scholarly journals A Comparison of Pressure Pain Detection Thresholds in People With Chronic Low Back Pain and Volunteers Without Pain

2005 ◽  
Vol 85 (10) ◽  
pp. 1085-1092 ◽  
Author(s):  
R Jason S Giesbrecht ◽  
Michele C Battié
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Spine ◽  
Chronic Low Back Pain ◽  
Primary Care Physicians ◽  
Detection Threshold ◽  
Test Site ◽  
Low Back ◽  
Pressure Pain ◽  
Pain Detection

Abstract Background and Purpose. Palpation is often utilized in the physical examination of patients with low back pain. The purpose of this study was to compare the pressure pain detection threshold (PPDT) of people with chronic low back pain (CLBP) and subjects without pain. Subjects and Methods. Thirty female subjects with CLBP were recruited from the offices of primary care physicians and physical therapists and compared with 30 female volunteers without pain for differences in PPDT at 6 sites tested bilaterally. Results. A significantly lower mean PPDT was found for all test site groups in subjects with CLBP compared with subjects without pain. A lower global PPDT was found in subjects with CLBP compared with subjects without pain (5.6 lb/cm2 versus 6.9 lb/cm2). This also was the case for PPDT for the group of test sites unrelated to the lumbar spine (5.1 lb/cm2 versus 6.1 lb/cm2) and for PPDT related to the lumbar spine (5.9 lb/cm2 versus 8.0 lb/cm2). Discussion and Conclusion. Neurobiological or biopsychosocial influences may have contributed to the lower PPDT evident in subjects with CLBP. Subjects with CLBP demonstrated a lower global PPDT compared with subjects without pain, which should be taken into account when interpreting findings of pain or tenderness from palpation.

scholarly journals Quantitative sensory tests fairly reflect immediate effects of oxycodone in chronic low-back pain

2017 ◽  
Vol 17 (1) ◽  
pp. 107-115 ◽  
Author(s):  
Jürg Schliessbach ◽  
Andreas Siegenthaler ◽  
Lukas Bütikofer ◽  
Pascal Vuilleumier ◽  
Peter Jüni ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Pain Threshold ◽  
Detection Threshold ◽  
Single Stimulus ◽  
Low Back ◽  
Pain Detection ◽  
Quantitative Sensory Tests ◽  
Sensory Tests

AbstractIntroductionQuantitative sensory tests (QST) can be used for profiling anti-nociceptive effects of analgesics. However, anti-nociceptive effects detected by QST are not necessarily associated with analgesic effects in pain patients. As part of a large investigation on low back pain, this paper describes the immediate analgesic and anti-nociceptive effects of oxycodone in chronic low-back pain and ranks different QST according to their ability to reflect this effect. The results are expected to support the selection of QST for future studies on potential novel opioid agonists in human pain.MethodsIn this randomized, placebo-controlled and double-blinded cross-over study, 50 patients with chronic low-back pain received a single oral dose of oxycodone 15 mg or active placebo, and underwent multiple QST testing. The intensity of low-back pain was recorded during 2 h. The areas under the ROC curves and 95% confidence intervals were determined, whereby responder status (≤30% pain reduction) was set as reference variable and changes in QST from baseline were set as classifiers.ResultsSignificant analgesic effect on low-back pain as well as anti-nociceptive effects for almost all QST parameters were observed. The QST with the highest area under the curve were heat pain detection threshold (0.65,95%-CI 0.46 to 0.83), single-stimulus electrical pain threshold (0.64,95%-CI 0.47 to 0.80) and pressure pain detection threshold (0.63,95%-CI 0.48 to 0.79).ConclusionsThe results suggest that anti-nociceptive effects assessed by QST fairly reflect clinical efficacy of oxycodone on low-back pain. Pressure pain detection threshold, heat pain detection threshold and single-stimulus electrical pain threshold may be more suitable to sort out potential non-responders rather than identifying potential responders to opioid medication. Future pre-clinical human research may consider these results when investigating the analgesic effect of opioid agonists by means of QST.

