scholarly journals Recent Advances in Cancer Vaccines: An Overview

2008 ◽  
Vol 39 (2) ◽  
pp. 73-80 ◽  
Author(s):  
K. Itoh ◽  
A. Yamada ◽  
T. Mine ◽  
M. Noguchi
2014 ◽  
Vol 14 (12) ◽  
pp. 1769-1781 ◽  
Author(s):  
Ira Surolia ◽  
James Gulley ◽  
Ravi A Madan

2017 ◽  
Vol 10 (10) ◽  
pp. 805-814 ◽  
Author(s):  
Hwi Young Kim ◽  
Joong-Won Park

Hepatocellular carcinoma (HCC) is a common and serious health problem with high mortality. Treatment for HCC remains largely unsatisfactory owing to its high recurrence rates and frequent accompanying cirrhosis. In addition, the unique immune environment of the liver promotes tolerance, which, in conjunction with immune evasion by the disease, makes HCC a less promising target for conventional immunotherapy. However, recent advances in the immunotherapy have led to novel approaches to overcome these obstacles by manipulating and enhancing tumor-specific immune responses against HCC by using various modalities, such as cancer vaccines and immune checkpoint blockade. These treatments have shown both safety and promising outcomes in patients with HCC of various etiologies and tumor stages. Furthermore, combined strategies have been assessed to achieve optimal outcomes, by using immunotherapies with or without conventional treatments. This review briefly covers the background, recent advances, current issues, and future perspectives on immunotherapy in the field of HCC treatment.


2020 ◽  
Vol 15 (5) ◽  
pp. 576-590 ◽  
Author(s):  
Jingjing Liu ◽  
Lei Miao ◽  
Jiying Sui ◽  
Yanyun Hao ◽  
Guihua Huang

2003 ◽  
Vol 16 (2) ◽  
pp. 111-121 ◽  
Author(s):  
Gretchen L. Eiben ◽  
Diane M. Da Silva ◽  
Steven C. Fausch ◽  
I. Caroline Le Poole ◽  
Michael I. Nishimura ◽  
...  

2014 ◽  
pp. 159 ◽  
Author(s):  
Giorgio Valabrega ◽  
Andrea Milani ◽  
Massimo Aglietta ◽  
Dario Sangiolo

2019 ◽  
Vol 41 (6-7) ◽  
pp. 641-650 ◽  
Author(s):  
Ke-Tao Jin ◽  
Huan-Rong Lan ◽  
Xiao-Yi Chen ◽  
Shi-Bing Wang ◽  
Xiao-Jiang Ying ◽  
...  

1988 ◽  
Vol 132 ◽  
pp. 525-530
Author(s):  
Raffaele G. Gratton

The use CCD detectors has allowed a major progress in abundance derivations for globular cluster stars in the last years. Abundances deduced from high dispersion spectra now correlates well with other abundance indicators. I discuss some problems concerning the derivation of accurate metal abundances for globular clusters using high dispersion spectra from both the old photographic and the most recent CCD data. The discrepant low abundances found by Cohen (1980), from photographic material for M71 giants, are found to be due to the use of too high microturbulences.


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