History and examination

Author(s):  
Tim Raine ◽  
George Collins ◽  
Catriona Hall ◽  
Nina Hjelde ◽  
James Dawson ◽  
...  

This chapter discusses history and examination, including basic history and examination, recording your clerking, cardiovascular medicine, respiratory medicine, gastrointestinal medicine, neurological medicine, endocrine medicine, skin, oncological/haematological medicine, breast surgery, eye surgery, head and neck surgery, musculoskeletal surgery, urological surgery, the female reproductive system, obstetric medicine, psychiatric medicine, neonatal examination, and paediatrics.

Author(s):  
Tim Raine ◽  
James Dawson ◽  
Stephan Sanders ◽  
Simon Eccles

Basic historyBasic examinationRecording your clerkingMedicineCardiovascularRespiratoryGastrointestinalNeurologicalEndocrineSkinOncological/haematologicalSurgeryBreastEyesHead and neckMusculoskeletalUrologicalOther specialtiesFemale reproductive systemObstetricPsychiatricNeonatal examinationPaediatricTaking a thorough history is an essential skill as a junior doctor and something you will become extremely practised at. These two pages show the basic features of a history, with details of how to perform a basic examination following after. The rest of the chapter shows how to adapt these basic approaches for specific situations....


1972 ◽  
Vol 70 (2) ◽  
pp. 396-408 ◽  
Author(s):  
K.-D. Schulz ◽  
H. Haarmann ◽  
A. Harland

ABSTRACT The present investigation deals with the oestrogen-sensitivity of the female reproductive system during the neonatal period. Newborn female guinea pigs were used as test animals. At different times after a single subcutaneous injection of a physiological dose of 0.1 μg or an unphysiologically high dose of 10 μg 17β-oestradiol/100 g body weight, the RNA- and protein-synthesis was examined in the hypothalamic region, pituitary, cerebral cortex, liver, adrenal gland, ovary and uterus. With a physiological dose an increase in organ weight, protein content, RNA-and protein-synthesis was found only in the uterus. These alterations turned out to be dose-dependent. In addition to the findings in the uterus an inhibition of the aminoacid incorporation rate occurred in the liver following the injection of the high oestradiol dose. As early as 1 hour after the administration of 0.1 μg 17β-oestradiol an almost 100% increase in uterine protein synthesis was detectable. This result demonstrates a high oestrogen-sensitivity of this organ during the neonatal period. All the other organs of the female reproductive system such as the hypothalamus, pituitary and ovary did not show any oestrogen response. Therefore the functional immaturity of the uterus during post partem life is not the result of a deficient hormone sensitivity but is correlated with the absence of a sufficient hormonal stimulus at this time. The investigation on the effects of actinomycin resulted in different reactions in the uterus and liver. In contrast to the liver a paradoxical actinomycin effect was found in the uterus after treatment with actinomycin alone. This effect is characterized by a small inhibition of RNA-synthesis and a 50% increase in protein synthesis. The treatment of the newborn test animals with actinomycin and 17β-oestradiol together abolished the oestrogen-induced stimulation of the uterine RNA-and protein-synthesis. Consequently, the effect of oestrogens during the neonatal period is also connected with the formation of new proteins via an increased DNA-directed RNA-synthesis.


2017 ◽  
Vol 27 (3) ◽  
pp. 250-265 ◽  
Author(s):  
Volodymyr Yu. Prokopyuk ◽  
◽  
Olga V. Grischenko ◽  
Oleksandra V. Prokopyuk ◽  
Nadiia O. Shevchenko ◽  
...  

1987 ◽  
Vol 7 (3) ◽  
pp. 173-174
Author(s):  
Issei Ichimiya ◽  
Yuichi Kurono ◽  
Goro Mogi

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