The Role of Hepatobiliary Scintigraphy in the Follow-up of Benign Liver Tumors Secondary to Oral Contraceptive Use

2001 ◽  
Vol 26 (11) ◽  
pp. 946-947
Author(s):  
SERGEY BYKOV ◽  
IZAK GARTY ◽  
LEONID CHEREVINSKY ◽  
ORI SEGOL ◽  
DIMITRY LUMELSKY
Keyword(s):  
Oral Contraceptive ◽  
Contraceptive Use ◽  
Liver Tumors ◽  
Hepatobiliary Scintigraphy ◽  
Benign Liver Tumors ◽  
Oral Contraceptive Use ◽  
Benign Liver

Benign Liver Tumors and Oral Contraceptive Therapy

1979 ◽  
Vol 13 (11) ◽  
pp. 680-689 ◽  
Author(s):  
Betty L. Warren ◽  
Gail D. Bellward
Keyword(s):  
Oral Contraceptive ◽  
Liver Tumors ◽  
Tumor Formation ◽  
Benign Liver Tumors ◽  
Contraceptive Steroid ◽  
Contraceptive Steroids ◽  
Contraceptive Therapy ◽  
Altered Cell ◽  
Benign Liver

Clinical data obtained from 1972–1978 on 107 cases of oral-contraceptive-steroid-associated hepatic adenomas is presented in tabular form. Although a cause-and-effect relationship has not been definitively established, experimental evidence that supports an etiological role of contraceptive steroids in the production of benign liver tumors is described. Based on metabolic and toxicity studies, a mechanism is postulated whereby contraceptive steroid therapy may result in induced activities of drug metabolizing enzymes. In certain circumstances, increased levels of activated metabolites may irreversibly bind to hepatic macromolecules and produce altered cell growth. The possible promoter role of oral contraceptive steroids in tumor formation is discussed.

Oral Contraceptive Associated Liver Tumors

1978 ◽  
Vol 12 (9) ◽  
pp. 523-527 ◽  
Author(s):  
James A. Waschek ◽  
Dennis K. Helling
Keyword(s):  
Oral Contraceptive ◽  
Large Scale ◽  
Contraceptive Use ◽  
Liver Tumors ◽  
Significant Risk ◽  
Clinical Aspects ◽  
Oral Contraceptive Use ◽  
Malignant Liver Tumors ◽  
Malignant Liver ◽  
Benign Liver

Over the past few years an association between oral contraceptive use and liver tumors has been suggested, and this is now being studied on an epidemiological basis. Large scale retrospective studies to date support a relationship between oral contraceptive use and benign liver tumors. These tumors carry a significant risk of spontaneous rupture. The possible relationship with malignant liver tumors is also discussed. Clinical aspects of these tumors are presented, as well as suspected oncogenic mechanisms.

Survey of primary liver tumors and oral contraceptive use

1979 ◽  
Vol 5 (2-3) ◽  
pp. 255-273 ◽  
Author(s):  
Josef Vana ◽  
Gerald P. Murphy ◽  
Billie L. Aronoff ◽  
Harvey W. Baker
Keyword(s):  
Oral Contraceptive ◽  
Contraceptive Use ◽  
Liver Tumors ◽  
Primary Liver Tumors ◽  
Oral Contraceptive Use
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