breast cancer screening
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2022 ◽  
Vol 82 ◽  
pp. 224-227
Author(s):  
Ava Tsapatsaris ◽  
Kemi Babagbemi ◽  
Melissa B. Reichman

2022 ◽  
Author(s):  
Adam Yala ◽  
Peter G. Mikhael ◽  
Constance Lehman ◽  
Gigin Lin ◽  
Fredrik Strand ◽  
...  

Author(s):  
Ashley J. Housten ◽  
Diana S. Hoover ◽  
Maggie Britton ◽  
Therese B. Bevers ◽  
Richard L. Street ◽  
...  

Author(s):  
Ruiyang Zou ◽  
Sau Yeen Loke ◽  
Yew Chung Tang ◽  
Heng-Phon Too ◽  
Lihan Zhou ◽  
...  

Abstract Background Mammography is widely used for breast cancer screening but suffers from a high false-positive rate. Here, we perform the largest comprehensive, multi-center study to date involving diverse ethnic groups, for the identification of circulating miRNAs for breast cancer screening. Methods This study had a discovery phase (n = 289) and two validation phases (n = 374 and n = 379). Quantitative PCR profiling of 324 miRNAs was performed on serum samples from breast cancer (all stages) and healthy subjects to identify miRNA biomarkers. Two-fold cross-validation was used for building and optimising breast cancer-associated miRNA panels. An optimal panel was validated in cohorts with Caucasian and Asian samples. Diagnostic ability was evaluated using area under the curve (AUC) analysis. Results The study identified and validated 30 miRNAs dysregulated in breast cancer. An optimised eight-miRNA panel showed consistent performance in all cohorts and was successfully validated with AUC, accuracy, sensitivity, and specificity of 0.915, 82.3%, 72.2% and 91.5%, respectively. The prediction model detected breast cancer in both Caucasian and Asian populations with AUCs ranging from 0.880 to 0.973, including pre-malignant lesions (stage 0; AUC of 0.831) and early-stage (stages I–II) cancers (AUC of 0.916). Conclusions Our panel can potentially be used for breast cancer screening, in conjunction with mammography.


BMJ ◽  
2022 ◽  
pp. e065726
Author(s):  
Theodore Bartholomew ◽  
Mirela Colleoni ◽  
Harald Schmidt

2022 ◽  
pp. 104365962110668
Author(s):  
Cannas Kwok ◽  
Mi-Joung Lee ◽  
Chun Fan Lee

Introduction: Cultural beliefs are influential factors that affect breast cancer screening practices among Korean women. The aim of this study was to examine the role of educational levels and compare the cultural beliefs associated with breast cancer screening practices among immigrant Korean women in Australia with those of their counterparts in Korea. Methods: A secondary analysis based on data from convenience samples of 245 and 249 Korean women living in Australia and Korea, respectively. Data were collected by the Korean version of Breast Cancer Screening Beliefs Questionnaire. Results: Educational level has a significant association with Korean women’s cultural beliefs about breast cancer and breast cancer screening practices regardless of country of residence. Discussion: Nurses working in multicultural societies should take cultural beliefs and the role of education into account while designing strategies to promote breast cancer screening practices among immigrant Korean women.


2022 ◽  
Vol 35 (1) ◽  
pp. 77
Author(s):  
Sofia Cruz Neves ◽  
Arymar Júnior ◽  
Pedro Ferreira ◽  
Mafalda Albuquerque ◽  
Carlos Francisco Silva

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