Structure and mechanism of isopropylmalate dehydrogenase from Arabdiopsis thaliana : insights on leucine and aliphatic glucosinolate biosynthesis

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Soon Goo Lee
Keyword(s):  
Glucosinolate Biosynthesis ◽  
Isopropylmalate Dehydrogenase ◽  
Aliphatic Glucosinolate

scholarly journals Glucose signalling positively regulates aliphatic glucosinolate biosynthesis

2013 ◽  
Vol 64 (4) ◽  
pp. 1097-1109 ◽  
Author(s):  
Huiying Miao ◽  
Jia Wei ◽  
Yanting Zhao ◽  
Huizhuan Yan ◽  
Bo Sun ◽  
...  
Keyword(s):  
Glucosinolate Biosynthesis ◽  
Glucose Signalling ◽  
Aliphatic Glucosinolate

scholarly journals CRISPR-Cas9-mediated editing of myb28 impairs glucoraphanin accumulation of Brassica oleracea in the field

2020 ◽  
Author(s):  
Mikhaela Neequaye ◽  
Sophia Stavnstrup ◽  
Tom Lawrenson ◽  
Penny Hundleby ◽  
Perla Troncoso-Rey ◽  
...  
Keyword(s):  
Gene Editing ◽  
European Court Of Justice ◽  
Knockout Mutant ◽  
Glucosinolate Biosynthesis ◽  
Court Of Justice ◽  
European Court ◽  
Indole Glucosinolate ◽  
Cysteine Sulfoxide ◽  
Aliphatic Glucosinolate

SummaryWe sought to quantify the role of MYB28 in the regulation of aliphatic glucosinolate biosynthesis and associated sulphur metabolism in field-grown B. oleracea with the use of CRISPR-Cas9-mediated gene editing technology. We describe the first characterised myb28 knockout mutant in B. oleracea, and the first UK field trial of CRISPR-Cas9-mediated gene edited plants under the European Court of Justice interpretation of the 2001/18 EU GMO directive. We report that knocking-out myb28 results in downregulation of aliphatic glucosinolate biosynthesis genes and reduction in accumulation of the methionine-derived glucosinolate, glucoraphanin, in leaves and florets of field-grown myb28 mutant broccoli plants. There were no significant changes to the accumulation of sulphate, S-methyl cysteine sulfoxide and indole glucosinolate in leaf and floret tissues.

scholarly journals HAG2/MYB76 and HAG3/MYB29 exert a specific and coordinated control on the regulation of aliphatic glucosinolate biosynthesis inArabidopsis thaliana

2008 ◽  
Vol 177 (3) ◽  
pp. 627-642 ◽  
Author(s):  
Tamara Gigolashvili ◽  
Martin Engqvist ◽  
Ruslan Yatusevich ◽  
Caroline Müller ◽  
Ulf-Ingo Flügge
Keyword(s):  
Coordinated Control ◽  
Glucosinolate Biosynthesis ◽  
Aliphatic Glucosinolate

scholarly journals Three genes encoding AOP2, a protein involved in aliphatic glucosinolate biosynthesis, are differentially expressed inBrassica rapa

2015 ◽  
Vol 66 (20) ◽  
pp. 6205-6218 ◽  
Author(s):  
Jifang Zhang ◽  
Zhiyuan Liu ◽  
Jianli Liang ◽  
Jian Wu ◽  
Feng Cheng ◽  
...  
Keyword(s):  
Differentially Expressed ◽  
Glucosinolate Biosynthesis ◽  
Genes Encoding ◽  
Aliphatic Glucosinolate
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