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2022 ◽  
Author(s):  
Liliana Budevici-Puiu ◽  

Radical changes that take place in all society spheres (economic, social, political and cultural) of a state, directly and indirectly affect the development and functioning of the socio-economic system of physical culture and sports. A new category of human resources employed in the field of sports management is emerging, given that sports organizations are interested in forming a management system that ensures high performance, development opportunities and a stable market position. In the last decade, the system of physical culture and sports management has undergone substantial changes, as a result of the emergence of new sports events, the development of sports movement, the creation of innovative services and the production of special equipment / installations in accordance with the legislation in force, as well as due to modern trends in entrepreneurial activity in market conditions. The fulfillment of the management functions in these conditions, at a higher level, generator of performance and success can be ensured only by qualified persons who have received a special professional training (including additional, continuous training) and requalification. This training is necessary for all activities specific to the field of physical education and sports management, for the development and proper functioning of sports organizations. Management and marketing activities, innovative for physical culture and the national sports movement, require special knowledge, skills and an effective professional training of the specialists in the field.



2022 ◽  
Author(s):  
Pegah Sarraf ◽  
Razieh Sadat Moayeri ◽  
Noushin Shokouhinejad ◽  
Mehrfam Khoshkhounejad ◽  
Roya Karimi ◽  
...  

Abstract Background: PRF as one of the favorable scaffolds in Regenerative Endodontic Treatment (RET), has several limitations such as the need for blood sampling and special equipment. High available commercial scaffolds such as fibrin are able to meet all the necessary requirements of dentin tissue engineering. The present study was designed to evaluate the effect of PRF and fibrin gel, with and without the presence of EDTA-treated radicular dentin segments on SCAP viability, proliferation, migration, and differentiation.Methods: Radicular dentin were prepared from extracted teeth and treated by EDTA 17% .The samples were divided into 6 groups: Dentin/PRF/Cell, Dentin/Fibrin/Cell, Dentin/Cell, PRF/Cell, Fibrin/Cell and Cell (Control). SCAP viability was assessed using MTT assay. Gene expression levels of odontogenic markers [Dentin sialophosphoprotein (DSPP), Dentin matrix protein 1(DMP1), Collagen type I Alpha 1(COL 1A1) and Alkaline phosphatase (ALP) were assessed using qrt-PCR. Cell migration were also evaluated by means of scratch test. Results: The results of MTT assay at showed that the viability of SCAP significantly increased after 7 days for both groups containing fibrin (P <0.05). The viability of SCAP seeded on Dentin/PRF and PRF significantly decreased after 7 days (P <0.001). The odontogenic markers were significantly expressed for both scaffolds in the presence of dentin segment (p<0.05). Significant decrease in scratch area was seen in Fibrin/Dentin group (p < 0.001)Conclusions:Fibrin beside EDTA-treated dentin showed great ability in survival, proliferation, differentiation, and migration of SCAP rather than PRF.



2022 ◽  
Vol 3 (1) ◽  
pp. 07-12
Author(s):  
Lilik Mugiharto ◽  
Aries Sudiarso ◽  
Luhut Simbolon

Indonesia has the potential for a nuclear emergency, so it is necessary to prepare resources to deal with nuclear emergencies to minimize losses. A nuclear emergency caused by a nuclear reactor accident is a non-military defense sector as the main component supported by other elements of the nation's power. Nuclear Biology and Chemical Company of the Indonesian Armed Forces Army (Kizinubika) is another element of the nation's power that provides reinforcement in non-military defense in the face of nuclear emergencies. The purpose of this study is to strengthen the Kizinubika resources for the Nuclear Energy Supervisory Agency (Bapeten) and the Directorate for the Management of Nuclear Facilities at the National Research and Innovation Agency (DPFKN-BRIN) in dealing with nuclear emergencies in order to support national defense. This type of research is qualitative by using literature study, observation, and interview methods. Internal resource criteria are determined based on the Resources Based View (RBV) theory. The results of the study in the form of recommended resources in strengthening the Kizinubika against Bapeten and DPFKN-BRIN in the form of; (1) The use of the Kizinubika facility as a joint training facility and infrastructure; (2) The use of special equipment Kizinubika in support of nuclear emergency response; (3) Kizinubika's strategic location close to DPFKN-BRIN supports speed in emergency response; (4) Use of Kizinubika's Human Resources through joint training in increasing the quantity and quality of training; and (5) Kizinubika's internal organizational relations support the task of dealing with nuclear emergencies.



