scholarly journals Vector Competence ofCulicoides sonorensis(Diptera: Ceratopogonidae) for Vesicular Stomatitis Virus

2005 ◽  
Vol 42 (3) ◽  
pp. 409-418 ◽  
Author(s):  
Barbara S. Drolet ◽  
Corey L. Campbell ◽  
Melissa A. Stuart ◽  
William C. Wilson
Keyword(s):  
Vesicular Stomatitis Virus ◽  
Vector Competence ◽  
Vesicular Stomatitis

scholarly journals Impacts of Infectious Dose, Feeding Behavior, and Age of Culicoides sonorensis Biting Midges on Infection Dynamics of Vesicular Stomatitis Virus

Pathogens ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 816
Author(s):  
Paula Rozo-Lopez ◽  
Berlin Londono-Renteria ◽  
Barbara S. Drolet
Keyword(s):  
Feeding Behavior ◽  
Vesicular Stomatitis Virus ◽  
Vector Competence ◽  
Blood Feeding ◽  
Whole Body ◽  
Biting Midges ◽  
Infectious Dose ◽  
Infection Dynamics ◽  
Culicoides Sonorensis ◽  
Vesicular Stomatitis

Culicoides sonorensis biting midges are biological vectors of vesicular stomatitis virus (VSV) in the U.S. Yet, little is known regarding the amount of ingested virus required to infect midges, nor how their feeding behavior or age affects viral replication and vector competence. We determined the minimum infectious dose of VSV-New Jersey for C. sonorensis midges and examined the effects of multiple blood-feeding cycles and age at the time of virus acquisition on infection dynamics. A minimum dose of 3.2 logs of virus/mL of blood resulted in midgut infections, and 5.2 logs/mL resulted in a disseminated infection to salivary glands. For blood-feeding behavior studies, ingestion of one or two non-infectious blood meals (BM) after a VSV infectious blood meal (VSV-BM) resulted in higher whole-body virus titers than midges receiving only the single infectious VSV-BM. Interestingly, this infection enhancement was not seen when a non-infectious BM preceded the infectious VSV-BM. Lastly, increased midge age at the time of infection correlated to increased whole-body virus titers. This research highlights the epidemiological implications of infectious doses, vector feeding behaviors, and vector age on VSV infection dynamics to estimate the risk of transmission by Culicoides midges more precisely.

626: Initial Experience with Vesicular Stomatitis Virus as a Treatment for Bladder Cancer

2006 ◽  
Vol 175 (4S) ◽  
pp. 202-202
Author(s):  
Sherwin Zargaroff ◽  
Yuancheng Wang ◽  
Xiayong Zheng ◽  
Jian Pu ◽  
Savio L. Woo ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Vesicular Stomatitis Virus ◽  
Initial Experience ◽  
Vesicular Stomatitis

Inhibition of Various Steps in the Replication Cycle of Vesicular Stomatitis Virus Contributes to Its Photoinactivation by AlPcS4 or Pc4 and Red Light

1999 ◽  
Vol 69 (3) ◽  
pp. 353 ◽  
Author(s):  
Anne C. E. Moor ◽  
Angeline E. Wagenaars-van Gompel ◽  
Ralph C. A. Hermanns ◽  
Jannes van der Meulen ◽  
Jolanda Smit ◽  
...  
Keyword(s):  
Vesicular Stomatitis Virus ◽  
Red Light ◽  
Replication Cycle ◽  
Vesicular Stomatitis
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