Nitric oxide synthase in trigeminal ganglion cells projecting to the cochlea of rat and guinea pig

Neuroreport ◽  
1999 ◽  
Vol 10 (12) ◽  
pp. 2641-2645 ◽  
Author(s):  
Randolf Riemann ◽  
Stefan Reuss
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Guinea Pig ◽  
Trigeminal Ganglion ◽  
Ganglion Cells ◽  
Oxide Synthase

scholarly journals Modulation of guinea-pig cardiac L-type calcium current by nitric oxide synthase inhibitors

1998 ◽  
Vol 506 (3) ◽  
pp. 639-651 ◽  
Author(s):  
Maria Pia Gallo ◽  
Dario Ghigo ◽  
Amalia Bosia ◽  
Giuseppe Alloatti ◽  
Costanzo Costamagna ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Guinea Pig ◽  
Calcium Current ◽  
Nitric Oxide Synthase Inhibitors ◽  
Oxide Synthase

scholarly journals Specificity of Antibodies to Nitric Oxide Synthase Isoforms in Human, Guinea Pig, Rat, and Mouse Tissues

1998 ◽  
Vol 46 (12) ◽  
pp. 1385-1391 ◽  
Author(s):  
Wilko Coers ◽  
Wim Timens ◽  
Claudia Kempinga ◽  
Pieter A. Klok ◽  
Han Moshage
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Guinea Pig ◽  
Mouse Tissues ◽  
Oxide Synthase

Guinea pig pancreatic neurons: morphology, neurochemistry, electrical properties, and response to 5-HT

1997 ◽  
Vol 273 (6) ◽  
pp. G1273-G1289 ◽  
Author(s):  
Min-Tsai Liu ◽  
Annette L. Kirchgessner
Keyword(s):  
Nitric Oxide ◽  
Electrical Properties ◽  
Nitric Oxide Synthase ◽  
Guinea Pig ◽  
Choline Acetyltransferase ◽  
Synaptic Input ◽  
Action Potentials ◽  
Receptor Desensitization ◽  
5 Ht Uptake ◽  
Oxide Synthase

The morphology, neurochemistry, and electrical properties of guinea pig pancreatic neurons were determined. The majority of neurons expressed choline acetyltransferase (ChAT) immunoreactivity; however, ChAT-negative neurons were also found. Both cholinergic and noncholinergic neurons expressed nitric oxide synthase (NOS) immunoreactivity. Three types of pancreatic neurons were distinguished. Phasic neurons fired action potentials (APs) at the onset of depolarizing current pulse, tonic neurons spiked throughout the duration of a suprathreshold depolarizing pulse, and APs could not be generated in nonspiking neurons, even though they did receive synaptic input. APs were tetrodotoxin sensitive, and all types of neurons received fast and slow excitatory postsynaptic potentials (EPSPs). Fast EPSPs had cholinergic and noncholinergic components. The majority of pancreatic neurons appeared to innervate the acini. NOS- and/or neuropeptide Y-immunoreactive phasic and tonic neurons were found. Microejection of 5-hydroxytryptamine (5-HT) caused a slow depolarization that was inhibited by the 5-HT1P antagonist N-acetyl-5-hydroxytryptophyl-5-hydroxytryptophan amide and mimicked by the 5-HT1Pagonist 6-hydroxyindalpine. A pancreatic 5-HT transporter was located, and inhibition of 5-HT uptake by fluoxetine blocked slow EPSPs in 5-HT-responsive neurons by receptor desensitization.

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