NON-INVASIVE MONITORING OF ARTERIAL BLOOD OXYGENATION IN ACUTELY ILL ADULT PATIENTS

1979 ◽  
Vol 7 (3) ◽  
pp. 136
Author(s):  
Hugo D. Montenegro ◽  
Mary Ellen Kelinhenz
2001 ◽  
Vol 18 (Supplement 21) ◽  
pp. 31-32
Author(s):  
I. Störmer ◽  
F. Baisch ◽  
J.-L. Romé ◽  
C. Hesse ◽  
W. Schlack

2017 ◽  
Vol 71 (2) ◽  
pp. 113-118
Author(s):  
Vesna Durnev ◽  
Venko Filipce ◽  
Aleksandra Gavrilovska Brzanov ◽  
Maja Mojsova Mijovska ◽  
Marina Temelkovska Stevanovska

Abstract Introduction. Cerebral oxymetry obtained with Near Infrared Spectroscopy (NIRS) provides noninvasive monitoring of microvasculature in the brain allowing for early recognition and preventive treatment of impaired cerebral oxygenation in traumatic brain injuries. Optimizing cerebral oxygenation is advocated to improve outcome in traumatic brain injured (TBI) hence the goal of this study was to determine the benefit of non invasive monitoring of cerebral oxygenation. Methods. Noninvasive monitoring was conducted in fifteen patients with traumatic brain injury. The values and changes in cerebral oxymetry were analyzed and compared with others tracked parameters: Glasgow Coma Scale on admission to determine the severity of traumatic brain injuries, systolic arterial blood pressure, mean arterial blood pressure, pulse oxymetry, and regular laboratory test. Regional cerebral oxygenation was measured using cerebral oxymetar INVOS 5100 Somanetics®. Results. According to obtained data, we noticed that any change in hemodynamic profile directly influenced the regional cerebral oxygen saturation. Higher changes in values of 15 % and more from basal ones correlate with unfavorable outcome as neurologic sequels. Decreased values of rSO2 in our study were rectified with several simple interventions. In our cases parameter which was most prominent cause for disturbed rSO2 was decreased mean arterial blood pressure. Conclusion. Stable hemodynamic profile leads to optimized cerebral oxygenation. Monitoring the regional oxygen saturation influenced by several factors is important step for forehanded detection of adverse secondary brain injuries. NIRS technology as monitoring system has potential to have diagnostic value and enable right therapeutic decisions and consequently better prognosis in TBI. Continued study of the benefits of cerebral oxygen monitoring is warranted.


2020 ◽  
Author(s):  
J. Poublanc ◽  
O. Sobczyk ◽  
R. Shafi ◽  
J. Duffin ◽  
K. Uludag ◽  
...  

AbstractBackgroundThe paramagnetic properties of deoxyhemoglobin shorten T2* as do gadolinium based contrast agents. Induction of abrupt changes in arterial deoxyhemoglobin concentration ([dOHb]) can simulate intra-vascular injections of gadolinium for perfusion imaging.AimTo demonstrate the feasibility of making rapid changes in pulmonary venous hemoglobin saturation and employing the resulting changes in T2* to calculate flow metrics in the brain.MethodsA gas blender with a sequential gas delivery breathing circuit and software enabling prospective arterial blood gas targeting was used to implement rapid isocapnic lung changes in the partial pressure of blood oxygen (PaO2). Lung PO2 was initially lowered to induce a low baseline [dOHb]. PaO2 was then rapidly raised to PaO2 ∼ 100 mmHg for 10 seconds and then rapidly returned to baseline. Blood oxygenation level dependent (BOLD) MRI signal changes were measured over time.ResultsArrival delay, signal amplitude and change in BOLD discriminated between large arteries, tissue and veins. The median half-time of BOLD signal in the middle cerebral artery was 1.7 s, indicating minimal dispersion confirming effective rapid modulation of pulmonary venous PO2. The contrast-to-noise ratio in the cortex was 3. Calculations of arrival delay, cerebral blood volume, mean transit time and cerebral blood flow were within normal ranges from published literature values.ConclusionNon-invasive induction of abrupt changes in [OHb] may function as a novel non-invasive vascular contrast agent for use in perfusion imaging.


1972 ◽  
Vol 16 (4) ◽  
pp. 375
Author(s):  
HANS J. BRONER ◽  
HENRI G. DOLL ◽  
PIERRE BERRYER ◽  
GABRIEL G. NAHAS

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