Detection of Human Herpesvirus 6 in Tissues Involved by Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease)

1992 ◽  
Vol 166 (2) ◽  
pp. 291-295 ◽  
Author(s):  
P. H. Levine ◽  
N. Jahan ◽  
P. Murari ◽  
M. Manak ◽  
E. S. Jaffe
Keyword(s):  
Human Herpesvirus ◽  
Sinus Histiocytosis ◽  
Human Herpesvirus 6 ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Herpesvirus 6

Extranodal Rosai-Dorfman Disease Presenting as a Solitary Mass with Human Herpesvirus 6 Detection in a Pediatric Patient

2012 ◽  
Vol 15 (4) ◽  
pp. 324-328 ◽  
Author(s):  
Naomi Arakaki ◽  
Guillermo Gallo ◽  
Rodolfo Majluf ◽  
Blanca Diez ◽  
Eugenia Arias ◽  
...  
Keyword(s):  
Pediatric Patient ◽  
Human Herpesvirus ◽  
Human Herpesvirus 6 ◽  
Rosai Dorfman Disease ◽  
Herpesvirus 6

Leukocytoclastic Vasculitis Associated with HHV6-A/ciHHV6-A and HHV6-B Coinfection in an Immunocompetent Woman

2019 ◽  
Vol 19 (2) ◽  
pp. 221-225 ◽  
Author(s):  
Agata Calvario ◽  
Caterina Foti ◽  
Maria Scarasciulli ◽  
Paolo Romita ◽  
Eva Eliassen ◽  
...  
Keyword(s):  
Transcriptional Activity ◽  
Skin Infection ◽  
Leukocytoclastic Vasculitis ◽  
Human Herpesvirus ◽  
Small Vessel Vasculitis ◽  
Case Description ◽  
Human Herpesvirus 6 ◽  
Late Antigen ◽  
Herpesvirus 6 ◽  
Systemic Symptoms

Background and Objective: Leukocytoclastic vasculitis (LCV) is a small vessel vasculitis that can be limited to the skin but may also affect other organs. Often, its cause is unknown. LCV has previously been reported to occur with the reactivation of human herpesvirus 6 (HHV-6). Here, we report a second instance of HHV-6 reactivation in a 43-year-old woman with idiopathic cutaneous LCV. </P><P> Case Description: In this case, the patient was immunocompetent, and testing revealed that she had inherited chromosomally integrated human herpesvirus 6 variant A (iciHHV6-A) with a parallel skin infection of HHV-6B. The integrated ciHHV-6A strain was found to be transcriptionally active in the blood, while HHV-6B late antigen was detected in a skin biopsy. The patient’s rash was not accompanied by fever nor systemic symptoms and resolved over four weeks without any therapeutic intervention.Conclusion:In light of the transcriptional activity documented in our case, further examination of a possible role for HHV-6 in the etiology of LCV is warranted.

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