EARLY TARGET ORGAN DAMAGE IN PATIENTS WITH PHEOCHROMOCYTOMA, OBSTRUCTIVE SLEEP APNEA AND ESSENTIAL HYPERTENSION: PP.18.196

2010 ◽  
Vol 28 ◽  
pp. e307-e308 ◽  
Author(s):  
P Zielen ◽  
M Peczkowska ◽  
A Prejbisz ◽  
K Michel-Rowicka ◽  
T Zielinski ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Essential Hypertension ◽  
Sleep Apnea ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Obstructive Sleep

Nocturnal Hypertension, Nondipping Phenomenon and Target Organ Damage in Obstructive Sleep Apnea Patients - The Bad and the Worse

2015 ◽  
Vol 10 (3) ◽  
pp. 182-188 ◽  
Author(s):  
Radostina Vlaeva Cherneva ◽  
Ognian Borisov Georgiev ◽  
Daniela Stoichkova Petrova ◽  
Emil Ivanov Manov ◽  
Dinko Georgiev Valev ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Nocturnal Hypertension ◽  
Obstructive Sleep

scholarly journals Possible mechanisms of drug-resistance in hypertensive patients with obstructive sleep apnea

2012 ◽  
Vol 18 (3) ◽  
pp. 184-190 ◽  
Author(s):  
N. E. Zvartau ◽  
YU. V. Sviryaev ◽  
L. S. Korostovtseva ◽  
A. O. Konradi
Keyword(s):  
Drug Resistance ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Negative Impact ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Hypertensive Patients ◽  
Obstructive Sleep ◽  
Stimulation Of

The article reviews possible mechanisms responsible for drug resistance in hypertensive patients with obstructive sleep apnea. Data about more profound target organ damage, partly explained by activation of inflammation, endothelial dysfunction due to recurrent hypoxia episodes and by blood pressure pattern in apnea patients are presented. Stimulation of renin-angiotensin-aldosterone system has a negative impact on cardiovascular system and deteriorates sleep apnea severity.

scholarly journals Resistant Hypertension and Obstructive Sleep Apnea: The Sparring Partners

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Costas Thomopoulos ◽  
Helena Michalopoulou ◽  
Alexandros Kasiakogias ◽  
Anna Kefala ◽  
Thomas Makris
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Resistant Hypertension ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Pharmacological Therapy ◽  
Upper Body ◽  
Favorable Effect ◽  
Obstructive Sleep ◽  
Mineralocorticoid Antagonists

Enhanced target organ damage and cardiovascular morbidity represent common issues observed in both resistant hypertension and obstructive sleep apnea. Common pathophysiological features and risk factors justify their coexistence, especially in individuals with increased upper-body adiposity. Impaired sodium handling, sympathetic activation, accelerated arterial stiffening, and impaired cardiorenal hemodynamics contribute to drug-resistant hypertension development in obstructive sleep apnea. Effective CPAP therapy qualifies as an effective “add-on” to the underlying antihypertensive pharmacological therapy, and emerging evidence underlines the favorable effect of mineralocorticoid antagonists on both resistant hypertension and obstructive sleep apnea treatment.

scholarly journals The controversial role of serum uric acid in essential hypertension: relationships with indices of target organ damage

2005 ◽  
Vol 19 (3) ◽  
pp. 211-217 ◽  
Author(s):  
C Tsioufis ◽  
D Chatzis ◽  
E Vezali ◽  
K Dimitriadis ◽  
D Antoniadis ◽  
...  
Keyword(s):  
Uric Acid ◽  
Essential Hypertension ◽  
Serum Uric Acid ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ

Relationships between 24 h blood pressure load and target organ damage in patients with mild-to-moderate essential hypertension

2001 ◽  
Vol 6 (3) ◽  
pp. 115-123 ◽  
Author(s):  
Giuseppe Mulè ◽  
Emilio Nardi ◽  
Giuseppe Andronico ◽  
Santina Cottone ◽  
Francesco Raspanti ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Moderate Essential Hypertension ◽  
Target Organ ◽  
Pressure Load ◽  
Blood Pressure Load

Essential hypertension: Diagnosis, assessment, and treatment

2020 ◽  
pp. 3753-3778
Author(s):  
Bryan Williams ◽  
John D. Firth
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Severe Hypertension ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Elevated Blood ◽  
Hypertensive Patients ◽  
Assessment And Treatment ◽  
Hypertension Diagnosis

Essential hypertension is invariably symptomless and usually detected by routine screening or opportunistic measurement of blood pressure. However, once a patient has been labelled as ‘hypertensive’ it is not uncommon for them to associate preceding symptoms to their elevated blood pressure. Some patients will claim that they can recognize when their blood pressure is elevated, usually on the basis of symptoms such as plethoric features, palpitations, dizziness, or a feeling of tension. Screening surveys have demonstrated that these symptoms occur no more commonly in untreated hypertensive patients than they do in the normotensive population. However, there are two important caveats to the symptomless nature of essential hypertension: (1) symptoms may develop as a consequence of target organ damage, (2) headache may be a feature of severe hypertension.

Correlation between blood pressure variability and subclinical target organ damage in patients with essential hypertension

2019 ◽  
Vol 34 (9) ◽  
pp. 641-647 ◽  
Author(s):  
Mostafa El Mokadem ◽  
Hesham Boshra ◽  
Yasser Abd el Hady ◽  
Amany Kasla ◽  
Ahmed Gouda
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Blood Pressure Variability ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ

scholarly journals The cumulative blood pressure load and target organ damage in patients with essential hypertension

2020 ◽  
Vol 22 (6) ◽  
pp. 981-990
Author(s):  
Bingqing Zhou ◽  
Chuanwei Li ◽  
Jialing Shou ◽  
Yu Zhang ◽  
Chunlan Wen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Pressure Load ◽  
Blood Pressure Load
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