Management of Spinal Epidural Hematoma After Tissue Plasminogen Activator

Spine ◽  
1996 ◽  
Vol 21 (14) ◽  
pp. 1694-1698 ◽  
Author(s):  
E. Sander Connolly ◽  
Christopher J. Winfree ◽  
Paul C. McCormick
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Epidural Hematoma ◽  
Spinal Epidural Hematoma ◽  
Tissue Plasminogen ◽  
Spinal Epidural

scholarly journals Spinal epidural hematoma: an important stroke mimic

2013 ◽  
Vol 12 (1) ◽  
pp. 30-33
Author(s):  
James W. Schmidley ◽  
◽  
Sidney Mallenbaum ◽  
Kevin Broyles ◽  
◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Epidural Hematoma ◽  
Spinal Epidural Hematoma ◽  
Cervical Lesions ◽  
Stroke Patients ◽  
Acute Cerebral Ischemia ◽  
Tissue Plasminogen ◽  
Stroke Mimic ◽  
Acute Brain Ischemia ◽  
Spinal Epidural

Tissue plasminogen activator (tPA) is, on occasion, given to patients who do not suffer from acute cerebral ischemia. As the underlying conditions often mistaken for acute ischemic stroke tend to produce transient dysfunction, and are generally seen in individuals younger than stroke patients, the outcome of such mistaken treatment is generally benign. We will describe two elderly patients with acute hemiparesis caused by spinal epidural hematomas (SEDH), both of whom were initially considered candidates for tPA. The literature review and discussion will emphasize features allowing the distinction between these unusual hemiparetic presentations of SEDH and acute brain ischemia, and briefly review other cervical lesions that may rarely present with hemiparesis.

Spinal epidural hematoma following coronary thrombolysis with tissue plasminogen activator

1995 ◽  
Vol 83 (2) ◽  
pp. 350-353 ◽  
Author(s):  
Paul D. Sawin ◽  
Vincent C. Traynelis ◽  
Kenneth A. Follett
Keyword(s):  
Thrombolytic Therapy ◽  
Plasminogen Activator ◽  
Epidural Hematoma ◽  
Cord Compression ◽  
Neurological Dysfunction ◽  
Tissue Type ◽  
Current Status ◽  
Spinal Epidural Hematoma ◽  
Content Type ◽  
Spinal Epidural

✓ Two cases of spinal epidural hematoma following intravenous administration of recombinant tissue-type plasminogen activator are presented. Both patients received thrombolytic therapy for acute myocardial infarction; back pain and progressive neurological dysfunction ensued, secondary to spinal cord compression caused by epidural hematoma. Both individuals underwent emergency surgery for decompression and hematoma evacuation, resulting in improvement in neurological function. The current status of thrombolytic therapy is reviewed, with emphasis on complications of therapy that require neurosurgical intervention.

Worsening Cervical Epidural Hematoma After Tissue Plasminogen Activator Administration for Stroke Like Symptoms

Spine ◽  
2016 ◽  
Vol 41 (7) ◽  
pp. E437-E440 ◽  
Author(s):  
Tadatsugu Morimoto ◽  
Tomohito Yoshihara ◽  
Yusuke Yakushiji ◽  
Makoto Eriguchi ◽  
Hideo Hara ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Epidural Hematoma ◽  
Tissue Plasminogen
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