Evaluation of the in vitro activity of ceragenins against Trichomonas vaginalis

2016 ◽  
Vol 61 (2) ◽  
Author(s):  
Zubeyde Akin Polat ◽  
Ali Cetin ◽  
Poul B. Savage
Keyword(s):  
Trichomonas Vaginalis ◽  
Protozoan Parasite ◽  
Vitro Activity ◽  
In Vitro Activity

AbstractTrichomonosis, caused by the protozoan parasite

scholarly journals In vitro activity of Etanidazole against the protozoan parasite Trypanosoma cruzi

2004 ◽  
Vol 99 (2) ◽  
pp. 233-235 ◽  
Author(s):  
Patricia B Petray ◽  
María J Morilla ◽  
Ricardo S Corral ◽  
Eder L Romero
Keyword(s):  
Trypanosoma Cruzi ◽  
Protozoan Parasite ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals In-vitro Activity of Ferula gummosa Essential Oil and Its Different Extracts on Trichomonas vaginalis

2019 ◽  
Vol 27 (2) ◽  
pp. 1-10
Author(s):  
Mehdi Akbari ◽  
◽  
Dara Dastan ◽  
Mohammad Fallah ◽  
Mohammad Matini ◽  
...  
Keyword(s):  
Essential Oil ◽  
Trichomonas Vaginalis ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals In Vitro Activity of Foeniculum vulgare and Its Main Essential Oil Component Trans-Anethole on Trichomonas vaginalis

2019 ◽  
Author(s):  
Faezeh KARAMI ◽  
Dara DASTAN ◽  
Mohammad FALLAH ◽  
Mohammad MATINI
Keyword(s):  
Gas Chromatography ◽  
Essential Oil ◽  
Trichomonas Vaginalis ◽  
Vitro Activity ◽  
Gas Chromatography Mass Spectrometry ◽  
Major Constituent ◽  
In Vitro Activity ◽  
Foeniculum Vulgare

Background: Trichomoniasis is one of the most common nonviral sexually transmitted infections worldwide which drug-resistant cases of the infection are rising. The aim of the study was to assessment the in vitro activity of Foeniculum vulgare and its main essential oil component on Trichomonas vaginalis. Also phytochemical investigation of F. vulgare essential oil was performed. Methods: Five T. vaginalis isolates subjected to susceptibility testing against essential oil and extracts of F. vulgare and anethole using microtiter plate method. The minimum lethal concentration (MLC) of the natural products was assessed in comparison with metronidazole. Gas chromatography-mass spectrometry and gas chromatography-flame ionization detector was applied for chemical investigation of the essential oil. Results: After 48 hours incubation, the most potent antitrichomonal agents were the methanolic and hexanic extract with MLC of 360 µg/ml and followed by the essential oil and anethole (1600 µg/ml). The isolates were sensitive to metronidazole with a mean MLC of 13.7 µg/ml. E-Anethole (88.41 %) was the major constituent of F. vulgare essential oil. Conclusion: The results suggested in vitro antiprotozoal properties of F. vulgare and anethole against T. vaginalis. Therefore further studies are needed to evaluate their in vivo effects and toxicity.

scholarly journals Antiparasitic properties of homoallylamines and related compounds

2006 ◽  
Vol 51 (1) ◽  
Author(s):  
Alicia Gómez-Barrio ◽  
David Montero-Pereira ◽  
Juan Nogal-Ruiz ◽  
José Escario ◽  
Susana Muelas-Serrano ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Trichomonas Vaginalis ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Antiparasitic Activity ◽  
Murine Macrophages ◽  
Related Compounds

AbstractA study of some antiparasitic properties of several homoallylamines and related tetrahydroquinolines and quinolines, previously described, was carried out using in vitro activity assays against the epimastigote form of Trypanosoma cruzi and against Trichomonas vaginalis. Unspecific cytotoxicity against murine macrophages was also studied. Although the antichagasic and trichomonacidal activities are not comparable to those of the standard drugs, nifurtimox and metronidazole, some of the compounds exhibit an interesting specific antiparasitic activity.

In Vitro Activity of Methanol Extract of Microalgae Hapalosiphon aureus Against Trichomonas vaginalis

2020 ◽  
pp. 34-36
Keyword(s):  
Mass Spectrum ◽  
Secondary Metabolites ◽  
Natural Product ◽  
Trichomonas Vaginalis ◽  
Methanol Extract ◽  
Protozoan Parasite ◽  
In Vitro Activity ◽  
Total Composition ◽  
First Time

The present study targets the protozoan parasite Trichomonas vaginalis that causes a healthy problem among women and rarely among men, by the application of natural product or secondary metabolites extracted from the microalgae Hapalosiphon aureus for the first time in Iraq. methanol extract was explained high activity in three concentration recording 100% of parasite death at 200 µg\ml of methanol extract in about two days while 150 and 100 µg\ml of extract reports activity against the parasite after fourand fivedays post treatment respectively. GC- Mass spectrum of the methanol extract has explain presence of the compound (2- deca - 3,d- dienyloxy) carbonyl benzeoic acid in about 13.28 % from the total composition of methanol extract of microalgae.

scholarly journals In vitro activity of N-chlorotaurine (NCT) in combination with NH4Cl against Trichomonas vaginalis

2011 ◽  
Vol 37 (2) ◽  
pp. 171-173 ◽  
Author(s):  
Ursula Fürnkranz ◽  
Markus Nagl ◽  
Waldemar Gottardi ◽  
Michael Duchêne ◽  
Horst Aspöck ◽  
...  
Keyword(s):  
Trichomonas Vaginalis ◽  
Vitro Activity ◽  
In Vitro Activity
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