (04) ◽  
pp. 881-884 ◽  
Author(s):  
J T Christenson ◽  
P Qvarfordt ◽  
S-E Strand ◽  
D Arvidsson ◽  
T Sjöberg ◽  
...  
Keyword(s):  
Blood Flow ◽  
Graft Failure ◽  
Small Diameter ◽  
Graft Material ◽  
Intramuscular Pressure ◽  
Initial Flow ◽  
Early Graft ◽  
Wick Technique ◽  
Early Graft Failure

SummaryThrombogenicity of graft material is involved in early graft failure in small diameter grafts. The frequently seen postoperative swelling of the leg after distal revascularization may cause an increased intramuscular pressure and early graft failure.Pairs of 4 mm polytetrafluoroethylene (PTFE) grafts were implanted. Autologous platelets were labeled with mIn-oxine. Platelet adhesiveness onto the grafts were analyzed from gamma camera images. Intramuscular pressures were measured with wick technique. Blood flow was measured. One graft served as control the other as test graft. Ninety minutes after declamping the i. m. pressure was increased in the test-leg to 30 mmHg, and later to 60 mmHg.In the control-graft platelet uptake increased to a maximum 60 min after declamping. Blood flow and i.m. pressure remained uneffected. The test-grafts were initially similar but when i.m. pressure was increased to 30 mmHg activity in the grafts increased significantly. Blood flow decreased with 12% of initial flow. When i. m. pressure was raised to 60 mmHg platelet uptake continued to increase.An increased intramuscular pressure of 30 mmHg or more significantly increase the amount of platelets adhering onto PTFE grafts, emphasizing the need for measuring intramuscular pressures after lower limb vascular revascularizations.

Correlation of laboratory and ECG changes with early graft failure after CABG

2005 ◽  
Vol 53 (S 01) ◽  
Author(s):  
A Schnell ◽  
A Künzli ◽  
B Seifert ◽  
O Reuthebuch ◽  
M Lachat ◽  
...  
Keyword(s):  
Graft Failure ◽  
Ecg Changes ◽  
Early Graft ◽  
Early Graft Failure

Virchow Triad, but Not Use of an Aortic Connector Device, Predicts Early Graft Failure after Off-Pump Coronary Bypass

2004 ◽  
Vol 7 (5) ◽  
pp. E428-E433 ◽  
Author(s):  
Robert Poston ◽  
Charles White ◽  
Katrina Read ◽  
Junyan Gu ◽  
Andrew Lee ◽  
...  
Keyword(s):  
Graft Failure ◽  
Coronary Bypass ◽  
Off Pump ◽  
Early Graft ◽  
Early Graft Failure ◽  
Aortic Connector

scholarly journals Prediction model for early graft failure after liver transplantation using aspartate aminotransferase, total bilirubin and coagulation factor

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jinsoo Rhu ◽  
Jong Man Kim ◽  
Kyunga Kim ◽  
Heejin Yoo ◽  
Gyu-Seong Choi ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Prediction Model ◽  
Aspartate Aminotransferase ◽  
Graft Failure ◽  
Living Donor ◽  
Total Bilirubin ◽  
Deceased Donor ◽  
Time Dependent ◽  
Early Graft ◽  
Early Graft Failure

AbstractThis study was designed to build models predicting early graft failure after liver transplantation. Cox regression model for predicting early graft failure after liver transplantation using post-transplantation aspartate aminotransferase, total bilirubin, and international normalized ratio of prothrombin time was constructed based on data from both living donor (n = 1153) and deceased donor (n = 359) liver transplantation performed during 2004 to 2018. The model was compared with Model for Early Allograft Function Scoring (MEAF) and early allograft dysfunction (EAD) with their C-index and time-dependent area-under-curve (AUC). The C-index of the model for living donor (0.73, CI = 0.67–0.79) was significantly higher compared to those of both MEAF (0.69, P = 0.03) and EAD (0.66, P = 0.001) while C-index for deceased donor (0.74, CI = 0.65–0.83) was only significantly higher compared to C-index of EAD. (0.66, P = 0.002) Time-dependent AUC at 2 weeks of living donor (0.96, CI = 0.91–1.00) and deceased donor (0.98, CI = 0.96–1.00) were significantly higher compared to those of EAD. (both 0.83, P < 0.001 for living donor and deceased donor) Time-dependent AUC at 4 weeks of living donor (0.93, CI = 0.86–0.99) was significantly higher compared to those of both MEAF (0.87, P = 0.02) and EAD. (0.84, P = 0.02) Time-dependent AUC at 4 weeks of deceased donor (0.94, CI = 0.89–1.00) was significantly higher compared to both MEAF (0.82, P = 0.02) and EAD. (0.81, P < 0.001). The prediction model for early graft failure after liver transplantation showed high predictability and validity with higher predictability compared to traditional models for both living donor and deceased donor liver transplantation.

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