The Cytochrome P450 Suicide Inhibitor, 1-aminobenzotriazole (ABT), Sensitizes Rats to Zymosan-Induced Multiple Organ Failure

1998 ◽  
Vol 26 (Supplement) ◽  
pp. 79A
Author(s):  
Joseph Carcillo ◽  
Curt Kost ◽  
Ken Korzekwa ◽  
Garth Jones ◽  
Robert Parise ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Multiple Organ Failure ◽  
Organ Failure ◽  
Multiple Organ

scholarly journals Cytochrome P450 Function in Pediatric Sepsis-Induced Multiple Organ Failure.♦ 179

1997 ◽  
Vol 41 ◽  
pp. 32-32 ◽  
Author(s):  
Lesley Doughty ◽  
Sandra Kaplan ◽  
Gilbert Burckhart ◽  
Reginald Frye ◽  
Joseph Carcillo
Keyword(s):  
Cytochrome P450 ◽  
Multiple Organ Failure ◽  
Organ Failure ◽  
Multiple Organ ◽  
Pediatric Sepsis

Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure

2003 ◽  
Vol 29 (6) ◽  
pp. 980-984 ◽  
Author(s):  
Joseph A. Carcillo ◽  
Lesley Doughty ◽  
Danny Kofos ◽  
Reginald F. Frye ◽  
Sandra S. Kaplan ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Multiple Organ Failure ◽  
Organ Failure ◽  
Multiple Organ

Clinical case of periostitis in pregnant women complicated by sepsis

2020 ◽  
pp. 61-63
Author(s):  
S. Sh. Kakvaeva ◽  
M. A. Magomedova ◽  
A. N. Dzhalilova
Keyword(s):  
Pregnant Woman ◽  
Multiple Organ Failure ◽  
Pregnant Women ◽  
Organ Failure ◽  
Clinical Case ◽  
Clinical Observation ◽  
Infectious Agent ◽  
Modern Medicine ◽  
Multiple Organ ◽  
Number Of Patients

One of the most serious problems of modern medicine is sepsis. The number of patients undergoing this complication is 20–30 million (WHO) annually and has no tendency to decrease. Sepsis is characterized by severe multiple organ failure due to a violation of the response of the macroorganism to an infectious agent. Moreover, it is dangerous with high mortality. Sepsis often develops in patients with immunodeficiency conditions, which primarily include pregnant women. The article presents a clinical observation of a case of periostitis in a pregnant woman complicated by a septic state.

scholarly journals High-dose diquat poisoning: a case report

2021 ◽  
Vol 49 (6) ◽  
pp. 030006052110261
Author(s):  
Yanxia Huang ◽  
Renjing Zhang ◽  
Mei Meng ◽  
Dechang Chen ◽  
Yunxin Deng
Keyword(s):  
Renal Failure ◽  
Multiple Organ Failure ◽  
Organ Failure ◽  
Multiple Organ ◽  
High Dose ◽  
Severe Respiratory Failure ◽  
Aggressive Treatment ◽  
Lung Lesions ◽  
Pulmonary Lesions ◽  
New Treatment

Diquat is a widely used herbicide that is substituted for paraquat. With paraquat off the market, cases of diquat poisoning have been gradually increasing. The kidney is the most frequently impaired organ in diquat poisoning. Few cases of multiple organ failure caused by diquat have been reported. We herein describe a 30-year-old man who orally ingested about 160 mL of enriched diquat. Despite aggressive treatment, the patient’s condition progressed to multiple organ failure and death. The pulmonary lesions in this patient were different from those previously reported. This patient did not die of renal failure but of severe respiratory failure. He exhibited three different stages of pulmonary disease. The lung lesions in this case were unique. We hope that doctors will pay more attention to the lung lesions in patients with diquat poisoning in future and find new treatment methods to save the lives of such patients.

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