Long Term Outcomes of Allogeneic Islet Transplantation: The Collaborative Islet Transplant Registry (CITR) 1999-2010

2012 ◽  
Vol 94 (10S) ◽  
pp. 159 ◽  
Author(s):  
M. R. Rickels ◽  
T. Berney ◽  
P. Stock ◽  
P. A. Senior ◽  
R. Alejandro ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Long Term Outcomes ◽  
Islet Transplant ◽  
Transplant Registry ◽  
Islet Transplant Registry

scholarly journals Stem Cells as a Tool to Improve Outcomes of Islet Transplantation

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Emily Sims ◽  
Carmella Evans-Molina
Keyword(s):  
Stem Cells ◽  
Islet Transplantation ◽  
Insulin Independence ◽  
Islet Transplant ◽  
Edmonton Protocol ◽  
Transplant Registry ◽  
Incremental Improvement ◽  
And Function

The publication of the promising results of the Edmonton protocol in 2000 generated optimism for islet transplantation as a potential cure for Type 1 Diabetes Mellitus. Unfortunately, follow-up data revealed that less than 10% of patients achieved long-term insulin independence. More recent data from other large trials like the Collaborative Islet Transplant Registry show incremental improvement with 44% of islet transplant recipients maintaining insulin independence at three years of follow-up. Multiple underlying issues have been identified that contribute to islet graft failure, and newer research has attempted to address these problems. Stem cells have been utilized not only as a functional replacement forβcells, but also as companion or supportive cells to address a variety of different obstacles that prevent ideal graft viability and function. In this paper, we outline the manners in which stem cells have been applied to address barriers to the achievement of long-term insulin independence following islet transplantation.

217-OR: Islet Transplantation vs. Standard of Care for Type 1 Diabetes Complicated by Severe Hypoglycemia from the Collaborative Islet Transplant Registry (CITR) and T1D Exchange (T1DX) Registry

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 217-OR
Author(s):  
MICHAEL R. RICKELS ◽  
NICOLE C. FOSTER ◽  
CASSANDRA M. BALLOU ◽  
BERNHARD J. HERING ◽  
RODOLFO ALEJANDRO ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Islet Transplantation ◽  
Severe Hypoglycemia ◽  
Standard Of Care ◽  
Islet Transplant ◽  
Transplant Registry ◽  
Islet Transplant Registry

scholarly journals 2007 UPDATE ON ALLOGENEIC ISLET TRANSPLANTATION FROM THE COLLABORATIVE ISLET TRANSPLANT REGISTRY (CITR)

2008 ◽  
Vol 86 (Supplement) ◽  
pp. 84-85
Author(s):  
R Alejandro ◽  
B Hering ◽  
F Barton ◽  
M Appel ◽  
F Kandeel ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Islet Transplant ◽  
Transplant Registry ◽  
Islet Transplant Registry

Long-term Outcomes after Islet Transplantation

2014 ◽  
pp. 1314-1333
Author(s):  
A.M. James Shapiro ◽  
Camillo Ricordi
Keyword(s):  
Islet Transplantation ◽  
Long Term Outcomes

Sa1619 Long-Term Outcomes of Lung Transplantation in Patients With Hepatitis C Infection: The Data from the U.S. Transplant Registry

2016 ◽  
Vol 150 (4) ◽  
pp. S1078
Author(s):  
Aaron B. Koenig ◽  
Maria Stepanova ◽  
Sammy Saab ◽  
Aijaz Ahmed ◽  
Robert J. Wong ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Lung Transplantation ◽  
Hepatitis C Infection ◽  
Long Term Outcomes ◽  
Transplant Registry ◽  
The U.S

Results From the Inaugural Year of the Collaborative Islet Transplant Registry

2005 ◽  
Vol 37 (2) ◽  
pp. 1305-1308 ◽  
Author(s):  
N.C. Close ◽  
B.J. Hering ◽  
T.L. Eggerman
Keyword(s):  
Islet Transplant ◽  
Transplant Registry ◽  
Islet Transplant Registry
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