Antibiotic Susceptibility Patterns and Plasmid Profiles of Penicillinase-Producing Neisseria gonorrhoeae Strains in Durban, South Africa, 1990–1993

1997 ◽  
Vol 24 (1) ◽  
pp. 18-22 ◽  
Author(s):  
HAFIZAH Y. CHENIA ◽  
BALAKRISHNA PILLAY ◽  
ANWAR A. HOOSEN ◽  
DORSAMY PILLAY
2002 ◽  
Vol 13 (2) ◽  
pp. 109-114 ◽  
Author(s):  
Torsten Berglund ◽  
Magnus Unemo ◽  
Per Olcén ◽  
Johan Giesecke ◽  
Hans Fredlund

The aim of this study was to compare epidemiological data with antibiotic susceptibility patterns, so as to characterize the risk of infection with a highly resistant Neisseria gonorrhoeae strain. N. gonorrhoeae strains isolated in Sweden from February 1998 through January 1999 were tested for antibiotic susceptibility. Epidemiological data were received from each clinician reporting a case of gonorrhoea and these data were linked to the N. gonorrhoeae strains. A total of 348 N. gonorrhoeae isolates, representing 89% of all Swedish cases diagnosed during the 12-month period, were tested for antibiotic susceptibility. Of all isolates, 24% were β-lactamase-producing, and 18% had decreased susceptibility to ciprofloxacin (MIC>0.064 mg/l). All isolates were fully susceptible to ceftriaxone and spectinomycin. More than 99% of the isolates were fully susceptible to azithromycin. The antibiotic susceptibility varied with the places where patients were exposed to infection. When exposed in Asia, 63% of the isolates showed reduced susceptibility to ciprofloxacin, compared with 0-8.5% of the isolates from patients exposed in other places (RR=8.5, P<0.001). Ciprofloxacin cannot be recommended as the first choice of treatment if the place of exposure was in Asia.


1978 ◽  
Vol 5 (4) ◽  
pp. 127-131 ◽  
Author(s):  
SUMNER E. THOMPSON ◽  
GLADYS REYNOLDS ◽  
HELEN B. SHORT ◽  
CLYDE THORNSBERRY ◽  
JAMES W. BIDDLE ◽  
...  

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