Ulceration of the skin

Paediatric Dermatology ◽

10.1093/med/9780198821304.003.0030 ◽

2020 ◽

pp. 455-459

Keyword(s):

Pyoderma Gangrenosum ◽

Epidermolysis Bullosa ◽

Drug Reactions ◽

Genital Ulceration ◽

Goltz Syndrome ◽

Aplasia Cutis

This is a short chapter covering the causes of ulcers. The conditions are grouped into sections covering different aetiologies. Congenital conditions covered are epidermolysis bullosa, aplasia cutis, and Goltz syndrome. Infectious conditions are considered including bacterial, viral, and tropical ulcers. Traumatic ulcers including neuropathic and non-accidental causes are listed. There are further categories covering inflammation, including pyoderma gangrenosum, drug reactions, toxicity, and other causes. Oral and genital ulceration is sign-posted to the relevant chapters.

Download Full-text

Lipschütz Ulcer: An Unusual Diagnosis that Should Not be Neglected

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0041-1729147 ◽

2021 ◽

Vol 43 (05) ◽

pp. 414-416

Author(s):

Daniela Alexandra Gonçalves Pereira ◽

Eliana Patrícia Pereira Teixeira ◽

Ana Cláudia Martins Lopes ◽

Ricardo José Pina Sarmento ◽

Ana Paula Calado Lopes

Keyword(s):

Emergency Department ◽

Differential Diagnosis ◽

Clinical Course ◽

Malignant Tumors ◽

Sudden Onset ◽

Drug Reactions ◽

Genital Ulceration ◽

Sexually Transmitted ◽

Inflammatory Processes ◽

Genital Ulcers

AbstractThe diagnosis of genital ulcers remains a challenge in clinical practice. Lipschütz ulcer is a non-sexually transmitted rare and, probably, underdiagnosed condition, characterized by the sudden onset of vulvar edema along with painful necrotic ulcerations. Despite its unknown incidence, this seems to be an uncommon entity, with sparse cases reported in the literature. We report the case of an 11-year-old girl who presented at the emergency department with vulvar ulcers. She denied any sexual intercourse. The investigation excluded sexually transmitted infections, so, knowledge of different etiologies of non-venereal ulcers became essential. The differential diagnoses are extensive and include inflammatory processes, drug reactions, trauma, and malignant tumors. Lipschütz ulcer is a diagnosis of exclusion. With the presentation of this case report, the authors aim to describe the etiology, clinical course, and outcomes of this rare disease, to allow differential diagnosis of genital ulceration.

Download Full-text

Deletion of the first pair of fibronectin type III repeats of the integrin β-4 gene is associated with epidermolysis bullosa, pyloric atresia and aplasia cutis congenita in the original Carmi syndrome patients

American Journal of Medical Genetics Part A ◽

10.1002/ajmg.a.31903 ◽

2008 ◽

Vol 146A (8) ◽

pp. 1063-1066 ◽

Cited By ~ 19

Author(s):

Ramon Y. Birnbaum ◽

Daniella Landau ◽

Khalil Elbedour ◽

Rivka Ofir ◽

Ohad S. Birk ◽

...

Keyword(s):

Epidermolysis Bullosa ◽

Pyloric Atresia ◽

Aplasia Cutis Congenita ◽

Type Iii ◽

Fibronectin Type Iii ◽

Fibronectin Type ◽

Aplasia Cutis ◽

Carmi Syndrome

Download Full-text

Aplasia cutis congenita with dystrophic epidermolysis bullosa: Bart syndrome

Indian Journal of Dermatology Venereology and Leprology ◽

10.4103/ijdvl.ijdvl_1094_19 ◽

2020 ◽

Vol 0 (0) ◽

pp. 0

Author(s):

XingHua Gao ◽

Liang Zhang ◽

XueGang Xu ◽

Chao Zhang ◽

Jie Qin

Keyword(s):

Epidermolysis Bullosa ◽

Dystrophic Epidermolysis Bullosa ◽

Aplasia Cutis Congenita ◽

Aplasia Cutis

Download Full-text

Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges

Case Reports in Pediatrics ◽

10.1155/2019/2459219 ◽

2019 ◽

Vol 2019 ◽

pp. 1-5

Author(s):

Rebecca J Calthorpe ◽

Emma Spencer ◽

Jane C Ravenscroft ◽

Ting S Tang ◽

Anna E Martinez ◽

...

Keyword(s):

Differential Diagnosis ◽

Herpes Simplex Virus ◽

Herpes Simplex ◽

Epidermolysis Bullosa ◽

Herpes Simplex Virus Type ◽

Rare Case ◽

Preterm Neonate ◽

Skin Loss ◽

Simplex Virus ◽

Aplasia Cutis

We describe a rare case of a preterm neonate presenting at birth with extensive epidermal skin loss of over 90% due to disseminated herpes simplex virus type one infection. Differential diagnosis included aplasia cutis and epidermolysis bullosa. Serum PCR and mouth swabs confirmed HSV type one, and the patient required three weeks of treatment with intravenous aciclovir, followed by oral aciclovir. We describe the management challenges and give practical solutions applicable to the care of a neonate presenting with widespread skin loss due to any aetiology.

Download Full-text