EAPH-16. DISCOVERY OF CT-179: A SMALL MOLECULE INHIBITOR OF THE OLIG2 TRANSCRIPTION FACTOR WITH POTENT ANTI-TUMOR IN PEDIATRIC BRAIN CANCER

Molecule Inhibitor ◽

Pediatric Brain

Corrigendum to: “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131]

EBioMedicine ◽

10.1016/j.ebiom.2017.10.029 ◽

2017 ◽

Vol 25 ◽

pp. 188

Author(s):

Anuradha Illendula ◽

Jane Gilmour ◽

Jolanta Grembecka ◽

Venkata Sesha Srimath Tirumala ◽

Adam Boulton ◽

...

Keyword(s):

Transcription Factor ◽

Small Molecule ◽

1-Benzyl-indole-3-carbinol is a highly potent new small molecule inhibitor of Wnt/β-catenin signaling in melanoma cells that coordinately inhibits cell proliferation and disrupts expression of microphthalmia-associated transcription factor isoform-M

Carcinogenesis ◽

10.1093/carcin/bgx103 ◽

2017 ◽

Vol 38 (12) ◽

pp. 1207-1217 ◽

Cited By ~ 5

Author(s):

Aishwarya Kundu ◽

Michelle G Khouri ◽

Sheila Aryana ◽

Gary L Firestone

Keyword(s):

Cell Proliferation ◽

Transcription Factor ◽

Small Molecule ◽

Melanoma Cells ◽

Author response: R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

10.7554/elife.43026.017 ◽

2019 ◽

Cited By ~ 1

Author(s):

Jeroen Overman ◽

Frank Fontaine ◽

Jill Wylie-Sears ◽

Mehdi Moustaqil ◽

Lan Huang ◽

...

Keyword(s):

Transcription Factor ◽

Small Molecule ◽

Author Response ◽

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers

EBioMedicine ◽

10.1016/j.ebiom.2016.04.032 ◽

2016 ◽

Vol 8 ◽

pp. 117-131 ◽

Cited By ~ 40

Author(s):

Anuradha Illendula ◽

Jane Gilmour ◽

Jolanta Grembecka ◽

Venkata Sesha Srimath Tirumala ◽

Adam Boulton ◽

...

Keyword(s):

Transcription Factor ◽

Small Molecule ◽

P08.21 Discovery of CT-179--a small molecule inhibitor of the transcription factor OLIG2 with potent anti-tumour activity in high-grade glioma

Neuro-Oncology ◽

10.1093/neuonc/nox036.211 ◽

2017 ◽

Vol 19 (suppl_3) ◽

pp. iii58-iii59

Author(s):

S. Chen ◽

S. A. Greenall ◽

G. Beaton ◽

G. Stein ◽

G. Alton ◽

...

Keyword(s):

Transcription Factor ◽

Small Molecule ◽

High Grade Glioma ◽

High Grade ◽

Anti Tumour Activity ◽

Molecule Inhibitor ◽

Tumour Activity

Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ

Scientific Reports ◽

10.1038/s41598-019-46948-5 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 8

Author(s):

Cecilia Hurtado ◽

Alena Safarova ◽

Michael Smith ◽

Raeeun Chung ◽

Arne A. N. Bruyneel ◽

...

Keyword(s):

Transcription Factor ◽

Notch Signaling ◽

Small Molecule ◽

EXTH-08. DISCOVERY OF CT-179: A SMALL MOLECULE INHIBITOR OF THE OLIG2 TRANSCRIPTION FACTOR WITH POTENT ANTI-TUMOUR ACTIVITY IN HIGH-GRADE GLIOMA

Neuro-Oncology ◽

10.1093/neuonc/nox168.304 ◽

2017 ◽

Vol 19 (suppl_6) ◽

pp. vi74-vi74

Author(s):

Terrance Johns

Keyword(s):

Transcription Factor ◽

Small Molecule ◽

High Grade Glioma ◽

High Grade ◽

Anti Tumour Activity ◽

Molecule Inhibitor ◽

Tumour Activity

A small-molecule inhibitor of the aberrant transcription factor CBF -SMMHC delays leukemia in mice

Science ◽

10.1126/science.aaa0314 ◽

2015 ◽

Vol 347 (6223) ◽

pp. 779-784 ◽

Cited By ~ 67

Author(s):

A. Illendula ◽

J. A. Pulikkan ◽

H. Zong ◽

J. Grembecka ◽

L. Xue ◽

...

Keyword(s):

Transcription Factor ◽

Small Molecule ◽

Decision letter: R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

10.7554/elife.43026.016 ◽

2018 ◽

Author(s):

Gou Young Koh ◽

Pia Ostergaard

Keyword(s):

Transcription Factor ◽

Small Molecule ◽

Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1121606109 ◽

2012 ◽

Vol 109 (24) ◽

pp. 9623-9628 ◽

Cited By ~ 217

Author(s):

X. Zhang ◽

P. Yue ◽

B. D. G. Page ◽

T. Li ◽

W. Zhao ◽

...

Keyword(s):

Lung Cancer ◽

Transcription Factor ◽

Small Molecule ◽

Human Breast ◽

Molecule Inhibitor ◽

Orally Bioavailable