Spine

2021 ◽  
pp. 192-204
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Spinal Cord Injuries ◽  
Cord Compression ◽  
Practice Questions

This chapter contains practice questions based on a broad range of orthopaedic topics that may be encountered within the ‘Adult Pathology’ station of the FRCS (Trauma and Orthopaedics) viva examination. The spine topics covered include: spondylolisthesis, spinal cord compression, spinal cord injuries, and scoliosis as well as other conditions.

A remotely controlled model of spinal cord compression injury in mice: toward real-time analysis

2009 ◽  
Vol 11 (4) ◽  
pp. 461-470 ◽  
Author(s):  
Pascal Kouyoumdjian ◽  
Nicolas Lonjon ◽  
Monica Prieto ◽  
Henri Haton ◽  
Alain Privat ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Mr Imaging ◽  
Real Time ◽  
Spinal Cord Compression ◽  
Spinal Cord Injuries ◽  
Cord Compression ◽  
Genetically Engineered ◽  
In Vivo Studies ◽  
Compression Injury

Object To date, there has been no efficient therapeutic approach to spinal cord injuries (SCIs). This may be attributable, at least in part, to difficulties in forming predictive and accurate experimental animal models. The authors' previous studies have identified 2 relevant conditions of such a model. The first condition is the ability to compare data derived from rat models of SCI by developing mouse models of SCI that permit access to a large range of transgenic models. The second condition is that the exploration of the consequences of each mechanism of spinal trauma requires modeling the different etiologic aspects of the injury. Methods To fulfill these 2 conditions a new model of mouse spinal cord compression injury was devised using a thread-driven olive-shaped compressive device. The authors characterized early motor, sensory, and histological outcomes using 3 olive diameters and different compression durations. Results A gradual and reproducible functional severity that correlated with lesion extension was demonstrated in 76 mice. To further substantiate the characterization of this model, a noncompetitive N-methyl-d-aspartate antagonist was administered in 30 mice, which demonstrated the involvement of excitotoxicity in this model. Conclusions The study demonstrated that spinal olive-compression injury in the mouse is a reproducible, well-characterized, and predictable model for analyzing early events after SCI. The nonmagnetic and remotely controlled design of this model will allow completion of the lesion while the animal is in the MR imaging apparatus, thus permitting further real-time MR imaging studies that will provide insights into the characterization of early events in the spatial and temporal evolution of SCI. Moreover, this model lays the foundation for future in vivo studies of functional and histological outcomes following SCI in genetically engineered animals.

Evaluation of acute nonpenetrating cervical spinal cord injuries with CT metrizamide myelography

1985 ◽  
Vol 63 (4) ◽  
pp. 510-520 ◽  
Author(s):  
Robert L. Allen ◽  
Phanor L. Perot ◽  
Steven K. Gudeman
Keyword(s):  
Spinal Cord ◽  
Computerized Tomography ◽  
Spinal Cord Compression ◽  
Spinal Canal ◽  
Spinal Cord Injuries ◽  
Cervical Spinal Cord ◽  
Cord Compression ◽  
Surgical Decompression ◽  
Content Type ◽  
Fine Print

✓ Computerized tomography metrizamide myelography was performed in 46 patients with acute, nonpenetrating cervical spinal cord injuries. By visualizing the spinal canal, spinal cord, and any compressive lesion, the study proved valuable in the decision as to whether surgical decompression was indicated and what approach should be used. Eleven patients were found to have significant spinal cord compression, 10 of whom were treated surgically. The technique, results, and complications resulting from the study are discussed.

Spinal cord compression due to extramedullary hematopoiesis in beta-thalassemia

2020 ◽  
Vol 78 (10) ◽  
pp. 663-664
Author(s):  
Renan Ramon Souza LOPES ◽  
Larissa Soares CARDOSO ◽  
Franz ONISHI
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Beta Thalassemia

scholarly journals Is there a right time for surgery in paraplegic patients secondary to non traumatic spinal cord compression?

2012 ◽  
Vol 10 (4) ◽  
pp. 508-511 ◽  
Author(s):  
Leonardo Giacomini ◽  
Roger Neves Mathias ◽  
Andrei Fernandes Joaquim ◽  
Mateus Dal Fabbro ◽  
Enrico Ghizoni ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Prognostic Factor ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Lower Limbs ◽  
Motor Deficit ◽  
Indication For Surgery ◽  
Sensory Deficits ◽  
Sensory Involvement ◽  
Spinal Cord Decompression

Paraplegia is a well-defined state of complete motor deficit in lower limbs, regardless of sensory involvement. The cause of paraplegia usually guides treatment, however, some controversies remain about the time and benefits for spinal cord decompression in nontraumatic paraplegic patients, especially after 48 hours of the onset of paraplegia. The objective of this study was to evaluate the benefits of spinal cord decompression in such patients. We describe three patients with paraplegia secondary to non-traumatic spinal cord compression without sensory deficits, and who were surgically treated after more than 48 hours of the onset of symptoms. All patients, even those with paraplegia during more than 48 hours, had benefits from spinal cord decompression like recovery of gait ability. The duration of paraplegia, which influences prognosis, is not a contra-indication for surgery. The preservation of sensitivity in this group of patients should be considered as a positive prognostic factor when surgery is taken into account.

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