Medications for Substance Use Disorders
Substance use disorder (SUD) is a chronic medical condition with relapses and remissions, and it has a strong genetic component. Risk for relapse increases with continued use because changes to the brain neurocircuitry pathways created by extensive substance use do not completely revert to normal after detoxification or stopping substance use. Medication-assisted treatment (MAT) is used for addiction to alcohol, opioids, or nicotine and is usually offered in combination with behavioral therapy and/or mutual support program participation. Medications can play a major role in facilitating initial abstinence, reducing relapse risk, and increasing the likelihood of the client maintaining longer periods of abstinence. Behavioral interventions can influence clients to use MAT in their recovery and influence adherence and impact on retention.