Lumbo-Sacral Chordoma with High-Grade Malignant Cartilaginous and Spindle Cell Components

1990 ◽  
Vol 14 (4) ◽  
pp. 384-389 ◽  
Author(s):  
Ralph H. Hruban ◽  
Michael May ◽  
Ralph C. Marcove ◽  
Andrew G. Huvos
Keyword(s):  
Spindle Cell ◽  
High Grade ◽  
Sacral Chordoma ◽  
Cell Components

Malignant Transformation of Metaplastic Thymoma into High-Grade Sarcomatoid Carcinoma: A Case Report

2021 ◽  
pp. 106689692110704
Author(s):  
Zheng Hua Piao ◽  
Jin Ping Chen ◽  
Hai Ren Chen ◽  
Xin Cheng Zhou
Keyword(s):  
Mediastinal Mass ◽  
Spindle Cell ◽  
Postoperative Radiotherapy ◽  
Sarcomatoid Carcinoma ◽  
Anterior Mediastinal Mass ◽  
High Grade ◽  
Ki 67 ◽  
Cellular Atypia ◽  
Spindle Cells ◽  
Cell Components

The correlation of histogenesis between metaplastic thymoma and thymic sarcomatoid carcinoma is unclear. We report a case of metaplastic thymoma transformed into high-grade sarcomatoid carcinoma. A 64  ×  54  ×  32 mm anterior mediastinal mass in a 61-year-old woman microscopically consisted mainly of classic metaplastic thymoma, with the center dominated by high-grade sarcomatoid carcinoma. In some areas, both epithelial and spindle cell components of the metaplastic thymoma showed increased cellular atypia, mitotic activity, and focal necrosis and gradually transformed into the polygonal/pleomorphic and spindle cell components of sarcomatoid carcinoma. Immunohistochemically, the characteristics of the polygonal/pleomorphic sarcomatoid cells were similar to those of the epithelial component of metaplastic thymoma, while the spindle sarcomatoid cells were more similar to the spindle cells component of metaplastic thymoma. The Ki-67 index was less than 5% in the metaplastic thymoma areas but up to 70% in the sarcomatoid carcinoma area. Radical operation and postoperative radiotherapy were performed. Multifocal relapses at the pleura occurred 13 months after surgery.

Encapsulated Follicular Thyroid Carcinoma Exhibiting Glandular and Spindle Cell Components

1996 ◽  
Vol 192 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Y. Mizukami ◽  
A. Nonomura ◽  
T. Michigishi ◽  
M. Noguchi ◽  
T. Ishizaki
Keyword(s):  
Thyroid Carcinoma ◽  
Spindle Cell ◽  
Follicular Thyroid Carcinoma ◽  
Cell Components

Aggressive high-grade mucinous tubular and spindle cell carcinoma

2009 ◽  
Vol 40 (6) ◽  
pp. 906-907 ◽  
Author(s):  
Stela Bulimbasic ◽  
Danica Ljubanovic ◽  
Radek Sima ◽  
Michal Michal ◽  
Ondrej Hes ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
High Grade

INTRAARTERIAL CISPLATIN AND CAFFEINE WITH/WITHOUT DOXORUBICIN FOR MUSCULOSKELETAL HIGH-GRADE SPINDLE-CELL SARCOMA

1994 ◽  
Author(s):  
H TSUCHIYA ◽  
K TOMITA ◽  
H YASUTAKE ◽  
Y TAKAGI ◽  
S KATSUO ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Spindle Cell Sarcoma ◽  
High Grade ◽  
Cell Sarcoma

scholarly journals A case of high-grade mucinous tubular and spindle cell carcinoma

2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Koujin Miura ◽  
Yasushi Adachi ◽  
Toshiaki Shirahase ◽  
Yoji Nagashima ◽  
Kazuki Suemune ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Poor Prognosis ◽  
Spindle Cell ◽  
Left Kidney ◽  
Spindle Cell Carcinoma ◽  
Low Grade ◽  
High Grade ◽  
Tomography Scan

Abstract Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare renal cell carcinoma that initially presents as low-grade renal cell carcinoma. However, cases of MTSCC with high-grade histology and poor prognosis have been reported. Here, we report a case of MTSCC with high-grade histological features and metastasis. A 77-year-old woman consulted a hospital following frequent and painful micturition. Computed tomography scan revealed a tumor of the left kidney. First, chemotherapy was performed, with no effects. Therefore, nephrectomy was subsequently performed. Histologically, the tumor showed the features of MTSCC with sarcomatoid component. Metastasis of the tumor into the lymph node was also observed. Although adjuvant chemotherapy was performed after nephrectomy, metastasis to the lungs and bone and local recurrence was observed. The patient is still alive 2 years after nephrectomy with metastasis and recurrence of the tumor. High-grade MTSCC shows a relatively poor prognosis, specifically MTSCC with metastasis upon nephrectomy.

Primary hepatic lymphoma with spindle cell components: a case report

2006 ◽  
Vol 449 (5) ◽  
pp. 591-596 ◽  
Author(s):  
Hiroko Hayashi ◽  
Hiroshi Ohtani ◽  
Takashi Ueda ◽  
Junzo Yamaguchi ◽  
Kunihide Izawa ◽  
...  
Keyword(s):  
Case Report ◽  
Spindle Cell ◽  
Primary Hepatic Lymphoma ◽  
Cell Components

Adenoid cystic carcinoma with high-grade transformation forming spindle cell component of the submandibular gland

2019 ◽  
Vol 46 (6) ◽  
pp. 934-939 ◽  
Author(s):  
Masaru Miyazaki ◽  
Mikiko Aoki ◽  
Kaori Koga ◽  
Makoto Hamasaki ◽  
Yoshikazu Sugiyama ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Submandibular Gland ◽  
Spindle Cell ◽  
High Grade ◽  
Cell Component ◽  
Spindle Cell Component ◽  
Adenoid Cystic ◽  
High Grade Transformation
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