scholarly journals Dual blockade of the renin-angiotensin system: are two better than one?

2009 ◽  
Vol 24 (12) ◽  
pp. 3602-3607 ◽  
Author(s):  
R. Haynes ◽  
P. Mason ◽  
K. Rahimi ◽  
M. J. Landray
2013 ◽  
Vol 1 (1) ◽  
pp. 18-20
Author(s):  
Eqerem Hasani ◽  
Alma Idrizi ◽  
Myftar Barbullushi

Aim: Aim of the study was the evaluation of the effect of dual blockade of the renin-angiotensin system (RAS) on proteinuria. Material and Methods: Sixty patients, included in the study, were treated with angiotensin-converting enzyme inhibitor and angiotensin receptor blocker for a period of 3 months. Results: The dual blockade of RAS resulted with decrease of proteinuria, a slight increase of serum creatinine and was not associated with a lowering of blood pressure.Conclusion: Combined therapy with ACE-I and ARB results in a more complete blockade of the RAS than monotherapy. In proteinuric nephropathies it reduces significantly baseline proteinuria.


BMJ ◽  
2001 ◽  
Vol 322 (7295) ◽  
pp. 1183-1183 ◽  
Author(s):  
J. McCormack

2019 ◽  
Vol 4 (7) ◽  
pp. S161 ◽  
Author(s):  
D. Lennartz ◽  
T. RAUEN ◽  
C. Fitzner ◽  
F. Eitner ◽  
R.D. Hilgers ◽  
...  

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