Collagenase Ointment and Polymyxin B Sulfate/Bacitracin Spray Versus Silver Sulfadiazine Cream in Partial-Thickness Burns: A Pilot Study

1994 ◽  
Vol 15 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Harry S. Soroff ◽  
Dawn H. Sasvary
Keyword(s):  
Pilot Study ◽  
Polymyxin B ◽  
Silver Sulfadiazine ◽  
Partial Thickness ◽  
Partial Thickness Burns

Pediatric Burn Treatment Using Tilapia Skin as a Xenograft for Superficial Partial-Thickness Wounds: A Pilot Study

2019 ◽  
Author(s):  
Edmar Maciel Lima Júnior ◽  
Manoel Odorico de Moraes Filho ◽  
Antonio Jorge Forte ◽  
Bruno Almeida Costa ◽  
Francisco Vagnaldo Fechine ◽  
...  
Keyword(s):  
Pilot Study ◽  
Test Group ◽  
Silver Sulfadiazine ◽  
Control Group ◽  
Burn Wound ◽  
Open Label ◽  
Burn Treatment ◽  
Partial Thickness ◽  
Partial Thickness Burn ◽  
Partial Thickness Burns

Abstract This study aims to evaluate the efficacy of Nile tilapia skin as a xenograft for the treatment of partial-thickness burn wounds in children. This is an open-label, monocentric, randomized phase II pilot study conducted in Fortaleza, Brazil. The study population consisted of 30 children between the ages of 2 and 12 years with superficial “partial-thickness” burns admitted less than 72 hours from the thermal injury. In the test group, the tilapia skin was applied. In the control group, a thin layer of silver sulfadiazine cream 1% was applied. Tilapia skin showed good adherence to the wound bed, reducing the number of dressing changes required, the amount of anesthetics used, and providing benefits for the patients and also for healthcare professionals, by reducing the overall work load. The number of days to complete burn wound healing, the total amount of analgesics required throughout the treatment, burn improvement on the day of dressing removal, and pain throughout the treatment were similar to the conventional treatment with silver sulfadiazine. Thus, tilapia skin can be considered an effective and low-cost extra resource in the therapeutic arsenal of pediatric superficial partial thickness burns.

scholarly journals Hyaluronic acid covers in burn treatment: a systematic review

2016 ◽  
Vol 50 (3) ◽  
pp. 522-528 ◽  
Author(s):  
Michel Marcos Dalmedico ◽  
Marineli Joaquim Meier ◽  
Jorge Vinícius Cestari Felix ◽  
Franciele Soares Pott ◽  
Francislene de Fátima Cordeiro Petz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hyaluronic Acid ◽  
Randomized Controlled Trials ◽  
Complete Healing ◽  
Silver Sulfadiazine ◽  
Controlled Trials ◽  
Burn Treatment ◽  
Randomized Controlled ◽  
Partial Thickness ◽  
Partial Thickness Burns

Abstract OBJECTIVE To evaluate the effectiveness of hyaluronic acid in the healing of partial thickness burns. METHOD Systematic review of randomized controlled trials on the use of hyaluronic acid for the topical treatment of skin burns, based on recommendations of the Cochrane Handbook for Systematic Reviews of Interventions. RESULTS Two randomized controlled trials that analyzed 143 patients with partial thickness burns and/or deep partial thickness burns were selected. They compared the application of hyaluronic acid 0.2% associated to silver sulfadiazine 1% 5g/cm2 versus silver sulfadiazine 1% 5g/cm2 alone for the outcome of complete healing. CONCLUSION This review emphasizes the need for new well-designed randomized controlled trials to establish the therapeutic relevance of hyaluronic acid with respect to the healing of burns of partial thickness or deep partial thickness.

Outpatient management of partial-thickness burns: Biobrane® versus 1% silver sulfadiazine

1990 ◽  
Vol 19 (2) ◽  
pp. 121-124 ◽  
Author(s):  
Robert L Gerding ◽  
Charles L Emerman ◽  
David Effron ◽  
Thomas Lukens ◽  
Anthony L Imbembo ◽  
...  
Keyword(s):  
Silver Sulfadiazine ◽  
Outpatient Management ◽  
Partial Thickness ◽  
Partial Thickness Burns

scholarly journals Xenoderm Versus 1% Silver Sulfadiazine in Partial-thickness Burns

2009 ◽  
Vol 32 (4) ◽  
pp. 234-239 ◽  
Author(s):  
Seyed Nejat Hosseini ◽  
Anayatollah Karimian ◽  
Seyed Nouraddin Mousavinasab ◽  
Haleh Rahmanpour ◽  
Mehdi Yamini ◽  
...  
Keyword(s):  
Silver Sulfadiazine ◽  
Partial Thickness ◽  
Partial Thickness Burns

Silver Sulfadiazine Cream Treatment Results in More Wound Contraction and More Itch in a Standardized Porcine Scald Model

2021 ◽  
Author(s):  
Carlien S van den Brand ◽  
Lydia P E van der Steen ◽  
Bouke Boekema ◽  
Nanne J Paauw ◽  
Magda M W Ulrich ◽  
...  
Keyword(s):  
Healing Process ◽  
Silver Sulfadiazine ◽  
Wound Contraction ◽  
Pig Skin ◽  
Wound Model ◽  
Partial Thickness ◽  
Model Treatment ◽  
Healing Wounds ◽  
Partial Thickness Burns ◽  
Macroscopic Parameters

Abstract A variety of dressings is available for the treatment of partial-thickness wounds, but none has strong evidence supporting their beneficial effect on healing. This may be due to variation in the type and depth of wounds in clinical studies. The aim of this study was to use a standardized porcine wound model to compare three dressings commonly used in burn centers for partial-thickness burns. Partial-thickness scalds were made on the flanks of pigs. Wounds were treated with silver sulfadiazine (SSD, flammazine), a hydrofiber dressing, or glycerol-preserved allogeneic (pig) skin. The healing process was monitored for 8 weeks. Macroscopic parameters were the itching behavior, the cosmetic appearance of the scars, and contraction. Microscopic parameters were the inflammatory response, myofibroblast influx, and the numbers of nerves. All wounds were closed on day 14 and wound infection did not occur. Treatment with SSD resulted in significantly more wound contraction compared to treatment with glycerol-preserved pig skin. Animals treated with SSD suffered more from itching (scratching) during the first 2 weeks after wounding. The number of nerves in healing wounds of these animals was significantly higher compared to wounds treated with hydrofiber dressing or allogeneic skin. In our standardized porcine partial-thickness wound model, treatment with SSD resulted in less favorable wound healing. Compared to treatment with glycerol-preserved allogeneic skin, SSD resulted in more contraction.

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