Effect of fish oil in a patient with post‐transplantation IgA nephropathy

2000 ◽  
Vol 15 (8) ◽  
pp. 1264-1265 ◽  
Author(s):  
Lavjay Butani ◽  
Joann Palmer
Keyword(s):  
Fish Oil ◽  
Iga Nephropathy ◽  
Post Transplantation

scholarly journals Immunoglobulin A (IgA) Nephropathy in Protocol Graft Kidney Biopsy done at six months Post Transplantation in a Tertiary Care Center Hospital of Nepal

2017 ◽  
Vol 6 (1) ◽  
pp. 6-11
Author(s):  
Midhan Shrestha ◽  
Dibya Singh Shah
Keyword(s):  
Iga Nephropathy ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
University Teaching ◽  
Time Interval ◽  
Post Transplantation ◽  
Protocol Biopsy ◽  
Post Transplant

Background: Renal transplantation is the treatment of choice for end stage renal disease. The focus of interest has been to increase the life of the transplanted graft. Recurrence of native kidney disease or occurrence of denovo glomerulonephritis has adverse effects in graft survival. Protocol graft biopsy done at fixed time interval after transplantation aids in early identification of post-transplant glomerulonephritis before development of clinical signs and symptoms. This study describes the incidence of post-transplant IgA Nephropathy in protocol renal graft biopsies done at six months post- transplantation.Materials and Methods: This is a hospital based observational descriptive study, done in Tribhuvan University Teaching Hospital, Kathmandu, Nepal, a tertiary medical referral center in the capital. Protocol biopsy of the graft kidney was performed at six months post-transplantation in all recipients who underwent kidney transplantation in this hospital between 2071 Kartik and 2072 Ashwin.Results: Protocol biopsy was performed in total 47 recipients. Mean age of the recipients was 33.7 years ±10.83 years. The study population consisted of 33 (70.2%) male and 14 (29.8%) female recipients. IgA Nephropathy was present in 6 (12.8%) recipients.Conclusion: Our study demonstrates that IgA Nephropathy does occur in patients with stable GFR and without any clinical or laboratory abnormalities. Protocol biopsy is valuable in detection of early histologic abnormalities before onset of clinical manifestations, thus helping in prompt management with aim to prolong the graft survival.Journal of Nobel Medical CollegeVolume 6, Number 1, Issue 10 (January-June, 2017)

Fish Oil for IgA Nephropathy?

1994 ◽  
Vol 331 (18) ◽  
pp. 1227-1229 ◽  
Author(s):  
Charles van Ypersele de Strihou
Keyword(s):  
Fish Oil ◽  
Iga Nephropathy

scholarly journals Fish oil therapy for IgA nephropathy: efficacy and interstudy variability.

1997 ◽  
Vol 8 (11) ◽  
pp. 1739-1744 ◽  
Author(s):  
J J Dillon
Keyword(s):  
Renal Function ◽  
Fish Oil ◽  
Iga Nephropathy ◽  
Medical Literature ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Immunoglobulin A ◽  
Sample Size Calculation ◽  
Positive Effects ◽  
Negative Results

Published reports examining the efficacy of fish oil for preserving renal function in immunoglobulin A (IgA) nephropathy have yielded conflicting results. This investigation was a meta-analysis conducted to determine whether the medical literature supports this therapy. In addition, the sources of variability among published findings were examined. Studies were combined using a random effects model. Five controlled studies were identified, two with positive results and three with negative results. Forty-four percent of the between-study variance could be attributed to differences in follow-up times and, less significantly, the number of renal function measurements; a weighting procedure was developed, eliminating this variance from the combined result. When all studies were combined, the mean effect, +0.25 +/- 0.23 SD (positive effects indicate that treatment was superior to control), was not statistically significant; however, the probability of at least a minor beneficial effect was 75%. Mixed-effects regression suggested that this therapy may be more effective among individuals with more proteinuria. The medical literature, therefore, does not prove the efficacy of fish oil therapy in IgA nephropathy, but suggests that an additional placebo-controlled trial is warranted. A sample-size calculation indicated that such a trial should be larger than those to date or should attempt to increase the treatment effect, perhaps by treating for more than 2 yr or enrolling more severely proteinuric individuals.

A Controlled Trial of Fish Oil in IgA Nephropathy

1994 ◽  
Vol 331 (18) ◽  
pp. 1194-1199 ◽  
Author(s):  
James V. Donadio ◽  
Erik J. Bergstralh ◽  
Kenneth P. Offord ◽  
Dorothy C. Spencer ◽  
Keith E. Holley
Keyword(s):  
Fish Oil ◽  
Iga Nephropathy ◽  
Controlled Trial

Specific management of IgA nephropathy: role of fish oil

Nephrology ◽  
2006 ◽  
Vol 11 ◽  
pp. S137-S140
Author(s):  
Merlin Thomas
Keyword(s):  
Fish Oil ◽  
Iga Nephropathy ◽  
Specific Management

Dietary fish oil supplementation in IgA nephropathy: A therapy in search of a mechanism?

Nutrition ◽  
1998 ◽  
Vol 14 (2) ◽  
pp. 240-242 ◽  
Author(s):  
Joseph P. Grande ◽  
James V. Donadio
Keyword(s):  
Fish Oil ◽  
Iga Nephropathy ◽  
Dietary Fish ◽  
Fish Oil Supplementation

Angiotensin Antagonists and Fish Oil for Treating IgA Nephropathy

2007 ◽  
pp. 27-36
Author(s):  
R. Coppo ◽  
A. Amore ◽  
L. Peruzzi ◽  
D. Mancuso ◽  
R. Camilla
Keyword(s):  
Fish Oil ◽  
Iga Nephropathy
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