Breast Cancer Screening in Average-Risk Women

Author(s):  
Christoph I. Lee

This chapter, found in the cancer screening and management section of the book, provides a succinct synopsis of a key meta-analysis regarding the efficacy of mammography for breast cancer screening among younger and older average-risk women. This summary outlines study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. Meta-analysis of available trial data demonstrates a 15% mortality reduction among women aged 39 to 49 years with routine screening mammography. This age group has the highest rates of additional imaging but lowest rates of benign biopsy. In addition to outlining the most salient features of the analysis, a clinical vignette and imaging example are included in order to provide relevant clinical context.

2018 ◽  
Vol 206 (12) ◽  
pp. 931-934 ◽  
Author(s):  
Cristian Virgil Lungulescu ◽  
Cristina Lungulescu ◽  
Livia Teodora Lungulescu ◽  
Stefan-Alexandru Artene ◽  
Irina Mihaela Cazacu ◽  
...  

2007 ◽  
Vol 14 (5) ◽  
pp. 553-560 ◽  
Author(s):  
Dag Pavic ◽  
Michael J. Schell ◽  
Ria D. Dancel ◽  
Sanjeda Sultana ◽  
Li Lin ◽  
...  

2012 ◽  
Author(s):  
Gerald Gartlehner ◽  
Kylie Thaler ◽  
Dominik Berzaczy ◽  
Angela Kaminski ◽  
Andrea Chapman ◽  
...  

2017 ◽  
Vol 14 (9) ◽  
pp. 1137-1143 ◽  
Author(s):  
Debra L. Monticciolo ◽  
Mary S. Newell ◽  
R. Edward Hendrick ◽  
Mark A. Helvie ◽  
Linda Moy ◽  
...  

2017 ◽  
pp. 1-10 ◽  
Author(s):  
Elizabeth J. Siembida ◽  
Archana Radhakrishnan ◽  
Sarah A. Nowak ◽  
Andrew M. Parker ◽  
Craig Evan Pollack

Purpose Physician reminders have successfully increased rates of mammography. However, considering recent changes to breast cancer screening guidelines that disagree on the optimal age to start and stop mammography screening, we sought to examine the extent to which reminders have been deployed for breast cancer screening targeting younger and older patients. Methods A mailed survey was sent to a national sample of 2,000 primary care physicians between May and September 2016. Physicians were asked whether they received reminders to screen women in various age groups (40 to 44, 45 to 49, and ≥ 75 years), the organizational screening guidelines they trusted most, and whether they recommended routine breast cancer screening to average-risk women in the different age groups. Using regression models, we assessed the association between reminders and physician screening recommendations, controlling for physician and practice characteristics, and evaluated whether the association varied by the guidelines they trusted. Results A total of 871 physicians responded (adjusted response rate, 52.3%). Overall, 28.9% of physicians reported receiving reminders for patient ages 40 to 44 years, 32.5% for patient ages 45 to 49 years, and 16.5% for patient ages ≥ 75 years. Receiving reminders significantly increased the likelihood of physicians recommending mammography screening. In adjusted analyses, 84% (95% CI, 77% to 90%) of physicians who received reminders recommended screening for women ages ≥ 75 versus 65% (95% CI, 62% to 69%) of those who did not receive reminders. The associations between reminders and screening recommendations remained consistent regardless of which guidelines physicians reported trusting. Conclusion Reminders were significantly associated with increases in physician screening recommendations for mammography, underscoring the need for careful implementation in scenarios where guidelines are discordant.


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