Proviral HIV-1 DNA in subjects followed since primary HIV-1 infection who suppress plasma viral load after one year of highly active antiretroviral therapy

AIDS ◽  
2001 ◽  
Vol 15 (6) ◽  
pp. 665-673 ◽  
Author(s):  
Nicole Ngo-Giang-Huong ◽  
Christiane Deveau ◽  
Isabelle Da Silva ◽  
Isabelle Pellegrin ◽  
Alain Venet ◽  
...  
2001 ◽  
Vol 174 (4) ◽  
pp. 199-200 ◽  
Author(s):  
Choo B Chew ◽  
Marcel J Lerol ◽  
Cassy Workman ◽  
Dominic E Dwyer

2003 ◽  
Vol 77 (3) ◽  
pp. 2271-2275 ◽  
Author(s):  
Michele Di Mascio ◽  
Geethanjali Dornadula ◽  
Hui Zhang ◽  
Julie Sullivan ◽  
Yan Xu ◽  
...  

ABSTRACT Three of five virally suppressed human immunodeficiency virus type I (HIV-1)-infected patients treated with highly active antiretroviral therapy and followed intensively with a supersensitive reverse transcriptase PCR assay with a lower limit of quantitation of 5 copies/ml showed statistically significant viral load decays below 50 copies/ml, with half-lives of 5 to 8 months and a mean of 6 months. This range of half-lives is consistent with the estimated half-life of the latent HIV-1 reservoir in the peripheral blood. Those patients without decay of viral load in plasma may have significant cryptic HIV-1 residual replication.


2008 ◽  
Vol 19 (5) ◽  
pp. 357-358
Author(s):  
Pierre Tattevin ◽  
Anne Maillard ◽  
Olivier Tribut ◽  
Emilie Saíkali ◽  
Cedric Arvieux ◽  
...  

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