In premenopausal women with low sexual desire, is flibanserin (Addyi®) an effective and safe treatment?

2018 ◽  
Vol 21 (4) ◽  
pp. E12
Author(s):  
Molly Benedum
Keyword(s):  
Sexual Desire ◽  
Premenopausal Women ◽  
Safe Treatment ◽  
Low Sexual Desire

The Bio-Psycho-Social Dimension in Women’s Sexual Desire: ‘Argumentum ad novitatem’

2018 ◽  
Vol 20 (2) ◽  
pp. 146-157 ◽  
Author(s):  
Nur Syazwani Roslan ◽  
Nik Ruzyanei Nik Jaafar ◽  
Hatta Sidi ◽  
Najwa Baharudin ◽  
Jaya Kumar ◽  
...  
Keyword(s):  
Sexual Desire ◽  
Drug Targets ◽  
Partial Agonist ◽  
Premenopausal Women ◽  
Hormonal Treatment ◽  
Neural Mechanism ◽  
Social Dimension ◽  
Core Knowledge ◽  
Low Sexual Desire

Sexual desire includes complex motivation and drive. In the context of biological and cognitive- emotive state art of science, it is often a neglected field in medicine. In regard to the treatment, study on women’s sexual function received less attention compared to the men’s sexuality. In the past, this endeavor was relatively not well disseminated in the scientific community. Recently, there was a revolutionized surge of drug targets available to treat women with low sexual desire. It is timely to review the relevant biological approach, especially in the context of pharmacotherapy to understand this interesting clinical entity which was modulated by numerous interactive psychosocial inter-play and factors. The complex inter-play between numerous dimensional factors lends insights to understand the neural mechanism, i.e. the rewards centre pathway and its interaction with external psychosocialstimulus, e.g. relationship or other meaningful life events. The function of hormones, e.g. oxytocin or testosterone regulation was described. The role of neurotransmitters as reflected by the introduction of a molecule of flibenserin, a full agonist of the 5-HT1A and partial agonist of the D4 to treat premenopausal women with low sexual desire was deliberated. Based on this fundamental scientific core knowledge, we suggest an outline on know-how of introduction for sex therapy (i.e. “inner-self” and “outer-self”) where the role of partner is narrated. Then, we also highlighted on the use of pharmacological agent as an adjunct scope of therapy, i.e. phosphodiasterase-5 (PDE-5) inhibitors and hormonal treatment in helping the patient with low sexual desire.

Efficacy and safety of testosterone patches for the treatment of low sexual desire in surgically menopausal women

2003 ◽  
Vol 80 ◽  
pp. 76 ◽  
Author(s):  
S. Davis ◽  
M. Rees ◽  
C. Ribot ◽  
A. Moufarege ◽  
C. Rodenberg ◽  
...  
Keyword(s):  
Sexual Desire ◽  
Efficacy And Safety ◽  
Low Sexual Desire ◽  
Menopausal Women

Low sexual desire: The role of anxiety, depression and marital adjustment

1997 ◽  
Vol 12 (1) ◽  
pp. 95-99 ◽  
Author(s):  
Gilles Trudel ◽  
Lyne Landry ◽  
Yvette Larose
Keyword(s):  
Sexual Desire ◽  
Marital Adjustment ◽  
Low Sexual Desire ◽  
Anxiety Depression

scholarly journals Free Serum Testosterone Versus Total Testosterone/Estradiol Ratio in Low Sexual Desire in Old Men

2021 ◽  
Vol 83 (1) ◽  
pp. 1062-1067
Author(s):  
Ahmed SA Abouroab ◽  
Sherif Refaat Ismail ◽  
Hamdy Foad Aly Marzok
Keyword(s):  
Sexual Desire ◽  
Serum Testosterone ◽  
Total Testosterone ◽  
Low Sexual Desire ◽  
Old Men ◽  
Free Serum

Low sexual desire in women: The role of reproductive hormones

1989 ◽  
Vol 23 (2) ◽  
pp. 221-234 ◽  
Author(s):  
Patricia Schreiner-Engel ◽  
Raul C. Schiavi ◽  
Daniel White ◽  
Anna Ghizzani
Keyword(s):  
Sexual Desire ◽  
Reproductive Hormones ◽  
Low Sexual Desire

Treatment of Hypoactive Sexual Desire Disorder in Premenopausal Women: Efficacy of Flibanserin in the VIOLET Study

2012 ◽  
Vol 9 (4) ◽  
pp. 1074-1085 ◽  
Author(s):  
Leonard R. DeRogatis ◽  
Lawrence Komer ◽  
Molly Katz ◽  
Michèle Moreau ◽  
Toshio Kimura ◽  
...  
Keyword(s):  
Sexual Desire ◽  
Premenopausal Women ◽  
Hypoactive Sexual Desire Disorder ◽  
Desire Disorder

A Review of Recent Innovations in the Treatment of Low Sexual Desire

2018 ◽  
Vol 10 (4) ◽  
pp. 281-286 ◽  
Author(s):  
Maxime Charest ◽  
Peggy J. Kleinplatz
Keyword(s):  
Sexual Desire ◽  
Low Sexual Desire
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