Extrinsic allergic alveolitis

2010 ◽  
pp. 3434-3446
Author(s):  
D.J. Hendrick ◽  
G.P. Spickett

Extrinsic allergic alveolitis is an uncommon inflammatory disorder of the lungs that results from hypersensitivity responses to inhaled environmental agents. Most varieties are occupational in origin, but sporadic cases arise in domestic settings or from recreational activities. Causal agents chiefly comprise allergenic microbial spores that contaminate stored vegetable produce (e.g. farmer’s lung caused by ...

1971 ◽  
Vol 88 (14) ◽  
pp. 346-351 ◽  
Author(s):  
H. Pirie ◽  
C. Dawson ◽  
R. Breeze ◽  
A. Wiseman ◽  
J. Hamilton

PEDIATRICS ◽  
1987 ◽  
Vol 79 (6) ◽  
pp. 1027-1029
Author(s):  
STEPHEN J. WOLF ◽  
ALLAN STILLERMAN ◽  
MILES WEINBERGER ◽  
WILBUR SMITH

Chronic interstitial lung disease is an uncommon clinical entity in childhood. The onset is frequently insidious with progressive tachypnea, dyspnea, cyanosis, clubbing, weight loss, and hypoxia. More than 100 different occupational and environmental agents have been identified as causes, although two thirds of cases are reported as idiopathic.1 Assessment can involve invasive procedures such as bronchoalveolar lavage and open lung biopsy. Treatment of the idiopathic forms includes use of corticostenoids and cytotoxic agents, and response is variable with progression to pulmonary fibrosis being a common end stage. In contrast to this grim prognosis, the similar clinical pattern associated with hypersensitivity pneumonitis, also identified as "extrinsic allergic alveolitis," can be rapidly reversed if the offending antigen is identified and eliminated.


2021 ◽  
Vol 7 (3) ◽  
pp. 152
Author(s):  
Catur Agustiyanto ◽  
Ariani Permatasari

Occupational lung disease is a lung disease or disorder that occurs due to the inhalation of dangerous particles, mist, vapors, or gases while a person is working. The materials accumulate in the respiratory tract or lungs. The type of lung disease that occurs depends on the size and type of the inhaled material. Substances that cause occupational lung disease are toxic materials called noksa. Noksa is a substance that can cause damage to the anatomical structure of body organs and cause respiratory tract function disorders. The lung disease that many farmers experience is often called farmer's lung disease (FLD). FLD is part of hypersensitivity pneumonitis (HP). HP, also known as extrinsic allergic alveolitis, is a group of lung diseases caused by the inhalation of various antigenic organic materials. The most common cause is exposure to agricultural biological dust derived from straw, mold spores, or other dust. HP can be a secondary reaction due to repeated and prolonged inhalation of specific antigens in sensitive individuals. Diagnosis of FLD is often inaccurate. Many of these cases are diagnosed as idiopathic interstitial lung disease. A complete anamnesis should be performed, especially regarding the history of exposure to moldy hay, previous work, and domestic animals, to determine the existence of a history of exposure to the antigen and to confirm the diagnosis.


1982 ◽  
Vol 27 (2) ◽  
pp. 154-157
Author(s):  
I. M. MacLeod ◽  
W. Rhind Brown

Two cases are described of the development of an allergic alveolitis in women working with straw as a packing material in an iron foundry. The clinical picture and results of investigations supported a diagnosis of farmer's lung qualifying the patients for payment of industrial disablement benefit.


1999 ◽  
Vol 37 (4) ◽  
pp. 285-289 ◽  
Author(s):  
V. Filipello Marchisio ◽  
F. Sulotto ◽  
G. C. Botta ◽  
A. Chiesa ◽  
D. Airaudi ◽  
...  

1975 ◽  
Vol 74 (1) ◽  
pp. 35-41 ◽  
Author(s):  
M. R. Hollingdale

SUMMARYA serological analysis of mycelial antigens ofThermoactinomyces vulgarisin immunodiffusion with human sera revealed five individual antigens. Three antigens were proteins, sensitive to pronase and soluble in phenol. Two were cationic polysaccharides, sensitive to sodium periodate, and containing glucosamine and muramic acid.Latex coated with mycelial antigens was compared with precipitin tests in detecting antibodies toT. vulgaris;the number of positive results detected by each test differed slightly, and a combination of the two tests detected the highest number. Counterimmunoelectrophoresis (CIE) was shown to be a very sensitive method for detecting precipitins, but not for their measurement. A prospective evaluation of immunodiffusion, latex agglutination and CIE as potential serodiagnostic techniques for farmer's lung disease is suggested.


1993 ◽  
Vol 14 (01) ◽  
pp. 31-37 ◽  
Author(s):  
Yvon Cormier ◽  
Michel Laviolette

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