Background diabetic retinopathy

Author(s):  
Rachel Stockwin ◽  
Emma Shepherd

Background diabetic retinopathy (DR) can involve several different microvascular pathologies, which will be explained with example images. These include microaneurysms, haemorrhages, exudates, cotton wool spots, and venous loops. The reader will learn how these features relate to the grading and referral criteria. This chapter aims to provide information on how these pathologies develop and why it is important that they are recognized in the earlier stages of background DR. The chapter will demonstrate how ischaemia can affect the capillary network and also how related conditions, such as hypertension and blood glucose, can contribute to vascular changes. In addition, this chapter will explain how to differentiate normal variants from DR changes.

Background diabetic retinopathy (DR) can involve several different microvascular pathologies, which will be explained with example images. These include microaneurysms, haemorrhages, exudates, cotton wool spots, and venous loops. The reader will learn how these features relate to the grading and referral criteria. This book aims to provide information on how these pathologies develop and why it is important that they are recognized in the earlier stages of background DR. It will demonstrate how ischaemia can affect the capillary network and also how related conditions, such as hypertension and blood glucose, can contribute to vascular changes. In addition, this book will explain how to differentiate normal variants from DR changes.


2021 ◽  
pp. 247412642198957
Author(s):  
Halward M.J. Blegen ◽  
Grant A. Justin ◽  
Bradley A. Bishop ◽  
Anthony R. Cox ◽  
James K. Aden ◽  
...  

Purpose: This work reports the association of obstructive sleep apnea (OSA) and cotton-wool spots (CWS) seen in patients with nonproliferative diabetic retinopathy (DR). Methods: A random sample of patients diagnosed with DR between January 1, 2015 and December 31, 2018, were selected from medical-billing codes. Dilated funduscopic examination findings and medical history were analyzed by reviewing medical records. Results: CWS were present in 12 of 118 patients without OSA, compared with 11 of 32 patients with OSA (10.2% vs 34.4%, respectively; P = .002). OSA was more common in men (68.8%, P = .03) and associated with a higher body mass index (30.0 ± 5.0 without OSA vs 33.6 ± 5.5 with OSA, P < .001). When comparing those with and without OSA, there was no association with age; glycated hemoglobin A1c; stage of DR; insulin dependence; presence of diabetic macular edema; smoking status; or a history of hypertension, hyperlipidemia, cardiovascular disease, or other breathing disorder. Conclusions: The presence of OSA is associated with CWS in patients with DR, as well as male sex and a higher body mass index. Further research is needed to determine the ophthalmologist’s role in the timely referral of patients with CWS for OSA evaluation.


1986 ◽  
Vol 70 (10) ◽  
pp. 772-778 ◽  
Author(s):  
M S Roy ◽  
M E Rick ◽  
K E Higgins ◽  
J C McCulloch

2020 ◽  
Vol 40 (7) ◽  
pp. 1625-1640 ◽  
Author(s):  
Amir Mahdjoubi ◽  
Youcef Bousnina ◽  
Gaelle Barrande ◽  
Faïza Bensmaine ◽  
Sadri Chahed ◽  
...  

2007 ◽  
Vol 48 (5) ◽  
pp. 2260 ◽  
Author(s):  
Meindert Niemeijer ◽  
Bram van Ginneken ◽  
Stephen R. Russell ◽  
Maria S. A. Suttorp-Schulten ◽  
Michael D. Abra`moff

2019 ◽  
Vol 8 (3) ◽  
pp. 4472-4475

Diabetes is a disorder that occurs when blood sugar level increases. Further increase of blood glucose lead to serious complications and it will affect major organs of our body. Diabetes affects both of the eyes called Diabetic Retinopathy (DR). If it is treated properly eye blindness can be prevented. The main objective of this paper is to detect Cotton Wool Spots (CWS) using morphological operations and the spots are segmented using k-means segmentation. Distinct features are extracted from the segmented image to train and test the Support Vector Machine (SVM) classifier. It is used to classify the lesions and the stages of diabetic retinopathy. It is noticed that sensitivity is 95% and the specificity is 86%.


Diabetes ◽  
1969 ◽  
Vol 18 (10) ◽  
pp. 691-704 ◽  
Author(s):  
E. M. Kohner ◽  
C. T. Dollery ◽  
C. J. Bulpitt

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