2022 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Nan Zhu ◽  
Kai He

<p style='text-indent:20px;'>The main objective of this research is to measure the efficiency of 397 major industrial enterprises in Sichuan province of China in 2013.To this end, we employed DEA super slacks-based measure (Super-SBM) model for performance evaluation of 397 major manufacturing firms.The empirical results show that 21 of the 397 enterprises operate efficiently, and the average efficiency score of the analyzed enterprises is only 0.15. The enterprise with the highest efficiency score is 96.15% higher than the average score, which is the benchmark enterprise of operational efficiency. Among the selected sample enterprises, 5.29% of the industrial enterprises are highly efficient in operation. It was also noticed that the average efficiency score of pharmaceutical firms was the highest among all industrial firms with a mean score of 0.75, which is 80% higher than the overall average score of all industries. While the average efficiency of manufacturing of chemical raw materials and chemical products was the lowest with a mean score of 0.39. Results of sensitivity analysis show that profit has a great impact on the efficiency score of special equipment manufacturing firms, but a relatively weak impact on the firms which manufacture computers, communications, and other electronic equipment. The effect of export delivery value on efficiency score is not obvious.</p>



Author(s):  
Nataliia Pysarska ◽  
Vitalii Iepifanov ◽  
Sergej Nazarenko

The review article systematizes information and studies the  history of designing tractors and prime-movers at the State Enterprise «Kharkiv Design Bureau for Mechanical Engineering named after A. A. Morozov» and their manufacture by the State Enterprise «Malyshev Plant » from the origin of such production in Kharkiv to the present time. The role of Kharkiv in providing the country with special equipment is revealed. Detailed biographical information about chief designers of this technique (B. N. Voronkov, N. G. Zubarev, M. N. Shchukin, A. I. Avtomonov, M. D. Borisyuk, A. D. Motrich, M. P. Kalugin, P. I. Sagir, B. I. Kalchenko) provided, their role in the development and improvement of designs of special-purpose machines is indicated. The main technical characteristics of basic models of tractors and prime-movers are presented. The main problems in the production of these types of equipment are mentioned. The article contains information about various modifications of AT-T, their main differences and purposes are indicated. Keywords: tractor, prime-mover, SE «Kharkiv Design Bureau of Engineering Named after A. A. Morozov», SE «Malyshev Plant», National Technical University «Kharkiv Polytechnic Institute»



Author(s):  
Lilia Dergaciova ◽  
Andrii Boiko-Haharin

During the past two decades, with the development of private search using a special equipment, the number of known coins has increased dramatically, opening up the new opportunities for researchers. The aim of the study. Some of these finds, mainly treasures, have been the subject of the specialized research or have been the part of various numismatic publications, which cannot be said of isolated finds that have only been partially covered in the scientific literature. At the same time, the individual finds are not inferior to informative treasures, allowing a reconstructing the monetary circulation of a single settlement or city, its economic potential, interregional trade relations and many other aspects that contribute together to the restoration of the historical past. Over the last 10-15 years, the authors of this article have been systematically collecting information about the medieval coins found in Ukraine, some of which have an exact location. Thus, the purpose of this article is the gradual introduction into scientific circulation of the numismatic material originating from the territory of modern Ukraine with its full description, illustrations and outlines, references to current works and catalogues. It opens a series of articles on issues of the XV and XVII centuries, namely the Moldavian coins of Alexander I the Good, Stephen III the Great and one piece of the crown solidus of Sigismund III, found with them. Within the 22 coins described in the article, about 10 were found: 6 coins originate from Chernivtsi region, 1 piece of Moldovan coins were founded in Vinnytsia, Poltava, Volyn and Lviv regions. Other coins were also found on the territory of modern Ukraine, the authors do not know the exact places of their discovery. The Conclusions. The topographic distribution of the finds indicates that the main zone of concentration of Moldavian coins falls on the Chernivtsi region, which is quite natural, given that these lands, mentioned in written sources under the name of Shipinska land (terra Sepenicensis), were was included the part of the Moldavian principality since the end of XIV century. The distribution of Moldovan coin finds in Ukraine corresponds to the same international trade routes that connected Central Europe with the Crimean Peninsula, passing through the territory of modern Ukraine and Moldova, known as «Tatar» and «Moldovan» trade routes; and the mediating the role played by the lands of the Principality of Moldavia in this trade.



