THE ARTIFICIAL IRIS DIAPHRAGM FOR VITREORETINAL SILICONE OIL SURGERY

Purpose: To discuss problems associated with the implantation of two Morcher iris diaphragm models. Methods: We describe the history, intraoperative complications, and postoperative complications of 5 patients with specific Morcher iris implants. Results: We implanted Morcher 50D devices in 1 patient and Morcher 96S devices in 4 patients. Complications included postoperative rotation, device mis-sizing, difficult intraoperative rotation, zonular dehiscence, and intraoperative hemorrhage. Conclusion: Artificial iris implantation has a steep learning curve. With widespread availability on the horizon in the United States, the sharing of surgical experiences is key to achieving the best outcomes for patients.

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Artificial iris–intraocular lens implantation for traumatic aniridia and aphakia assisted by silicone oil retention sutures

Journal of Cataract & Refractive Surgery ◽

10.1016/j.jcrs.2012.08.043 ◽

2012 ◽

Vol 38 (11) ◽

pp. 2045-2048 ◽

Cited By ~ 4

Author(s):

Vittorio De Grande ◽

Ken Rosenthal ◽

Michele Reibaldi ◽

Ronald C Gentile

Keyword(s):

Intraocular Lens ◽

Silicone Oil ◽

Intraocular Lens Implantation ◽

Oil Retention ◽

Artificial Iris ◽

Lens Implantation

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Use of viscodissection and silicone oil in vitrectomy for severe diabetic retinopathy

Seminars in Ophthalmology ◽

10.1080/08820530390899150 ◽

2003 ◽

Vol 18 (3) ◽

pp. 121-126

Author(s):

Grigorian R.A. ◽

Castellarin A. ◽

Bhagat N. ◽

Del Priore ◽

Von Hagen ◽

...

Keyword(s):

Diabetic Retinopathy ◽

Silicone Oil

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Colchicine Uptake and Binding by Human Platelets

Thrombosis and Haemostasis ◽

10.1055/s-0038-1651471 ◽

1975 ◽

Vol 34 (03) ◽

pp. 780-794 ◽

Cited By ~ 4

Author(s):

Dianne M Kenney ◽

Francis C Chao ◽

James L Tullis ◽

Gail S Conneely

Keyword(s):

Time Dependence ◽

Incubation Period ◽

Binding Sites ◽

Silicone Oil ◽

Cold Treatment ◽

Human Platelets ◽

Temperature Dependent

SummaryThe uptake and binding of antimitotic alkaloid colchicine has been demonstrated in washed preparations of human platelets. A silicone oil technique was adapted so that both uptake and binding of 14C-colchicine were examined in the same platelet preparations. The time dependence and amount of colchicine taken up and bound by different platelet preparations during a 90 to 120 min incubation period were highly reproducible. Both colchicine uptake and binding by intact platelets, and colchicine binding by preparations of lysed platelets were specific and temperature dependent. Colchicine uptake was slowly reversible. Magnesium and GTP enhanced colchicine binding by lysed platelet preparations but calcium decreased binding.Exposure of platelets to either cold (4° C) or to thrombin, which disrupt platelet microtubules, produced significant increases in colchicine uptake and binding. The thrombin effect was maximal at 37° C and resulted in a greater increase in uptake and binding than that produced by either cold treatment alone or, by cold treatment followed by incubation with thrombin at 37° C. The amount of increase in uptake and binding produced by thrombin was independent of both thrombin (1–5 Units/109 platelets) and colchicine concentrations (1–50 × 10−6M).It is postulated that thrombin may initiate the formation, or make available, colchicine binding sites (microtubule subunits) within platelets.

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