scholarly journals Evaluation of Field Follow-up in a Sexually Transmitted Disease Clinic for Patients at Risk for Infection with Neisseria gonorrhoeae and Chlamydia trachomatis

1992 ◽  
Vol 19 (2) ◽  
pp. 99-104
Author(s):  
BARRY P. KATZ ◽  
VIRGINIA A. CAINE ◽  
ROBERT B. JONES
Keyword(s):  
At Risk ◽  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Sexually Transmitted Disease ◽  
Transmitted Disease ◽  
Sexually Transmitted ◽  
Disease Clinic ◽  
Sexually Transmitted Disease Clinic ◽  
Patients At Risk

Evaluation of a modified enzyme immunoassay for Neisseria gonorrhoeae in high- and low-risk females

1985 ◽  
Vol 31 (10) ◽  
pp. 893-895 ◽  
Author(s):  
Michael R. Skeels ◽  
Bessie Matsuda ◽  
Henry Horton ◽  
James Sampson ◽  
Gary A. Sawyer ◽  
...  
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Enzyme Immunoassay ◽  
Sexually Transmitted Disease ◽  
False Positive ◽  
False Negative ◽  
Transmitted Disease ◽  
Low Risk ◽  
Sexually Transmitted ◽  
Disease Clinic ◽  
Sexually Transmitted Disease Clinic

A recently modified commercial enzyme immunoassay (Gonozyme; Abbott Laboratories, North Chicago, IL) for Neisseria gonorrhoeae antigens was compared with bacteriological culture for diagnostic sensitivity, specificity, and predictive value. A total of 480 specimens were tested by both methods; 355 from females attending a sexually transmitted disease clinic ("high-risk") and 125 from female Family Planning clients ("low-risk"). Sensitivity and specificity of enzyme immunoassay for sexually transmitted disease clinic specimens were 79.7 and 97.9%, respectively (55 positive, 280 negative, 6 false positive, 14 false negative). In the low-risk population, sensitivity and specificity were 100 and 97.5%, respectively (3 positive, 119 negative, 3 false positive, 0 false negative). Despite modification, sensitivity of the method remains low for our sexually transmitted disease clinic population, but the test may have applicability for preliminary screening in low-prevalence settings.

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