Author(s):  
Andrey Nuzhdin

Crimes committed by convicts serving criminal punishments present an urgent social problem. Although inmates are isolated and under constant control, the number of penitentiary crimes is growing. The identification of the whole complex of circumstances contributing to penitentiary crimes and their elimination are a guarantee of successful work on preventing crimes of this type. The potential of modern achievements in science and technology should be actively used in preventive work. Many legal scholars stress that the possibilities of using technical means, techniques and methods in the process of preventing crime (including penitentiary crime) are undervalued. Employees of preliminary investigation bodies and penitentiary institutions, in their turn, do not give value to the technical-forensic support (and sometime do not simply understand its possibilities) of preventing penitentiary crime. At the same time, their high priority and value in the organization of preventive work is beyond doubt. The article describes the theoretical basis of using technical-forensic means, offers their classification, shows key spheres of their use. The author stresses the preventive potential of special equipment available in each correctional institution (technical means of security and supervision). The article presents and offers a detailed classification of technical-forensic means, techniques and methods of preventing penitentiary crimes.



Materials ◽  
2021 ◽  
Vol 15 (1) ◽  
pp. 38
Author(s):  
Faiza Safdar ◽  
Amjed Javid ◽  
Munir Ashraf

Synthesis and modification of nanoparticles to make them suitable to functionalise a substrate for various application fields involves many steps, which are complex, time-consuming, and sometimes require special equipment. This is a major drawback to meet rapid technological requirements. In this work, a procedure has been developed to modify TiO2 nanoparticles by the sol-gel method at their synthesis stage using titanium tetraisopropoxide and modifying agents including ODS and GPTMS. The prepared nanoparticle finish can be used as it is without any further processing, thus eliminating the need for extra steps required to decorate them on some substrate. The nanoparticles were characterised by SEM, EDX, FTIR, XRD, and zeta potential. The adhesion of the obtained nanoparticles was tested by applying them to a cellulosic substrate. The obtained substrate was subjected to mechanical action and adhesion efficiency was estimated on the basis of UV transmittance and antibacterial properties that showed excellent results. The hydrophobic properties of the obtained nanoparticles were assessed by measuring water contact angles, which reached 157.9°, indicating their superhydrophobic nature. The developed procedure is facile and will be suitable for the engineering of multiple surfaces.



Author(s):  
Наталия Александровна Полушкина ◽  
Наталия Владимировна Чиркова ◽  
Кристина Павловна Кубышкина ◽  
Татьяна Александровна Попова

