scholarly journals V. Amygdalina Extracts Inhibit the Growth of Estrogen Receptor Positive/Negative Human Breast Carcinoma Cells In Vitro

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Brittany Robinson ◽  
Lecia Gesham ◽  
Ernest Izevbigie ◽  
Joseph A Cameron
Keyword(s):  
Estrogen Receptor ◽  
Breast Carcinoma ◽  
Carcinoma Cells ◽  
Human Breast Carcinoma ◽  
Human Breast ◽  
Breast Carcinoma Cells ◽  
Estrogen Receptor Positive ◽  
Human Breast Carcinoma Cells

Anti-invasive effect of gambogic acid in MDA-MB-231 human breast carcinoma cells

2008 ◽  
Vol 86 (5) ◽  
pp. 386-395 ◽  
Author(s):  
Qi Qi ◽  
Na Lu ◽  
Xiao-tang Wang ◽  
Hong-yan Gu ◽  
Yong Yang ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Carcinoma Cells ◽  
Human Breast Carcinoma ◽  
Matrix Metalloproteinase 2 ◽  
Migration And Invasion ◽  
Gambogic Acid ◽  
Human Breast ◽  
Breast Carcinoma Cells ◽  
Human Breast Carcinoma Cells

Gambogic acid (GA) has been known to have antitumor activity in vitro and in vivo. In the present study, we investigated the anti-invasive effects of GA in MDA-MB-231 human breast carcinoma cells. The results indicated that GA significantly inhibited the adhesion, migration, and invasion of the cells in vitro tested by the heterotypic adhesion assay, wound migration assay, and chamber invasion assay. Results of Western blotting and immunocytochemistry analysis showed that GA could suppress the expressions of matrix metalloproteinase 2 (MMP-2) and 9 (MMP-9) in MDA-MB-231 cells. Furthermore, gelatin zymography revealed that GA decreased the activities of MMP-2 and MMP-9. Additionally, GA exerted an inhibitory effect on the phosphorylation of ERK1/2 and JNK, while it had no effect on p38. Taken together, our results demonstrated the anti-invasive property of GA for the first time and indicated it could serve as a promising drug for the treatment of cancer metastasis.

Neospora caninum: In vitro culture of tachyzoites in MCF-7 human breast carcinoma cells

2010 ◽  
Vol 126 (4) ◽  
pp. 536-539 ◽  
Author(s):  
Qiang Lv ◽  
Jianhua Li ◽  
Pengtao Gong ◽  
Shenyang Xing ◽  
Xichen Zhang
Keyword(s):  
Breast Carcinoma ◽  
In Vitro Culture ◽  
Neospora Caninum ◽  
Carcinoma Cells ◽  
Human Breast Carcinoma ◽  
Human Breast ◽  
Breast Carcinoma Cells ◽  
Human Breast Carcinoma Cells ◽  
Mcf 7

scholarly journals Inhibition of cyclin D expression in human breast carcinoma cells by retinoids in vitro

Oncogene ◽  
1997 ◽  
Vol 15 (1) ◽  
pp. 107-115 ◽  
Author(s):  
Qun Zhou ◽  
Maryalice Stetler-Stevenson ◽  
Patricia S Steeg
Keyword(s):  
Breast Carcinoma ◽  
Carcinoma Cells ◽  
Human Breast Carcinoma ◽  
Cyclin D ◽  
Human Breast ◽  
Breast Carcinoma Cells ◽  
Human Breast Carcinoma Cells
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