Medical and non-medical direct costs of chronic low back pain in patients consulting primary care physicians in France

2010 ◽  
Vol 24 (1) ◽  
pp. 101-108 ◽  
Author(s):  
Fanny Depont ◽  
Elke Hunsche ◽  
Abdelilah Abouelfath ◽  
Thierno Diatta ◽  
Isabelle Addra ◽  
...  
Keyword(s):  
Primary Care ◽  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Primary Care Physicians ◽  
Direct Costs ◽  
Low Back

scholarly journals SPECT/CT imaging of the lumbar spine in chronic low back pain: a case report

2011 ◽  
Vol 19 (1) ◽  
Author(s):  
Michael H Carstensen ◽  
Mashael Al-Harbi ◽  
Jean-Luc Urbain ◽  
Tarik-Zine Belhocine
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Case Report ◽  
Lumbar Spine ◽  
Chronic Low Back Pain ◽  
Ct Imaging ◽  
Low Back

Clinical Review of Lumbar Spine Fusion for Chronic Low Back Pain Due to Degenerative Disc Disease

2012 ◽  
Vol 12 (9) ◽  
pp. S147-S148 ◽  
Author(s):  
Frank M. Phillips ◽  
Paul J. Slosar ◽  
Jim A. Youssef ◽  
Gunnar B. Andersson ◽  
Frank J. Papatheofanis
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Spine ◽  
Clinical Review ◽  
Chronic Low Back Pain ◽  
Degenerative Disc Disease ◽  
Spine Fusion ◽  
Low Back ◽  
Disc Disease ◽  
Lumbar Spine Fusion

scholarly journals Primary Care Physicians’ Attitudes and Beliefs towards Chronic Low Back Pain: An Asian Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (1) ◽  
pp. e0117521 ◽  
Author(s):  
Regina W. S. Sit ◽  
Benjamin H. K. Yip ◽  
Dicken C. C. Chan ◽  
Samuel Y. S. Wong
Keyword(s):  
Primary Care ◽  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Primary Care Physicians ◽  
Attitudes And Beliefs ◽  
Low Back ◽  
Asian Study

scholarly journals Atraumatic Bilateral Lumbar Pedicle Fractures in a Patient with Back Pain and History of Long- Term Bisphosphonate Therapy: A Case Report

2020 ◽  
pp. 97-102
Author(s):  
Alec L. Meleger
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Case Report ◽  
Lumbar Spine ◽  
Conservative Management ◽  
Chronic Low Back Pain ◽  
Bisphosphonate Therapy ◽  
Low Back ◽  
History Of ◽  
Lumbar Pedicle

of atypical femoral fractures is a known complication of chronic bisphosphonate therapy; however, the finding of atraumatic lumbar pedicle fractures without a prior history of spinal surgery or contralateral spondylolysis is rare. While a few cases of osteoporotic pedicle fractures associated with adjacent vertebral compression fractures have been reported, only a single case of isolated atraumatic bilateral pedicle fractures has been published in a patient who had been on chronic risedronate therapy of 10-year duration. Case Report: The present case report illustrates a 63-year-old man who developed isolated atraumatic bilateral lumbar pedicle fractures after 3 years and 5 months on alendronate treatment. The patient’s past medical history had been significant for osteoporosis with a lumbar spine T-score of -2.7. At the time of initial diagnosis, a comprehensive work-up for secondary causes of osteoporosis proved to be negative; this was followed by initiation of bisphosphonate treatment with 70 mg of alendronate once per week. Ten months after starting bisphosphonate therapy, he underwent magnetic resonance imaging (MRI) of the lumbar spine for low back pain that had not responded to conservative management, with imaging not revealing any evidence of pedicle fractures or pedicle stress reaction. He was again seen in the spine clinic, for atraumatic exacerbation of his chronic low back pain with concurrent right lower extremity radiation, 6 months after stopping bisphosphonate therapy. Since the patient failed to respond to conservative management over the ensuing 6 months, a repeat MRI was obtained, which showed new acute/subacute bilateral L5 pedicle fractures. Conclusion: An isolated atraumatic lumbar pedicle fracture may be an additional type of atypical fracture associated with chronic bisphosphonate therapy in an osteoporotic patient. Key words: Chronic low back pain, bisphosphonate, alendronate, pedicle fracture Pain Medicine

scholarly journals Recognition of Chronic Low Back Pain During Lumbar Spine Movements Based on Surface Electromyography Signals

IEEE Access ◽  
2018 ◽  
Vol 6 ◽  
pp. 65027-65042 ◽  
Author(s):  
Wenjing Du ◽  
Olatunji Mumini Omisore ◽  
Huihui Li ◽  
Kamen Ivanov ◽  
Shipeng Han ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Spine ◽  
Chronic Low Back Pain ◽  
Surface Electromyography ◽  
Low Back ◽  
Electromyography Signals
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