Литературные данные за последнее десятилетие свидетельствуют о неуклонном росте количества больных, нуждающихся в съемных конструкциях зубных протезов. Адаптация пациентов к съемным пластиночным протезам, в особенности изготовленным из акриловой пластмассы, несомненно, является актуальной проблемой. Известно, что базис протеза изготовлен из материалов, не являющихся полностью биологически инертным веществом, а, следовательно, возможно их местное и общее воздействие на организм. В целях профилактики негативного действия съемных пластиночных протезов и улучшения качества протезирования многими исследователями были предложены различные способы, такие как уменьшение концентрации примесей, путем кипячения, применение СВЧ-полимеризации. Широкое применение получили эластичные материалы для изготовления базисов съемных протезов. Недостатком данных методов является то, что требуются наличие специального оборудования и материальных затрат как со стороны пациентов, так и стоматологических учреждений. В последние годы клиницистов привлекает возможность применения лекарственных препаратов для лечения и профилактики осложнений со стороны тканей протезного ложа. Идет постоянный поиск фармакологических средств, позволяющих оказывать противовоспалительное, противомикробное, антиаллергическое и иммуномодулирующeе действие. Перспективным направлением в профилактике осложнений является использование биорастворимых лекарственных пленок. Биорастворимая адгезивная плёнка имеет отличную особенность значительным противовоспалительным эффектом, подтверждаемым микробиологическими и клиническими показателями. Комплексное лечение заболеваний пародонта с применением рекомендуемой биорастворимой адгезивной плёнки позволит увеличить период ремиссии у пациентов с сахарным диабетом. Согласно последним данным доказано, что они нетоксичны, инертны для организма, пролонгируют действие биологически активных веществ, входящих в их состав. Таким образом, разработка биорастворимой адгезивной плёнки для профилактики и лечения местных осложнений со стороны слизистой оболочки протезного ложа у пациентов с сахарным диабетом 2-го типа, является на наш взгляд актуальным Iterature data over the past decade indicate a steady increase in the number of patients in need of removable denture structures. The adaptation of patients to removable plate prostheses, especially those made of acrylic plastic, is undoubtedly an urgent problem. It is known that the basis of the prosthesis is made of materials that are not completely biologically inert, and, therefore, their local and general effects on the body are possible. In order to prevent the negative effects of removable plate prostheses and improve the quality of prosthetics, many researchers have proposed various methods, such as reducing the concentration of impurities by boiling, the use of microwave polymerization. Elastic materials have been widely used for the manufacture of removable prosthesis bases. The disadvantage of these methods is that special equipment and material costs are required both from patients and dental institutions. In recent years, clinicians have been attracted by the possibility of using medications for the treatment and prevention of complications from the tissues of the prosthetic bed. There is a constant search for pharmacological agents that can provide anti-inflammatory, antimicrobial, antiallergic and immunomodulatory effects. A promising direction in the prevention of complications is the use of bio-soluble medicinal films. The bio-soluble adhesive film has an excellent feature of a significant anti-inflammatory effect, confirmed by microbiological and clinical indicators. Complex treatment of periodontal diseases with the use of the recommended bio-soluble adhesive film will increase the remission period in patients with diabetes mellitus. According to the latest data, it has been proven that they are non-toxic, inert to the body, prolong the action of biologically active substances that make up their composition. Thus, the development of a bio-soluble adhesive film for the prevention and treatment of local complications from the mucous membrane of the prosthetic bed in patients with type 2 diabetes mellitus is, in our opinion, relevant



2021 ◽  
Author(s):  
Katsuyuki Nakanishi ◽  
Munehisa Shinozaki ◽  
Narihito Nagoshi ◽  
Masaya Nakamura ◽  
Hideyuki Okano

Background: The spatial complexity of neuronal circuits in the central nervous system is an hurdle in understanding and treating brain and spinal cord injuries. Although several methods have recently been developed to render the spinal cord transparent and label specific neural circuits, three-dimensional visualization of long segments of spinal cord with high resolution remains challenging. New Method: We have established a method that combines tissue staining of neuronal tracts traced with biotinylated dextran amine (BDA) and a modified passive clarity clearing protocol. Results: BDA was injected into the unilateral sensorimotor cortex of a mouse model of thoracic spinal cord contusional injury. Ten days later, the spinal cord was removed and immersed first in staining solution and then in hydrogel solution. The spinal cord was then sealed with a syringe and underwent gelation process, followed by clearing with clearing solution and observation solution. Staining and clearing took a total of two weeks. The samples were observed with a lightsheet microscope, and three-dimensional reconstruction was performed with ImageJ software. With the lightsheet microscope, high resolution-images comparable with tissue sections were obtained continuously and circumferentially. By tiling, it was possible to obtain high-resolution images of long segments of the spinal cord, in which each fiber could be traced. The tissue could be easily re-stained in case of fading. Comparison with Existing Methods: The present method does not require special equipment, can label specific circuits without genetic technology, and re-staining rounds can be easily implemented. It enables to visualize specific neural circuit of long spinal cord segments with high resolution up to individual nerve fiber. Conclusions: By using simple neural labeling, staining, and transparency methods, it was possible to acquire a wide range of high-resolution three-dimensional images of the spinal cord.



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