scholarly journals Bone Marrow–Imprinted Gut-Homing of Plasmacytoid Dendritic Cells (pDCs) in Acute Simian Immunodeficiency Virus Infection Results in Massive Accumulation of Hyperfunctional CD4+pDCs in the Mucosae

2014 ◽  
Vol 211 (11) ◽  
pp. 1717-1725 ◽  
Author(s):  
Haiying Li ◽  
Tristan I. Evans ◽  
Jacqueline Gillis ◽  
Michelle Connole ◽  
R. Keith Reeves
2009 ◽  
Vol 84 (4) ◽  
pp. 1838-1846 ◽  
Author(s):  
Laure Campillo-Gimenez ◽  
Mireille Laforge ◽  
Michèle Fay ◽  
Audrey Brussel ◽  
Marie-Christine Cumont ◽  
...  

ABSTRACT Divergent Toll-like receptor 7 (TLR7) and TLR9 signaling has been proposed to distinguish pathogenic from nonpathogenic simian immunodeficiency virus infection in primate models. We demonstrate here that increased expression of type I interferon in pathogenic rhesus macaques compared to nonpathogenic African green monkeys was associated with the recruitment of plasmacytoid dendritic cells in the lymph nodes and the presence of an inflammatory environment early after infection, instead of a difference in the TLR7/9 response.


2011 ◽  
Vol 50 (2-3) ◽  
pp. 228-234 ◽  
Author(s):  
Elizabeth R. Wonderlich ◽  
Muhamuda Kader ◽  
Viskam Wijewardana ◽  
Simon M. Barratt-Boyes

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