Impact of Common Polymorphic Variant A503V in POR on Drug Metabolism: Implications for POR Deficiency

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Maria Natalia Rojas Velazquez ◽  
Shaheena Parween ◽  
Amit V. Pandey
Author(s):  
I. V. Kudaeva ◽  
O. A. Dyakovich ◽  
I. M. Eshchina

It was found that in persons exposed by vinyl chloride, the risk of hypertension increases six times in carriers of the genotype C/C polymorphic variant of Leu28Pro gene APO E, 9.5 times - in carriers of the genotype T/T polymorphic variant C786T gene eNOS3 and 1.75 times - in carriers of the genotype T/C polymorphic variant Met 235 Thr gene AGT.


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