Compression neuropathies
Nerve compression disorders affect nerve trunks, particularly in the upper extremity where carpal tunnel syndrome (median nerve compression at the wrist) is the most common and ulnar nerve compression the second most common disorder. Compression affects the various components of the nerve trunk, including the intraneural blood vessels, the Schwann cells, the axons, and the connective tissue components. It results in sensory and motor dysfunction, and sometimes pain. Risk factors for nerve compression disorders are known and may predict surgical outcome. A careful clinical examination should always be done, sometimes complemented with appropriate electrophysiology and magnetic resonance imaging for diagnosis. If conservative treatment is not appropriate, or fails, simple decompression is generally the primary treatment, but problems may persist. The presence of other neuropathies should be considered.