Nitric oxide synthase inhibition versus norepinephrine for the treatment of hyperdynamic sepsis in sheep

1996 ◽  
Vol 24 (5) ◽  
pp. 835-844 ◽  
Author(s):  
Michael Booke ◽  
Frank Hinder ◽  
Roy McGuire ◽  
Lillian D. Traber ◽  
Daniel L. Traber
1996 ◽  
Vol 83 (5) ◽  
pp. 1009-1013 ◽  
Author(s):  
Jorg Meyer ◽  
Michael Booke ◽  
Rene Waurick ◽  
Thomas Prien ◽  
Hugo Van Aken

1996 ◽  
Vol 83 (5) ◽  
pp. 1009-1013 ◽  
Author(s):  
Jorg Meyer ◽  
Michael Booke ◽  
Rene Waurick ◽  
Thomas Prien ◽  
Hugo Van Aken

Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).


2001 ◽  
Vol 120 (5) ◽  
pp. A684-A684
Author(s):  
I DANIELS ◽  
I MURRAY ◽  
W GODDARD ◽  
R LONG

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