scholarly journals 457: EPIDEMIOLOGY AND OUTCOMES OF CHILDREN WITH DIABETIC KETOACIDOSIS AND CEREBRAL EDEMA 1997-2016

2021 ◽  
Vol 50 (1) ◽  
pp. 218-218
Author(s):  
Michael Leoncio ◽  
Paul Martinez ◽  
Prithvi Sendi ◽  
Balagangadhar Totapally
Keyword(s):  
Diabetic Ketoacidosis ◽  
Cerebral Edema

scholarly journals Cerebrovascular complications of diabetic ketoacidosis in children

2011 ◽  
Vol 55 (4) ◽  
pp. 288-290 ◽  
Author(s):  
Luis Felipe Mendonça de Siqueira
Keyword(s):  
Diabetic Ketoacidosis ◽  
Cerebral Edema ◽  
Neurological Complications ◽  
Neurological Deterioration ◽  
Cerebrovascular Complications

Neurological deterioration in children with diabetic ketoacidosis (DKA) is commonly caused by cerebral edema. However, subtle cerebral injuries including strokes should also be suspected, since children with hyperglycemia and DKA are prone to thrombosis. In this paper, a case involving a 2 month-old patient that presented cerebral edema and stroke as complications of DKA is reported. In the discussion, the literature on neurological complications of DKA in children is briefly reviewed, emphasizing the prothrombotic tendency of these patients.

Pediatric Diabetic Ketoacidosis and Hypoglycemia

2020 ◽  
Author(s):  
Rachel J Williams ◽  
Samantha L. Wood
Keyword(s):  
Emergency Department ◽  
Key Words ◽  
Diabetic Ketoacidosis ◽  
Critically Ill ◽  
Cerebral Edema ◽  
Critically Ill Patients ◽  
Pediatric Patients ◽  
Serum Glucose ◽  
Neurologic Function ◽  
Threat To Life

Abnormalities of serum glucose in pediatric patients are commonly encountered in the emergency department and represent an acute threat to life and neurologic function. Rapidly identifying and aggressively treating hyperglycemia with diabetic ketoacidosis and hypoglycemia are critical to ensure the best possible outcome. This review will guide the emergency provider in the identification, resuscitation, workup, and disposition of these critically ill patients. This review contains 6 figures, 13 tables, and 50 reviews. Key Words: Cerebral edema, diabetic ketoacidosis, hyperglycemia, hypoglycemia

A RARE CASE MORTALITY OF DIABETIC KETOACIDOSIS- CEREBRAL EDEMA WITH TONSILLAR HERNIATION- A CONTRADICTORY OPINION.IS SODIUM BICARBONATE A REAL CULPRIT?

2021 ◽  
pp. 8-10
Author(s):  
Sruthi P ◽  
Manzoor Sharieff M ◽  
Prasanth Kumar P ◽  
Vishnu priya V ◽  
Nagarajan N ◽  
...  
Keyword(s):  
Diabetic Ketoacidosis ◽  
Cerebral Edema ◽  
Hydrogen Exchange ◽  
Ketone Bodies ◽  
Acetoacetic Acid ◽  
Tonsillar Herniation ◽  
Sodium Hydrogen ◽  
Uncontrolled Diabetes ◽  
Case Mortality

Diabetic ketoacidosis (DKA) is the most common complication seen in uncontrolled diabetes mellitus. DKA is most commonly seen with patients of type 1 diabetes. Depletion of Insulin leads to high blood sugars which in turn leads osmotic diuresis, production of ketone bodies i.e, βhydroxybutyric acid and acetoacetic acid, dysregulation of sodium hydrogen exchange mechanism[2]. As a consequence to the above stated mechanisms, cerebral edema has been documented as a fatal complication in DKA. Mortality documented due to cerebral edema is 21-25%[4].

scholarly journals Diabetic Ketoacidosis-Associated Stroke in Children and Youth

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Jennifer Ruth Foster ◽  
Gavin Morrison ◽  
Douglas D. Fraser
Keyword(s):  
Diabetic Ketoacidosis ◽  
Cerebral Edema ◽  
Vascular Reactivity ◽  
Brain Infarction ◽  
Coagulation Factors ◽  
Children And Youth ◽  
Vascular Endothelial ◽  
Thrombotic Risk ◽  
Hemorrhagic Risk ◽  
Ischemic Brain Infarction

Diabetic ketoacidosis (DKA) is a state of severe insulin deficiency, either absolute or relative, resulting in hyperglycemia and ketonemia. Although possibly underappreciated, up to 10% of cases of intracerebral complications associated with an episode of DKA, and/or its treatment, in children and youth are due to hemorrhage or ischemic brain infarction. Systemic inflammation is present in DKA, with resultant vascular endothelial perturbation that may result in coagulopathy and increased hemorrhagic risk. Thrombotic risk during DKA is elevated by abnormalities in coagulation factors, platelet activation, blood volume and flow, and vascular reactivity. DKA-associated cerebral edema may also predispose to ischemic injury and hemorrhage, though cases of stroke without concomitant cerebral edema have been identified. We review the current literature regarding the pathogenesis of stroke during an episode of DKA in children and youth.

Diabetic Ketoacidosis with Cerebral Edema

2015 ◽  
pp. 79-79
Author(s):  
Eesh Bhatia ◽  
Vijayalakshmi Bhatia ◽  
Siddhnath Sudhanshu
Keyword(s):  
Diabetic Ketoacidosis ◽  
Cerebral Edema
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