Sarcomas of soft tissue and bone

External Beam Therapy ◽

10.1093/med/9780198786757.003.0020 ◽

2019 ◽

pp. 454-467

Author(s):

James Wylie

Keyword(s):

Soft Tissue ◽

Chest Wall ◽

Palliative Treatment ◽

Soft Tissue Sarcomas ◽

Dose Fractionation ◽

Target Definition ◽

Patient Preparation ◽

Radiotherapy Techniques ◽

Hands And Feet

Chapter 20 covers sarcomas of soft tissue and bone and includes discussion of radiotherapy for soft tissue sarcomas (including indications for radiotherapy, essential investigations for planning radiotherapy, patient preparation, planning imaging required for target definition, target definition, dose fractionation, and critical organs and tolerance doses,including the sites forearm, hands and feet, retroperitoneum, chest wall, and spinal/para-spinal), particular histologies (angiosarcoma and fibromatosis), particular radiotherapy techniques, and palliative treatment (including cerebral and lung secondaries),

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Soft Tissue Sarcomas of the Extremities and Chest Wall

Surgery in Breast Cancer and Melanoma ◽

10.1007/978-1-84996-435-7_14 ◽

2010 ◽

pp. 229-246

Author(s):

Eugene A. Choi ◽

Raphael E. Pollock

Keyword(s):

Soft Tissue ◽

Chest Wall ◽

Soft Tissue Sarcomas

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The impact of 3D conformal radiotherapy versus intensity-modulated radiotherapy on post-operative wound complications in soft tissue sarcomas of the extremity and chest-wall

Journal of Radiation Oncology ◽

10.1007/s13566-016-0277-0 ◽

2016 ◽

Vol 5 (4) ◽

pp. 389-394 ◽

Cited By ~ 2

Author(s):

Hina Saeed ◽

Candice Johnstone ◽

David M. King ◽

John Charlson ◽

Donald A. Hackbarth ◽

...

Keyword(s):

Soft Tissue ◽

Chest Wall ◽

Soft Tissue Sarcomas ◽

Intensity Modulated Radiotherapy ◽

Conformal Radiotherapy ◽

Wound Complications ◽

Intensity Modulated ◽

3D Conformal Radiotherapy ◽

The Impact ◽

Operative Wound

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A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis®)

Case Reports in Oncology ◽

10.1159/000452147 ◽

2016 ◽

Vol 9 (3) ◽

pp. 655-660 ◽

Cited By ~ 1

Author(s):

Marco Rastrelli ◽

Saveria Tropea ◽

Romina Spina ◽

Alessandra Costa ◽

Roberto Stramare ◽

...

Keyword(s):

Soft Tissue ◽

Chest Wall ◽

Tissue Regeneration ◽

Soft Tissue Sarcomas ◽

Surgical Excision ◽

Smooth Muscle Tumor ◽

Chest Wall Resection ◽

En Bloc ◽

Dermal Matrix ◽

Treatment Protocols

Sarcomas arising from the chest wall account for less than 20% of all soft tissue sarcomas, and at this site, primitive tumors are the most frequent to occur. Leiomyosarcoma is a malignant smooth muscle tumor and the best outcomes are achieved with wide surgical excision. Although advancements have been made in treatment protocols, leiomyosarcoma remains one of the more difficult soft tissue sarcoma to treat. Currently, general local control is obtained with surgical treatment with wide negative margins. We describe the case of a 50-year-old man who underwent a chest wall resection involving a wide portion of the pectoralis major and minor muscle, the serratus and part of the second, third and fourth ribs of the left side. The full-thickness chest wall defect of 10 × 8 cm was closed using a non-cross-linked acellular dermal matrix (Egis®) placed in two layers, beneath the rib plane and over it. A successful repair was achieved with no incisional herniation and with complete tissue regeneration, allowing natural respiratory movements. No complications were observed in the postoperative course. Biological non-cross-linked matrix, derived from porcine dermis, behaves like a scaffold supporting tissue regeneration; it can be successfully used as an alternative to synthetic mesh for chest wall reconstruction.

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