scholarly journals In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis

2002 ◽  
Vol 49 (1) ◽  
pp. 103-111 ◽  
Author(s):  
I. S. Adagu
2006 ◽  
Vol 51 (1) ◽  
Author(s):  
Alicia Gómez-Barrio ◽  
David Montero-Pereira ◽  
Juan Nogal-Ruiz ◽  
José Escario ◽  
Susana Muelas-Serrano ◽  
...  

AbstractA study of some antiparasitic properties of several homoallylamines and related tetrahydroquinolines and quinolines, previously described, was carried out using in vitro activity assays against the epimastigote form of Trypanosoma cruzi and against Trichomonas vaginalis. Unspecific cytotoxicity against murine macrophages was also studied. Although the antichagasic and trichomonacidal activities are not comparable to those of the standard drugs, nifurtimox and metronidazole, some of the compounds exhibit an interesting specific antiparasitic activity.


Parasitology ◽  
2014 ◽  
Vol 142 (04) ◽  
pp. 576-584 ◽  
Author(s):  
JOSÉ LUIS RODRÍGUEZ-CHÁVEZ ◽  
YADIRA RUFINO-GONZÁLEZ ◽  
MARTHA PONCE-MACOTELA ◽  
GUILLERMO DELGADO

1965 ◽  
Vol 51 (6) ◽  
pp. 433-439
Author(s):  
Giovanni Ceriotti ◽  
Luigi Spandrio ◽  
Angelo Agradi

Like cysteine and some of its derivatives, tyrosine inhibits liver catalase not only « in vitro » but also « in vivo ». Among the analogues of tyrosine tested, dihydroxyphenylalanine and dihydroxyphenethylamine possess « in vitro » the same activity as tyrosine; the activity of p-hydroxyphenylethanolamine is lower; phenylalanine is inactive. The «in vitro» activity seems to be directly correlated with the auto-oxidability of the various compounds. None of the analogues of tyrosine tested was active «in vivo». The depressing activity of cysteine and of tyrosine on liver catalase apparently has no relationship with the similar action of tumors.


2016 ◽  
Vol 61 (2) ◽  
Author(s):  
Zubeyde Akin Polat ◽  
Ali Cetin ◽  
Poul B. Savage

AbstractTrichomonosis, caused by the protozoan parasite


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