Amino Acid Composition and NH2-Terminal Amino Acid Sequence of Rat Platelet Secretory Phospholipase A21

1987 ◽  
Vol 101 (5) ◽  
pp. 1311-1314 ◽  
Author(s):  
Makio HAYAKAWA ◽  
Kazuhiko HORIGOME ◽  
Ichiro KUDO ◽  
Motowo TOMITA ◽  
Shoshichi NOJIMA ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Terminal Amino Acid ◽  
Secretory Phospholipase ◽  
Terminal Amino ◽  
Terminal Amino Acid Sequence

The Amino Acid Sequence of Glucagon. I. Amino Acid Composition and Terminal Amino Acid Analyses

1957 ◽  
Vol 79 (11) ◽  
pp. 2794-2798 ◽  
Author(s):  
W. W. Bromer ◽  
A. Staub ◽  
E. R. Diller ◽  
H. L. Bird ◽  
L. G. Sinn ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Terminal Amino Acid ◽  
Terminal Amino

C-Terminal amino acid sequence of chicken pepsinogen and its homology with sequences of other acid proteases

1980 ◽  
Vol 45 (4) ◽  
pp. 1144-1154 ◽  
Author(s):  
Miroslav Baudyš ◽  
Helena Keilová ◽  
Vladimír Kostka
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
The Other ◽  
Terminal Sequence ◽  
Terminal Part ◽  
Terminal Amino Acid ◽  
Tryptic Peptides ◽  
Terminal Amino ◽  
High Degree ◽  
Terminal Amino Acid Sequence

To determine the primary structure of the C-terminal part of the molecule of chicken pepsinogen the tryptic, chymotryptic and thermolytic digest of the protein were investigated and peptides derived from this region were sought. These peptides permitted the following 21-residue C-terminal sequence to be determined: ...Ile-Arg-Glu-Tyr-Tyr-Val-Ile-Phe-Asp-Arg-Ala-Asn-Asn-Lys-Val-Gly-Leu-Ser-Pro-Leu-Ser.COOH. A comparison of this structure with the C-terminal sequential regions of the other acid proteases shows a high degree of homology between chicken pepsinogen and these proteases (e.g., the degree of homology with respect to hog pepsinogen and calf prochymosin is about 66%). Additional tryptic peptides, derived from the N-terminal part of the zymogen molecule whose amino acid sequence has been reported before, were also obtained in this study. This sequence was extended by two residues using an overlapping peptide. An ancillary result of this study was the isolation of tryptic peptides derived from other regions of the zymogen molecule.

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