Case 2.25

Author(s):  
Christine U. Lee ◽  
James F. Glockner

60-year-old woman with chronic liver disease Axial diffusion-weighted image (b=100 s/mm2) (Figure 2.25.1) demonstrates a mildly irregular hepatic contour with parenchymal nodularity and a hyperintense lesion in the medial left lobe. The IP and OP T1-weighted 2D SPGR images (...

2015 ◽  
Vol 41 (1) ◽  
pp. 56-62 ◽  
Author(s):  
Aysegul Sagir Kahraman ◽  
Bayram Kahraman ◽  
Zeynep Maras Ozdemir ◽  
Cemile Ayse Gormeli ◽  
Fatih Ozdemir ◽  
...  

2016 ◽  
Vol 46 (11) ◽  
pp. 2036-2042 ◽  
Author(s):  
Tatiane Cargnin Faccin ◽  
Glaucia Denise Kommers ◽  
Glauco José Nogueira de Galiza ◽  
Rayane Chitolina Pupin ◽  
Renata Cunha Madureira ◽  
...  

ABSTRACT: One hundred and ninety livers condemned due to chronic disease (fibrosis) were evaluated in a bovine slaughterhouse over 12 months. Hepatic lymph nodes were also examined while still attached to livers. The major macroscopic lesion observed in the livers was moderate to severe atrophy of the left lobe associated with compensatory hypertrophy of the right lobe. Histologically, the main changes corresponded to sites of macroscopic lesions, and fibrosis was observed in all livers, along with bile duct hyperplasia and neovascularization. Masson's trichrome stain highlighted the fibrous connective tissue. Most of the livers analyzed had macrophages with foamy cytoplasm and a peripheral nucleus that infiltrated fibrotic areas. Immunohistochemistry (IHC) for macrophages with monoclonal antibody clone MAC 387 revealed that the cytoplasm of the foamy macrophages of the liver and of the hepatic lymph nodes were positively immunostained. These cells are frequently associated to the consumption of grasses of the genus Brachiaria. Although the liver gross lesions described in this study have not been previously reported in animals consuming Brachiaria , the associated changes observed histologically, such as fibrosis and infiltration of foamy macrophages, showed a new form of chronic liver disease probably associated with the consumption of this forage. The IHC technique was important to prove that the foam cells observed are macrophages.


Radiology ◽  
2015 ◽  
Vol 277 (1) ◽  
pp. 309-309 ◽  
Author(s):  
Jiyoung Hwang ◽  
Young Kon Kim ◽  
Woo Kyoung Jeong ◽  
Dongil Choi ◽  
Hyunchul Rhim ◽  
...  

Author(s):  
Christine U. Lee ◽  
James F. Glockner

62-year-old woman with ADPKD and new onset anorexia, weight loss, night sweats, and fever Coronal SSFP (Figure 7.6.1) and axial fat-suppressed SSFP (Figure 7.6.2) images reveal enlarged, polycystic kidneys. There is a relatively hypointense mass in the lower pole of the left kidney. Axial diffusion-weighted image (b=800 s/mm...


Author(s):  
Christine U. Lee ◽  
James F. Glockner

42-year-old woman with a congenital disorder Axial fat-suppressed T2-weighted FSE (Figure 2.32.1) and 3D SSFP (Figure 2.32.2) images demonstrate hepatomegaly with innumerable diffuse microcysts throughout the liver. Axial diffusion-weighted image (b=100 s/mm2) (Figure 2.32.3) also shows hepatomegaly and a lobulated hepatic contour, and an axial postgadolinium portal venous phase 3D SPGR image (...


Radiology ◽  
2015 ◽  
Vol 276 (1) ◽  
pp. 137-146 ◽  
Author(s):  
Jiyoung Hwang ◽  
Young Kon Kim ◽  
Woo Kyoung Jeong ◽  
Dongil Choi ◽  
Hyunchul Rhim ◽  
...  

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