Autoimmune skin disorders

Author(s):  
Gavin P Spickett

Overview Bullous pemphigoid Herpes gestationis and cicatricial pemphigoid Pemphigus vulgaris Pemphigus foliaceus Paraneoplastic pemphigus Epidermolysis bullosa acquisita Dermatitis herpetiformis (DH) and linear IgA disease Erythema multiforme (EM) Stevens–Johnson syndrome (SJS); toxic epidermal necrolysis (TEN) Sweet’s syndrome (acute febrile neutrophilic dermatosis) Lichen planus (LP) Alopecia areata...

2013 ◽  
Vol 88 (4) ◽  
pp. 672-675 ◽  
Author(s):  
Nurimar Conceicao Fernandes ◽  
Mariana Menezes

In this study, five cases of pemphigus vulgaris and two cases of pemphigus foliaceus were treated with cyclophosphamide pulse therapy associated with prednisone, resulting in the need for a smaller maintenance dose of prednisone. In three cases of pemphigus vulgaris and one case of pemphigus foliaceus, dexamethasone and cyclophosphamide pulse therapy associated with prednisone helped the lesions to heal more rapidly. Neither treatment however prevented the recurrence of the disease. Amenorrhea, myelotoxicity and Stevens-Johnson syndrome were among the cyclophosphamide side effects. All the patients treated with prednisone experienced known side effects.


Ophthalmology ◽  
2014 ◽  
Vol 121 (1) ◽  
pp. 79-87 ◽  
Author(s):  
Samer N. Arafat ◽  
Ana M. Suelves ◽  
Sandra Spurr-Michaud ◽  
James Chodosh ◽  
C. Stephen Foster ◽  
...  

1979 ◽  
Vol 87 (6) ◽  
pp. 734-740 ◽  
Author(s):  
Richard A. Chole ◽  
George H. Domb

Superficial ulcerations of the oral mucosa often present a diagnostic challenge to the physician because of the similarity of one ulcer to another. A diagnosis is made by the analysis of multiple factors, including the lesion's location, size, grouping, onset, patient's age, involvement of other systems of the body, and course of the disease. The histopathology of the lesion may be specific, especially in certain potentially fatal diseases. This paper presents the means for the differential diagnosis of a variety of superficial ulcers of the oral mucosa: varicella, herpangina, recurrent aphthous stomatitis, Behcet's disease, Stevens-Johnson syndrome, traumatic ulcer, verrucous carcinoma, primary herpetic gingivostomatitis, recurrent herpetic stomatitis, pemphigus vulgaris, and benign mucous membrane pemphigoid.


1980 ◽  
Vol 17 (3) ◽  
pp. 257-281 ◽  
Author(s):  
D. W. Scott ◽  
M. J. Wolfe ◽  
C. A. Smith ◽  
R. M. Lewis

In a review of non-viral bullous skin diseases of domestic animals and a 4-year study of cases presented to the New York State College of Veterinary Medicine, we found 15 diseases: pemphigus vulgaris, pemphigus vegetans, pemphigus foliaceus, pemphigus erythematosus, bullous pemphigoid, systemic lupus erythematosus, dermatitis herpetiformis, toxic epidermal necrolysis, drug eruption, epidermolysis bullosa, epidermolysis bullosa simplex, familial acantholysis, bovine congenital porphyria, impetigo and subcorneal pustular dermatosis. The 15 diseases were placed in five categories: autoimmune, immune-mediated, hereditary, bacterial and idiopathic. A histologic classification of these disorders based on the site of blister formation and other important clinicopathologic, histologic and immunopathologic findings was developed.


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