Vibratory Medicine and Therapeutic Suspension Techniques

Author(s):  
Olivier Walusinski

Although the framework of neurological nosography was established during the second half of the nineteenth century, with Jean-Martin Charcot and his Salpêtrière School playing a major role, therapies for the recently identified diseases remained relatively ineffective. Since many Parkinson’s patients reported an improvement in their condition after being violently shaken during travel in mail carriages, Charcot recycled an old treatment method based on a vibratory armchair, assigning the preliminary study to Gilles de la Tourette, who tried to extend the technique to other pathologies by using a vibratory helmet. Another technique recommended by Charcot for treating tabes patients was “suspension,” thought to elongate the spinal cord. The related therapeutic tests in France and Europe are discussed in detail. Gilles de la Tourette made significant use of suspension at the time. The author compares his reports with the scientific challenges to his techniques and examines the resulting discussions.

2021 ◽  
Author(s):  
Penelope Pfeiffer ◽  
Joan R Coates ◽  
Andrew Kennedy ◽  
Kyleigh Getchell ◽  
Edina Kosa ◽  
...  

Blood-based biomarkers are much-needed diagnostic and prognostic tools for ALS. Canine degenerative myelopathy (DM) is recognized animal disease model to study the biology of human ALS. Serum derived exosomes are potential carrier that transport intercellular hormone-like messengers, together with their stability as carrier of proteins and RNA, make them ideal as biomarkers for a variety of diseases and biological processes. We study exosomal TDP-43 pattern as a surrogate biomarker that reflects biochemical changes in central nervous system. We isolated exosomes from canine serum using commercial exosome isolation reagents. TDP-43 and SOD1 profile in spinal cord homogenate lysate and that of serum-derived exosomes were found elevated in dogs with DM. We conclude levels of spinal cord TDP-43 and serum-derived exomes were similar in TDP-43 profiling, which warrant further investigation of disease sensitivity and specificity for establishing as a blood-based biomarker in canine DM.


2017 ◽  
Vol 9 (1) ◽  
pp. 69-85
Author(s):  
Márta Pintér

Abstract The present study adds to my ongoing research into Irish-Hungarian relations in the nineteenth century. As such it is concerned with Bertalan Szemere’s representation of Ireland in his travelogue Utazás külföldön [A Journey Abroad]. It approaches Szemere’s work from the perspective of the following three questions. How does Szemere’s trip to Ireland fit into the tradition of Irish-Hungarian contacts? What urged Szemere to sail over to Ireland and extend his already long and tiring tour of Europe? And finally, what factors shaped Szemere’s image of Ireland in his travel account? A preliminary study of the conditions of Szemere’s trip and his actual account of the country has led me to the hypothesis that in the process of creating his own representation of Ireland Szemere heavily relied on external sources. I seek to answer these questions by identifying the place of Szemere’s travel account in the tradition of Hungarian-Irish contacts; by relating it to other texts on Ireland by Szemere’s Hungarian contemporaries; and by comparing it to particular reports on Ireland by European travellers. My aim is to prove that Szemere’s representation of Ireland was primarily informed and moulded by German and English sources as they were transferred to Szemere by some Hungarian periodicals. My study also emphasizes the importance of further research into the interaction of Hungarian and European discourse on Ireland in the nineteenth century.


2001 ◽  
Vol 5 (1) ◽  
pp. 146-156
Author(s):  
Giuseppe Riva

The paper presents an overview of the ergonomic/design issues of a VR-enhanced orthopaedic appliance to be used in rehabilitation of patients with Spinal Cord Injury. First, some design considerations are described and an outline of aims which the tool should pursue are given. Finally, the design issues are described focusing both on the development of a test-bed rehabilitation device and on the description of a preliminary study detailing the use of the device with a long-term SCI patient. The basis for this approach is that physical therapy and motivation are crucial for maintaining flexibility and muscle strength and for reorganizing the nervous system after SCIs.


2019 ◽  
Vol 09 (03) ◽  
pp. 208-215
Author(s):  
Oumar Coulibaly ◽  
Mahamadou Dama ◽  
Oumar Diallo ◽  
Daouda Sissoko ◽  
Boubacar Sogoba ◽  
...  

Neuropeptides ◽  
2020 ◽  
Vol 79 ◽  
pp. 102000 ◽  
Author(s):  
Chuang Lyu ◽  
Sheng Xia ◽  
Gong-Wei Lyu ◽  
Xin-Peng Dun ◽  
Kang Zheng ◽  
...  

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