scholarly journals N-Methylpurine DNA Glycosylase and OGG1 DNA Repair Activities: Opposite Associations With Lung Cancer Risk

2012 ◽  
Vol 104 (22) ◽  
pp. 1765-1769 ◽  
Author(s):  
Yael Leitner-Dagan ◽  
Ziv Sevilya ◽  
Mila Pinchev ◽  
Ran Kramer ◽  
Dalia Elinger ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Dna Glycosylase ◽  
Methylpurine Dna Glycosylase

Joint Effects of Dietary Trace Metals and DNA Repair Capacity in Lung Cancer Risk

2007 ◽  
Vol 16 (12) ◽  
pp. 2756-2762 ◽  
Author(s):  
S. Mahabir ◽  
M. R. Forman ◽  
S. L. Barerra ◽  
Y. Q. Dong ◽  
M. R. Spitz ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Trace Metals ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Repair Capacity ◽  
Joint Effects ◽  
Dna Repair Capacity

DNA repair genes polymorphism and lung cancer risk with the emphasis to sex differences

2013 ◽  
Vol 40 (9) ◽  
pp. 5261-5273 ◽  
Author(s):  
L. Letkova ◽  
T. Matakova ◽  
L. Musak ◽  
M. Sarlinova ◽  
M. Krutakova ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Sex Differences ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Dna Repair Genes ◽  
Repair Genes

Elevated N3-methylpurine-DNA glycosylase DNA repair activity is associated with lung cancer

2012 ◽  
Vol 732 (1-2) ◽  
pp. 43-46 ◽  
Author(s):  
Philip A.J. Crosbie ◽  
Amanda J. Watson ◽  
Raymond Agius ◽  
Philip V. Barber ◽  
Geoffrey P. Margison ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Dna Glycosylase ◽  
Repair Activity ◽  
Methylpurine Dna Glycosylase

scholarly journals Genetic variant in DNA repair geneGTF2H4is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium

2016 ◽  
Vol 37 (9) ◽  
pp. 888-896 ◽  
Author(s):  
Meilin Wang ◽  
Hongliang Liu ◽  
Zhensheng Liu ◽  
Xiaohua Yi ◽  
Heike Bickeboller ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Large Scale ◽  
Genetic Variant ◽  
Lung Cancer Risk ◽  
Scale Analysis ◽  
Large Scale Analysis

scholarly journals Lung Cancer Risk and Genetic Polymorphisms in DNA Repair Pathways: A Meta-Analysis

2010 ◽  
Vol 2010 ◽  
pp. 1-17 ◽  
Author(s):  
Chikako Kiyohara ◽  
Koichi Takayama ◽  
Yoichi Nakanishi
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Genetic Polymorphisms ◽  
Lung Cancer Risk ◽  
Excision Repair ◽  
Meta Analysis ◽  
Epidemiologic Studies ◽  
Repair Capacity ◽  
Repair Pathways

Genetic variations in DNA repair genes are thought to modulate DNA repair capacity and are suggested to be related to lung cancer risk. We conducted a meta-analysis of epidemiologic studies on the association between genetic polymorphisms in both base excision repair and nucleotide excision repair pathways, and lung cancer. We found xeroderma pigmentosum complementation group A (XPA) G23A (odds ratio (OR)=0.76, 95% confidence interval (CI)=0.61–0.94), 8-oxoguanine DNA glycosylase 1 (OGG1) Ser326Cys (OR=1.22, 95% CI=1.02–1.45), and excision repair cross-complementing group 2 (ERCC2) Lys751Gln (OR=1.27, 95% CI=1.10–1.46) polymorphisms were associated with lung cancer risk. Considering the data available, it can be conjectured that if there is any risk association between a single SNP and lung cancer, the risk fluctuation will probably be minimal. Advances in the identification of new polymorphisms and in high-throughput genotyping techniques will facilitate the analysis of multiple genes in multiple DNA repair pathways. Therefore, it is likely that the defining feature of future epidemiologic studies will be the simultaneous analysis of large samples of cases and controls.

scholarly journals Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of Northern Spain

BMC Cancer ◽  
2007 ◽  
Vol 7 (1) ◽  
Author(s):  
M Felicitas López-Cima ◽  
Patricia González-Arriaga ◽  
Laura García-Castro ◽  
Teresa Pascual ◽  
Manuel G Marrón ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Dna Repair Genes ◽  
Northern Spain ◽  
Repair Genes

DNA repair gene XPD polymorphism and lung cancer risk: a meta-analysis

Lung Cancer ◽  
2004 ◽  
Vol 46 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Z. Hu ◽  
Q. Wei ◽  
X. Wang ◽  
H. Shen
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Meta Analysis ◽  
Repair Gene ◽  
Dna Repair Gene

scholarly journals Polymorphisms in DNA repair genes of XRCC1, XPA, XPC, XPD and associations with lung cancer risk in Chinese people

2014 ◽  
Vol 5 (3) ◽  
pp. 232-242 ◽  
Author(s):  
Chaorong Mei ◽  
Mei Hou ◽  
Shanxian Guo ◽  
Feng Hua ◽  
Dejie Zheng ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Dna Repair Genes ◽  
Chinese People ◽  
Repair Genes
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